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mlpack is an open-source C++ machine learning library with an emphasis on speed and flexibility. Since its original inception in 2007, it has grown to be a large project implementing a wide variety of machine learning algorithms, from…

Mathematical Software · Computer Science 2017-08-31 Ryan R. Curtin , Marcus Edel

In drug discovery, molecular dynamics (MD) simulation for protein-ligand binding provides a powerful tool for predicting binding affinities, estimating transport properties, and exploring pocket sites. There has been a long history of…

We present our latest advancements of machine-learned potentials (MLPs) based on the neuroevolution potential (NEP) framework introduced in [Fan et al., Phys. Rev. B 104, 104309 (2021)] and their implementation in the open-source package…

The RMPCDMD software package performs hybrid Molecular Dynamics simulations, coupling Multiparticle Collision Dynamics to model the solvent and Molecular Dynamics to model suspended colloids, including hydrodynamics, thermal fluctuations,…

Computational Physics · Physics 2017-01-13 Pierre de Buyl , Mu-Jie Huang , Laurens Deprez

The emergence of Multimodal Large Language Models ((M)LLMs) has ushered in new avenues in artificial intelligence, particularly for autonomous driving by offering enhanced understanding and reasoning capabilities. This paper introduces…

Robotics · Computer Science 2024-04-15 Daocheng Fu , Wenjie Lei , Licheng Wen , Pinlong Cai , Song Mao , Min Dou , Botian Shi , Yu Qiao

Simulations of colloidal suspensions consisting of mesoscopic particles and smaller species such as ions or depletants are computationally challenging as different length and time scales are involved. Here, we introduce a machine learning…

Soft Condensed Matter · Physics 2021-12-01 Gerardo Campos-Villalobos , Emanuele Boattini , Laura Filion , Marjolein Dijkstra

Cognitive Diagnosis (CD) has become a critical task in AI-empowered education, supporting personalized learning by accurately assessing students' cognitive states. However, traditional CD models often struggle in cold-start scenarios due to…

Computation and Language · Computer Science 2025-05-28 Yu He , Zihan Yao , Chentao Song , Tianyu Qi , Jun Liu , Ming Li , Qing Huang

Meshfree simulation methods are emerging as compelling alternatives to conventional mesh-based approaches, particularly in the fields of Computational Fluid Dynamics (CFD) and continuum mechanics. In this publication, we provide a…

Machine Learning · Computer Science 2024-03-21 Paulami Banerjee , Mohan Padmanabha , Chaitanya Sanghavi , Isabel Michel , Simone Gramsch

Molecular dynamics simulations have emerged as a fundamental instrument for studying biomolecules. At the same time, it is desirable to perform simulations of a collection of particles under various conditions in which the molecules can…

Machine Learning · Computer Science 2023-10-11 Jingbang Chen , Yian Wang , Xingwei Qu , Shuangjia Zheng , Yaodong Yang , Hao Dong , Jie Fu

We provide an introduction to molecular dynamics simulations in the context of the Kob-Andersen model of a glass. We introduce a complete set of tools for doing and analyzing the results of simulations at fixed NVE and NVT. The modular…

Computational Physics · Physics 2020-05-25 K. Vollmayr-Lee

There are many ways to represent a molecule as input to a machine learning model and each is associated with loss and retention of certain kinds of information. In the interest of preserving three-dimensional spatial information, including…

Machine Learning · Computer Science 2019-12-11 Jocelyn Sunseri , David Ryan Koes

Learning-based control methods are an attractive approach for addressing performance and efficiency challenges in robotics and automation systems. One such technique that has found application in these domains is learning-based model…

Optimization and Control · Mathematics 2014-04-11 Anil Aswani , Patrick Bouffard , Xiaojing Zhang , Claire Tomlin

Molecular dynamics simulations are an important tool for describing the evolution of a chemical system with time. However, these simulations are inherently held back either by the prohibitive cost of accurate electronic structure theory…

Chemical Physics · Physics 2018-12-20 Michael Gastegger , Philipp Marquetand

Liquid metals are central to energy-storage and nuclear technologies, yet quantitative knowledge of their thermophysical properties remains limited. While atomistic simulations offer a route to computing liquid properties directly from…

Materials Science · Physics 2026-01-09 Alex Tai , Jason Ogbebor , Rodrigo Freitas

Machine learning interatomic potentials (MLIPs) enable atomistic simulations with near ab initio accuracy at significantly reduced computational cost, but their broader adoption is often limited by fragmented tooling, limited scalability,…

The recent advancements introduced by Large Language Models (LLMs) have transformed how Artificial Intelligence (AI) can support complex, real world tasks, pushing research outside the text boundaries towards multi modal contexts and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Federico Toschi , Nicolò Brunello , Andrea Sassella , Vincenzo Scotti , Mark James Carman

We introduce sbml4md, a newly developed algorithm implemented as a software package to extract parameters of multimode anharmonic Brownian (MAB) models from molecular dynamics (MD) trajectories for simulating nonlinear vibrational spectra…

Chemical Physics · Physics 2026-03-20 Kwanghee Park , Seiji Ueno , Yoshitaka Tanimura

Symbolic Machine Learning Prover (SMLP) is a tool and a library for system exploration based on data samples obtained by simulating or executing the system on a number of input vectors. SMLP aims at exploring the system based on this data…

Machine Learning · Computer Science 2024-02-05 Franz Brauße , Zurab Khasidashvili , Konstantin Korovin

The study by Jung et al. (Jung H, Covino R, Arjun A, et al., Nat Comput Sci. 3:334-345 (2023)) introduced Artificial Intelligence for Molecular Mechanism Discovery (AIMMD), a novel sampling algorithm that integrates machine learning to…

Computational Physics · Physics 2026-02-06 Porhouy Minh , Sapna Sarupria

We report a novel hybrid method of simultaneous atomistic simulation of solids in critical regions (contacts surfaces, cracks areas, etc.), along with continuum modeling of other parts. The continuum is treated in terms of quasi-atoms of…

Materials Science · Physics 2026-02-17 Artem Chuprov , Egor E. Nuzhin , Alexey A. Tsukanov , Nikolay V. Brilliantov