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The mammalian brain could contain dense and sparse network connectivity structures, including both excitatory and inhibitory neurons, but is without any clearly defined output layer. The neurons have time constants, which mean that the…

Neurons and Cognition · Quantitative Biology 2021-06-04 Udaya B. Rongala , Henrik Jörntell

In this paper we present a language for finite state continuous time Bayesian networks (CTBNs), which describe structured stochastic processes that evolve over continuous time. The state of the system is decomposed into a set of local…

Artificial Intelligence · Computer Science 2013-01-07 Uri Nodelman , Christian R. Shelton , Daphne Koller

Recording simultaneous activity of hundreds of neurons is now possible. Existing methods can model such population activity, but do not directly reveal the computations used by the brain. We present a fully unsupervised method that models…

Neurons and Cognition · Quantitative Biology 2020-03-24 Connor Brennan , Alex Proekt

The effects of the finite size of the network on the evolutionary dynamics of a Boolean network are analyzed. In the model considered, Boolean networks evolve via a competition between nodes that punishes those in the majority. It is found…

Statistical Mechanics · Physics 2016-09-08 Min Liu , Kevin E. Bassler

Canalizing functions have important applications in physics and biology. For example, they represent a mechanism capable of stabilizing chaotic behavior in Boolean network models of discrete dynamical systems. When comparing the class of…

Mathematical Physics · Physics 2009-11-10 Winfried Just , Ilya Shmulevich , John Konvalina

In a balancing network each processor has an initial collection of unit-size jobs (tokens) and in each round, pairs of processors connected by balancers split their load as evenly as possible. An excess token (if any) is placed according to…

Data Structures and Algorithms · Computer Science 2010-06-09 Tobias Friedrich , Thomas Sauerwald , Dan Vilenchik

We consider a basic model of a dynamical distribution network, modeled as a directed graph with storage variables corresponding to every vertex and flow inputs corresponding to every edge, subject to unknown but constant inflows and…

Optimization and Control · Mathematics 2014-03-21 Jieqiang Wei , Arjan J. van der Schaft

Canalization of genetic regulatory networks has been argued to be favored by evolutionary processes due to the stability that it can confer to phenotype expression. We explore whether a significant amount of canalization and partial…

Quantitative Methods · Quantitative Biology 2009-11-13 C. J. Olson Reichhardt , Kevin E. Bassler

Threshold-linear networks consist of simple units interacting in the presence of a threshold nonlinearity. Competitive threshold-linear networks have long been known to exhibit multistability, where the activity of the network settles into…

Neurons and Cognition · Quantitative Biology 2023-10-17 Katherine Morrison , Anda Degeratu , Vladimir Itskov , Carina Curto

A communication network is said to be "anonymous" if its agents are indistinguishable from each other; it is "dynamic" if its communication links may appear or disappear unpredictably over time. Assuming that each of the $n$ agents of an…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-08-26 Giuseppe A. Di Luna , Giovanni Viglietta

Boolean networks have been the object of much attention, especially since S. Kauffman proposed them in the 1960's as models for gene regulatory networks. These systems are characterized by being defined on a Boolean state space and by…

Molecular Networks · Quantitative Biology 2007-11-21 German A. Enciso , Winfried Just

We present the notion of stateful priorities for imposing precise restrictions on system actions, in order to meet safety constraints. By using stateful priorities we are able to exclusively restrict erroneous system behavior as specified…

Logic in Computer Science · Computer Science 2020-02-21 Christian Herrera

Motivated by questions in biology and distributed computing, we investigate the behaviour of particular cellular automata, modelled as one-dimensional arrays of identical finite automata. We investigate what sort of self-stabilising…

Formal Languages and Automata Theory · Computer Science 2009-11-14 Alan Gibbons , Martyn Amos

The concept of a nested canalizing Boolean function has been studied over the course of the last decade in the context of understanding the regulatory logic of molecular interaction networks, such as gene regulatory networks. Such functions…

Dynamical Systems · Mathematics 2013-04-15 J. O. Adeyeye , C. Kadelka , R. Laubenbacher , Y. Li

Despite their topological complexity almost all functional properties of metabolic networks can be derived from steady-state dynamics. Indeed, many theoretical investigations (like flux-balance analysis) rely on extracting function from…

Molecular Networks · Quantitative Biology 2009-11-13 Carsten Marr , Mark Mueller-Linow , Marc-Thorsten Huett

Neural network modules conditioned by known priors can be effectively trained and combined to represent systems with nonlinear dynamics. This work explores a novel formulation for data-efficient learning of deep control-oriented nonlinear…

Dynamical Systems · Mathematics 2021-01-07 Elliott Skomski , Soumya Vasisht , Colby Wight , Aaron Tuor , Jan Drgona , Draguna Vrabie

Boolean networks are used to model biological networks such as gene regulatory networks. Often Boolean networks show very chaotic behavior which is sensitive to any small perturbations.In order to reduce the chaotic behavior and to attain…

Systems and Control · Computer Science 2014-09-16 Camellia Ray , Jayanta Kumar Das , Pabitra Pal Choudhury

We study a simple deterministic map that leads a fully connected network to Heider balance. The map is realized by an algorithm that updates all links synchronously in a way depending on the state of the entire network. We observe that the…

Cellular Automata and Lattice Gases · Physics 2021-08-18 Malgorzata J. Krawczyk , Krzysztof Kulakowski , Zdzislaw Burda

In this paper, we propose a general mathematical framework to represent many multi-agent signalling systems in recent works. Our goal is to apply previous results in monotonicity to this class of systems and study their asymptotic behavior.…

Dynamical Systems · Mathematics 2013-07-19 Chjan C. Lim , Weituo Zhang

Deterministic and stochastic Boolean network models are build for the dynamics of negative feedback loops of the p53 pathways. It is shown that the main function of the negative feedback in the p53 pathways is to keep p53 at a low steady…

Molecular Networks · Quantitative Biology 2009-04-16 Hao Ge , Min Qian