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Purpose: To analyze a recently published chest radiography foundation model for the presence of biases that could lead to subgroup performance disparities across biological sex and race. Materials and Methods: This retrospective study used…

Machine Learning · Computer Science 2023-10-03 Ben Glocker , Charles Jones , Melanie Roschewitz , Stefan Winzeck

Standard epidemiological models for COVID-19 employ variants of compartment (SIR) models at local scales, implicitly assuming spatially uniform local mixing. Here, we examine the effect of employing more geographically detailed diffusion…

Student dropout is a persistent concern in Learning Analytics, yet comparative studies frequently evaluate predictive models under heterogeneous protocols, prioritizing discrimination over temporal interpretability and calibration. This…

Machine Learning · Computer Science 2026-05-26 Rafael da Silva , Jeff Eicher , Gregory Longo

Mining 29,000 accounting ratios for t-statistics $> 2.0$ leads to cross-sectional return predictability similar to the peer review process. For both, $\approx50\%$ of predictability remains after the original sample periods. This finding…

General Finance · Quantitative Finance 2026-01-01 Andrew Y. Chen , Alejandro Lopez-Lira , Tom Zimmermann

Performative learning addresses the increasingly pervasive situations in which algorithmic decisions may induce changes in the data distribution as a consequence of their public deployment. We propose a novel view in which these…

Machine Learning · Computer Science 2024-11-05 Edwige Cyffers , Muni Sreenivas Pydi , Jamal Atif , Olivier Cappé

Spatio-temporal epidemic forecasting is critical for public health management, yet existing methods often struggle with insensitivity to weak epidemic signals, over-simplified spatial relations, and unstable parameter estimation. To address…

Machine Learning · Computer Science 2026-05-22 Sijie Ruan , Jinyu Li , Jia Wei , Zenghao Xu , Jie Bao , Junshi Xu , Junyang Qiu , Shuliang Wang , Xiaoxiao Wang , Hanning Yuan

The identification of patient subgroups with comparable event-risk dynamics plays a key role in supporting informed decision-making in clinical research. In such settings, it is important to account for the inherent dependence that arises…

Computation · Statistics 2026-01-13 Alessandra Ragni , Lara Cavinato , Francesca Ieva

Although advances in brain surgery techniques have led to fewer postoperative complications requiring Intensive Care Unit (ICU) monitoring, the routine transfer of patients to the ICU remains the clinical standard, despite its high cost.…

Image and Video Processing · Electrical Eng. & Systems 2024-12-23 Maximilian Fischer , Florian M. Hauptmann , Robin Peretzke , Paul Naser , Peter Neher , Jan-Oliver Neumann , Klaus Maier-Hein

The predictiveness curve is a valuable tool for predictive evaluation, risk stratification, and threshold selection in a target population, given a single biomarker or a prediction model. In the presence of competing risks, regression…

Methodology · Statistics 2025-08-04 Wei Tao , Jing Ning , Wen Li , Wenyaw Chan , Xi Luo , Ruosha Li

We consider a patient risk models which has access to patient features such as vital signs, lab values, and prior history but does not have access to a patient's diagnosis. For example, this occurs in a model deployed at intake time for…

Artificial Intelligence · Computer Science 2023-07-03 Alexander Peysakhovich , Rich Caruana , Yin Aphinyanaphongs

Over the past decade, the use of machine learning (ML) models in healthcare applications has rapidly increased. Despite high performance, modern ML models do not always capture patterns the end user requires. For example, a model may…

Data-centric learning seeks to improve model performance from the perspective of data quality, and has been drawing increasing attention in the machine learning community. Among its key tools, influence functions provide a powerful…

Machine Learning · Computer Science 2025-10-07 Shahriar Kabir Nahin , Wenxiao Xiao , Joshua Liu , Anshuman Chhabra , Hongfu Liu

Disaggregation regression has become an important tool in spatial disease mapping for making fine-scale predictions of disease risk from aggregated response data. By including high resolution covariate information and modelling the data…

Applications · Statistics 2020-05-08 Rohan Arambepola , Tim C D Lucas , Anita K Nandi , Peter W Gething , Ewan Cameron

Transformer-based models have improved predictive modeling on longitudinal electronic health records through large-scale self-supervised pretraining. However, most EHR transformer architectures treat each clinical encounter as an unordered…

Machine Learning · Computer Science 2026-03-17 Krish Tadigotla

Stratification is commonly employed in clinical trials to reduce the chance covariate imbalances and increase the precision of the treatment effect estimate. We propose a general framework for constructing the confidence interval (CI) for a…

Methodology · Statistics 2021-10-26 Yongqiang Tang

Clinical trials often allow patients in the control arm to switch to the treatment arm if their physical conditions are worse than certain tolerance levels. For instance, treatment switching arises in the Concorde clinical trial, which aims…

Applications · Statistics 2023-09-06 Alessandra Mattei , Peng Ding , Veronica Ballerini , Fabrizia Mealli

To increase statistical efficiency in a randomized experiment, researchers often use stratification (i.e., blocking) in the design stage. However, conventional practices of stratification fail to exploit valuable information about the…

Methodology · Statistics 2025-10-28 Zikai Li

The performance figures of modern drift-adaptive malware classifiers appear promising, but does this translate to genuine operational reliability? The standard evaluation paradigm primarily focuses on baseline performance metrics,…

Cryptography and Security · Computer Science 2026-01-22 Alexander Herzog , Aliai Eusebi , Lorenzo Cavallaro

It is widely acknowledged that the predictive performance of clinical prediction models should be studied in patients that were not part of the data in which the model was derived. Out-of-sample performance can be hampered when predictors…

Data corruption, including missing and noisy data, poses significant challenges in real-world machine learning. This study investigates the effects of data corruption on model performance and explores strategies to mitigate these effects…

Machine Learning · Computer Science 2025-05-22 Qi Liu , Wanjing Ma
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