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Large biological datasets are being produced at a rapid pace and create substantial storage challenges, particularly in the domain of high-throughput sequencing (HTS). Most approaches currently used to store HTS data are either unable to…

Quantitative Methods · Quantitative Biology 2014-03-05 Fabien Campagne , Kevin C. Dorff , Nyasha Chambwe , James T. Robinson , Jill P. Mesirov , Thomas D. Wu

Structured pruning methods designed for Large Language Models (LLMs) generally focus on identifying and removing the least important components to optimize model size. However, in this work, we question this prevalent approach by instead…

Machine Learning · Computer Science 2026-02-26 Neha Verma , Kenton Murray , Kevin Duh

During the training of Large Language Models (LLMs), tensor data is periodically "checkpointed" to persistent storage to allow recovery of work done in the event of failure. The volume of data that must be copied during each checkpoint,…

Machine Learning · Computer Science 2025-05-16 Daniel Waddington , Cornel Constantinescu

Lossy compression is one of the most efficient solutions to reduce storage overhead and improve I/O performance for HPC applications. However, existing parallel I/O libraries cannot fully utilize lossy compression to accelerate parallel…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-06-30 Sian Jin , Dingwen Tao , Houjun Tang , Sheng Di , Suren Byna , Zarija Lukic , Franck Cappello

Performance predictability is critical for modern DBMSs because index maintenance can trigger rare but severe I/O spikes. In a B or B+-tree with height H, node split propagation means the cost of a single insert can vary from H + 1 to 3H +…

Databases · Computer Science 2026-03-06 Lu Xing , Walid G. Aref

Recent advancements in large language models (LLMs) have spurred growing interest in automatic theorem proving using Lean4, where effective tree search methods are crucial for navigating the underlying large proof search spaces. While the…

Artificial Intelligence · Computer Science 2025-10-10 Ran Xin , Chenguang Xi , Jie Yang , Feng Chen , Hang Wu , Xia Xiao , Yifan Sun , Shen Zheng , Kai Shen

Memory disaggregation can potentially allow memory-optimized range indexes such as B+-trees to scale beyond one machine while attaining high hardware utilization and low cost. Designing scalable indexes on disaggregated memory, however, is…

Databases · Computer Science 2024-05-24 Baotong Lu , Kaisong Huang , Chieh-Jan Mike Liang , Tianzheng Wang , Eric Lo

The exponential growth in Large Language Model (LLM) deployment has intensified the need for efficient model compression techniques to reduce computational and memory costs. While pruning and quantization have shown promise, their combined…

Computation and Language · Computer Science 2025-05-13 Stanislas Laborde , Martin Cousseau , Antoun Yaacoub , Lionel Prevost

Decision Trees have remained a popular machine learning method for tabular datasets, mainly due to their interpretability. However, they lack the expressiveness needed to handle highly nonlinear or unstructured datasets. Motivated by recent…

Machine Learning · Computer Science 2024-10-30 Dimitris Bertsimas , Lisa Everest , Jiayi Gu , Matthew Peroni , Vasiliki Stoumpou

In this work, we propose a library that enables on a cloud the creation and management of tree data structures from a cloud client. As a proof of concept, we implement a new cloud service CloudTree. With CloudTree, users are able to…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-05-04 Yun Tian , Bojian Xu , Yanqing Ji , Jesse Scholer

The Binary Search Tree (BST) is average in computer science which supports a compact data structure in memory and oneself even conducts a row of quick algorithms, by which people often apply it in dynamical circumstance. Besides these…

Data Structures and Algorithms · Computer Science 2018-10-05 Yong Tan

Bloom filters are widely used data structures that compactly represent sets of elements. Querying a Bloom filter reveals if an element is not included in the underlying set or is included with a certain error rate. This membership testing…

Databases · Computer Science 2022-08-08 Angjela Davitkova , Damjan Gjurovski , Sebastian Michel

In this study, we address the challenge of low-rank model compression in the context of in-memory computing (IMC) architectures. Traditional pruning approaches, while effective in model size reduction, necessitate additional peripheral…

Hardware Architecture · Computer Science 2025-02-13 Kang Eun Jeon , Johnny Rhe , Jong Hwan Ko

Many performance critical systems today must rely on performance enhancements, such as multi-port memories, to keep up with the increasing demand of memory-access capacity. However, the large area footprints and complexity of existing…

Hardware Architecture · Computer Science 2020-01-28 Hardik Jain , Matthew Edwards , Ethan Elenberg , Ankit Singh Rawat , Sriram Vishwanath

The ubiquity and value of tables as semi-structured data across various domains necessitate advanced methods for understanding their complexity and vast amounts of information. Despite the impressive capabilities of large language models…

Computation and Language · Computer Science 2024-11-14 Deyi Ji , Lanyun Zhu , Siqi Gao , Peng Xu , Hongtao Lu , Jieping Ye , Feng Zhao

Deep-learning-based compressor has received interests recently due to much improved compression ratio. However, modern approaches suffer from long execution time. To ease this problem, this paper targets on cutting down the execution time…

Machine Learning · Computer Science 2022-04-04 Yu Mao , Yufei Cui , Tei-Wei Kuo , Chun Jason Xue

Despite rapid advancements, machine learning, particularly deep learning, is hindered by the need for large amounts of labeled data to learn meaningful patterns without overfitting and immense demands for computation and storage, which…

Machine Learning · Computer Science 2025-06-30 Xiaobo Zhao , Aaron Hurst , Panagiotis Karras , Daniel E. Lucani

The quadratic complexity of self-attention constrains Large Language Models (LLMs) in processing long contexts, a capability essential for many advanced applications. Context compression aims to alleviate this computational bottleneck while…

Computation and Language · Computer Science 2025-12-05 Yangning Li , Shaoshen Chen , Yinghui Li , Yankai Chen , Hai-Tao Zheng , Hui Wang , Wenhao Jiang , Philip S. Yu

Non-volatile memory (NVM) technologies are interesting alternatives for building the on-chip Last-Level Cache (LLC). Their advantages, compared to SRAM memory, are higher density and lower static power, but each write operation slightly…

Hardware Architecture · Computer Science 2022-04-08 Carlos Escuin , Pablo Ibañez , Teresa Monreal , Jose M. Llaberia , Victor Viñals

The exponential expansion of context windows in LLMs has unlocked capabilities for long-document understanding but introduced severe bottlenecks in inference latency and information utilization. Existing compression methods often suffer…

Computation and Language · Computer Science 2026-03-23 Zhengpei Hu , Kai Li , Dapeng Fu , Chang Zeng , Yue Li , Yuanhao Tang , Jianqiang Huang
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