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Bayesian methods have received increasing attention in medical research, where sensitivity analysis of prior distributions is essential. Such analyses typically require the evaluation of the posterior distribution of a parameter under…

Methodology · Statistics 2025-10-14 Tomohiro Ohigashi , Shonosuke Sugasawa

Approximate Bayesian computation (ABC) is an approach for sampling from an approximate posterior distribution in the presence of a computationally intractable likelihood function. A common implementation is based on simulating model,…

Methodology · Statistics 2013-01-16 D. Prangle , M. G. B. Blum , G. Popovic , S. A. Sisson

Bayesian interpretations of neural processing require that biological mechanisms represent and operate upon probability distributions in accordance with Bayes' theorem. Many have speculated that synaptic failure constitutes a mechanism of…

Neurons and Cognition · Quantitative Biology 2022-10-05 Kevin McKee , Ian Crandell , Rishidev Chaudhuri , Randall O'Reilly

In this paper, a Bayesian inference technique based on Taylor series approximation of the logarithm of the likelihood function is presented. The proposed approximation is devised for the case, where the prior distribution belongs to the…

Machine Learning · Computer Science 2015-10-06 Tohid Ardeshiri , Umut Orguner , Fredrik Gustafsson

In Bayesian optimization, accounting for the importance of the output relative to the input is a crucial yet challenging exercise, as it can considerably improve the final result but often involves inaccurate and cumbersome entropy…

Machine Learning · Computer Science 2020-12-30 Antoine Blanchard , Themistoklis Sapsis

A Bayes factor is proposed for testing whether the effect of a key predictor variable on the dependent variable is linear or nonlinear, possibly while controlling for certain covariates. The test can be used (i) when one is interested in…

Methodology · Statistics 2021-09-16 Joris Mulder

Accurate simulation of complex physical systems enables the development, testing, and certification of control strategies before they are deployed into the real systems. As simulators become more advanced, the analytical tractability of the…

Robotics · Computer Science 2020-05-27 Lucas Barcelos , Rafael Oliveira , Rafael Possas , Lionel Ott , Fabio Ramos

In recent years, Bayesian inference in large-scale inverse problems found in science, engineering and machine learning has gained significant attention. This paper examines the robustness of the Bayesian approach by analyzing the stability…

Machine Learning · Statistics 2023-03-06 Alfredo Garbuno-Inigo , Tapio Helin , Franca Hoffmann , Bamdad Hosseini

The interpretation of data in terms of multi-parameter models of new physics, using the Bayesian approach, requires the construction of multi-parameter priors. We propose a construction that uses elements of Bayesian reference analysis. Our…

Data Analysis, Statistics and Probability · Physics 2011-08-03 Maurizio Pierini , Harrison B. Prosper , Sezen Sekmen , Maria Spiropulu

Gaussian process regression is a frequently used statistical method for flexible yet fully probabilistic non-linear regression modeling. A common obstacle is its computational complexity which scales poorly with the number of observations.…

Methodology · Statistics 2026-03-10 Adam Gorm Hoffmann , Claus Thorn Ekstrøm , Andreas Kryger Jensen

We derive a family of loss functions to train models in the presence of sampling bias. Examples are when the prevalence of a pathology differs from its sampling rate in the training dataset, or when a machine learning practioner rebalances…

Use of historical control data to augment a small internal control arm in a randomized control trial (RCT) can lead to significant improvement of the efficiency of the trial. It introduces the risk of potential bias, since the historical…

Methodology · Statistics 2022-10-05 Jixian Wang , Hongtao Zhang , Ram Tiwari

Bayesian statistics is concerned with conducting posterior inference for the unknown quantities in a given statistical model. Conventional Bayesian inference requires the specification of a probabilistic model for the observed data, and the…

Methodology · Statistics 2023-05-11 David T. Frazier , Christopher Drovandi , David J. Nott

Bayesian model comparison implements Occam's razor through its sensitivity to the prior. However, prior-dependence makes it important to assess the influence of plausible alternative priors. Such prior sensitivity analyses for the Bayesian…

Methodology · Statistics 2026-01-22 Zixiao Hu , Jason D. McEwen

Datasets are rarely a realistic approximation of the target population. Say, prevalence is misrepresented, image quality is above clinical standards, etc. This mismatch is known as sampling bias. Sampling biases are a major hindrance for…

Bayesian data analysis is about more than just computing a posterior distribution, and Bayesian visualization is about more than trace plots of Markov chains. Practical Bayesian data analysis, like all data analysis, is an iterative process…

Methodology · Statistics 2019-01-31 Jonah Gabry , Daniel Simpson , Aki Vehtari , Michael Betancourt , Andrew Gelman

In recent years, the transformer has established itself as a workhorse in many applications ranging from natural language processing to reinforcement learning. Similarly, Bayesian deep learning has become the gold-standard for uncertainty…

Machine Learning · Computer Science 2021-10-18 Tristan Cinquin , Alexander Immer , Max Horn , Vincent Fortuin

Using instruments comprising ordered responses to items are ubiquitous for studying many constructs of interest. However, using such an item response format may lead to items with response categories infrequently endorsed or unendorsed…

Methodology · Statistics 2024-05-02 R. Noah Padgett , Grant B. Morgan , Tim Lomas

Advancements in computational power and methodologies have enabled research on massive datasets. However, tools for analyzing data with directional or periodic characteristics, such as wind directions and customers' arrival time in 24-hour…

Methodology · Statistics 2026-04-07 Xiang Ye , Janet Van Niekerk , Håvard Rue

We report the application of implicit likelihood inference to the prediction of the macro-parameters of strong lensing systems with neural networks. This allows us to perform deep learning analysis of lensing systems within a well-defined…

Instrumentation and Methods for Astrophysics · Physics 2023-01-25 Ronan Legin , Yashar Hezaveh , Laurence Perreault-Levasseur , Benjamin Wandelt