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Machine learning force fields have emerged as promising tools for molecular dynamics (MD) simulations, potentially offering quantum-mechanical accuracy with the efficiency of classical MD. Inspired by foundational large language models,…

Computational Physics · Physics 2025-11-14 Denan Li , Jiyuan Yang , Xiangkai Chen , Lintao Yu , Shi Liu

The two-field vibroacoustic finite-element (FE) model requires a relatively large number of degrees of freedom compared to the monophysics model, and the conventional force identification method for structural vibration can be adjusted for…

Computational Engineering, Finance, and Science · Computer Science 2022-11-23 Seungin Oh , Chang-uk Ahn , Kwanghyun Ahn , Jin-Gyun Kim

Antibodies, crucial for immune defense, primarily rely on complementarity-determining regions (CDRs) to bind and neutralize antigens, such as viruses. The design of these CDRs determines the antibody's affinity and specificity towards its…

Quantitative Methods · Quantitative Biology 2024-09-10 Paulina Kulytė , Francisco Vargas , Simon Valentin Mathis , Yu Guang Wang , José Miguel Hernández-Lobato , Pietro Liò

A multiphysics phase field model is used for the computational study of memristive thin film morphology and current-voltage hysteresis. In contrast to previous computational methods, no requirements are made on conducting filament geometry.…

Materials Science · Physics 2025-06-24 John F. Sevic , Ambroise Juston , Nobuhiko P. Kobayashi

Reactive chemistry of molecular hydrogen at surfaces, notably dissociative sticking and hydrogen evolution, plays a crucial role in energy storage and fuel cells. Theoretical studies can help to decipher underlying mechanisms and reaction…

Interface cracking is one of the most prominent failure modes in fibre reinforced polymer (FRP) composites. Recent trends in high-tech applications of FRP composites exploit the limits of the load bearing capacity, generally encompassing…

Materials Science · Physics 2020-05-28 L. García-Guzmán , J. Reinoso , A. Valverde , E. Martínez-Pañeda , L. Távara

Fluid-Structure Interaction (FSI) can be investigated by means of non-linear Finite Element Models (FEM), suitable to capture large deflections of structural parts interacting with fluids, and Computational Fluid Dynamics (CFD). High…

Accounting for nuclear quantum effects (NQEs) can significantly alter material properties at finite temperatures. Atomic modeling using the path-integral molecular dynamics (PIMD) method can fully account for such effects, but requires…

Materials Science · Physics 2025-05-21 A. A. Solovykh , N. E. Rybin , I. S. Novikov , A. V. Shapeev

The local structure of a protein strongly impacts its function and interactions with other molecules. Therefore, a concise, informative representation of a local protein environment is essential for modeling and designing proteins and…

We propose a method to efficiently determine the optimal coarse-grained force field in mesoscopic stochastic simulations of Newtonian fluid and polymer melt systems modeled by dissipative particle dynamics (DPD) and energy conserving…

Computational Physics · Physics 2017-01-04 Huan Lei , Xiu Yang , Zhen Li , George Karniadakis

High-accuracy, high-efficiency physics-based fluid-solid interaction is essential for reality modeling and computer animation in online games or real-time Virtual Reality (VR) systems. However, the large-scale simulation of incompressible…

Graphics · Computer Science 2023-05-08 Jin Li , Yang Gao , Ju Dai , Shuai Li , Aimin Hao , Hong Qin

Classical molecular dynamics (MD) simulations enable modeling of materials and examination of microscopic details that are not accessible experimentally. The predictive capability of MD relies on the force field (FF) used to describe…

Molecular Dynamics (MD) simulations are a powerful tool for studying matter at the atomic scale. However, to simulate solids, an initial atomic structure is crucial for the successful execution of MD simulations, but can be difficult to…

Computational Physics · Physics 2024-11-27 Lars Dammann , Richard Kohns , Patrick Huber , Robert H. Meißner

Covalent Organic Frameworks (COFs) are versatile two-dimensional (2D) materials for flexible electronics, catalysis, and sensing, owing to their tunable architectures and large surface areas. However, like most materials, COFs inevitably…

Active nematics, formed from a liquid crystalline suspension of active force dipoles, are a paradigmatic active matter system whose study provides insights into how chemical driving produces the cellular mechanical forces essential for…

Soft Condensed Matter · Physics 2024-11-15 Carlos Floyd , Aaron R. Dinner , Suriyanarayanan Vaikuntanathan

Modern machine learning force fields (ML-FF) are able to yield energy and force predictions at the accuracy of high-level $ab~initio$ methods, but at a much lower computational cost. On the other hand, classical molecular mechanics force…

This work presents new tools for studying reachability and set invariance for continuous-time mixed-monotone dynamical systems subject to a disturbance input. The vector field of a mixed-monotone system is decomposable via a decomposition…

Systems and Control · Electrical Eng. & Systems 2020-08-25 Matthew Abate , Samuel Coogan

Nonlinear manifold learning (ML) based reduced-order models (ROMs) can substantially improve the quality of nonlinear flow-field modeling. However, noise and the lack of physical information often distort the dimensionality-reduction…

Fluid Dynamics · Physics 2026-01-21 Weiji Wang , Chunlin Gong , Xuyi Jia , Chunna Li

Robotic fabric manipulation is challenging due to the infinite dimensional configuration space, self-occlusion, and complex dynamics of fabrics. There has been significant prior work on learning policies for specific deformable manipulation…

Harnessing the rich nonlinear dynamics of highly-deformable materials has the potential to unlock the next generation of functional smart materials and devices. However, unlocking such potential requires effective strategies to spatially…

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