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Given a mixed hyperspectral data set, linear unmixing aims at estimating the reference spectral signatures composing the data - referred to as endmembers - their abundance fractions and their number. In practice, the identified endmembers…

Methodology · Statistics 2016-01-20 Pierre-Antoine Thouvenin , Nicolas Dobigeon , Jean-Yves Tourneret

The ability to extrapolate gene expression dynamics in living single cells requires robust cell segmentation, and one of the challenges is the amorphous or irregularly shaped cell boundaries. To address this issue, we modified the U-Net…

Quantitative Methods · Quantitative Biology 2020-01-17 Nanyan Zhu , Chen Liu , Zakary S. Singer , Tal Danino , Andrew F. Laine , Jia Guo

Motivation: The discovery of relationships between gene expression measurements and phenotypic responses is hampered by both computational and statistical impediments. Conventional statistical methods are less than ideal because they either…

Methodology · Statistics 2019-07-16 Lei Ding , Daniel J. McDonald

In learning theory, a standard assumption is that the data is generated from a finite mixture model. But what happens when the number of components is not known in advance? The problem of estimating the number of components, also called…

Data Structures and Algorithms · Computer Science 2023-04-25 Jerry Li , Allen Liu , Ankur Moitra

Discrete mixture models provide a well-known basis for effective clustering algorithms, although technical challenges have limited their scope. In the context of gene-expression data analysis, a model is presented that mixes over a finite…

Methodology · Statistics 2012-11-12 Michael A. Newton , Lisa M. Chung

Randomized neural networks for representation learning have consistently achieved prominent results in texture recognition tasks, effectively combining the advantages of both traditional techniques and learning-based approaches. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-06 Ricardo T. Fares , Lucas C. Ribas

The clustering of bounded data presents unique challenges in statistical analysis due to the constraints imposed on the data values. This paper introduces a novel method for model-based clustering specifically designed for bounded data.…

Methodology · Statistics 2025-05-16 Luca Scrucca

Mixup, which creates synthetic training instances by linearly interpolating random sample pairs, is a simple and yet effective regularization technique to boost the performance of deep models trained with SGD. In this work, we report a…

Machine Learning · Computer Science 2023-03-03 Zixuan Liu , Ziqiao Wang , Hongyu Guo , Yongyi Mao

Variations in complex traits are influenced by multiple genetic variants, environmental risk factors, and their interactions. Though substantial progress has been made in identifying single genetic variants associated with complex traits,…

Genomics · Quantitative Biology 2025-08-22 Ming Li , Ruo-Sin Peng , Changshuai Wei , Qing Lu

Ensemble models refer to methods that combine a typically large number of classifiers into a compound prediction. The output of an ensemble method is the result of fitting a base-learning algorithm to a given data set, and obtaining diverse…

Machine Learning · Statistics 2019-06-10 Waldyn Martinez

We present a coherent Bayesian framework for selection of the most likely model from the five genetic models (genotypic, additive, dominant, co-dominant, and recessive) commonly used in genetic association studies. The approach uses a…

Methodology · Statistics 2015-04-22 Harold Bae , Thomas Perls , Martin Steinberg , Paola Sebastiani

Multiplicative noise models are often used instead of additive noise models in cases in which the noise variance depends on the state. Furthermore, when Poisson distributions with relatively small counts are approximated with normal…

Optimization and Control · Mathematics 2018-06-08 Ruanui Nicholson , Jari P. Kaipio

Inferring concerted changes among biological traits along an evolutionary history remains an important yet challenging problem. Besides adjusting for spurious correlation induced from the shared history, the task also requires sufficient…

Neutrino mixing sum rules are common to a large class of models based on the (discrete) symmetry approach to lepton flavour. In this approach the neutrino mixing matrix $U$ is assumed to have an underlying approximate symmetry form…

High Energy Physics - Phenomenology · Physics 2016-11-28 J. Gehrlein , S. T. Petcov , M. Spinrath , A. V. Titov

Bayesian Model Mixing (BMM) is a statistical technique that can be used to combine models that are predictive in different input domains into a composite distribution that has improved predictive power over the entire input space. We…

Nuclear Theory · Physics 2023-11-02 A. C. Semposki , R. J. Furnstahl , D. R. Phillips

Prior work has shown that Visual Recognition datasets frequently underrepresent bias groups $B$ (\eg Female) within class labels $Y$ (\eg Programmers). This dataset bias can lead to models that learn spurious correlations between class…

Computer Vision and Pattern Recognition · Computer Science 2023-04-28 Maan Qraitem , Kate Saenko , Bryan A. Plummer

One of the challenges in hyperspectral data analysis is the presence of mixed pixels. Mixed pixels are the result of low spatial resolution of hyperspectral sensors. Spectral unmixing methods decompose a mixed pixel into a set of endmembers…

Computer Vision and Pattern Recognition · Computer Science 2015-06-05 Roozbeh Rajabi , Hassan Ghassemian

In this paper, we study Bayesian approach for solving large scale linear inverse problems arising in various scientific and engineering fields. We propose a fused $L_{1/2}$ prior with edge-preserving and sparsity-promoting properties and…

Computation · Statistics 2025-12-17 Xiongwen Ke , Yanan Fan , Qingping Zhou

Monitoring the distribution of microfossils in stratigraphic successions is an essential tool for biostratigraphic, evolutionary and paleoecologic/paleoceanographic studies. To estimate the relative abundance (%) of a given species, it is…

Quantitative Methods · Quantitative Biology 2018-05-14 Ali T. Haidar , Abbas Al-Hakim , Zhiyi Zhang

In this article, we introduce finite mixture models (FMMs) renowned for capturing population heterogeneity. Our focus lies in establishing stochastic comparisons between two arithmetic (finite) mixture models, employing the vector…

Statistics Theory · Mathematics 2024-12-16 Raju Bhakta , Nuria Torrado , Sangita Das , Suchandan Kayal