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Related papers: Quantum Molecular Unfolding

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Numerous molecular systems, including solutions, proteins, and composite materials, can be modeled using mixed-resolution representations, of which the quantum mechanics/molecular mechanics (QM/MM) approach has become the most widely used.…

Chemical Physics · Physics 2018-01-17 Anton V. Sinitskiy , Gregory A. Voth

A quantum compiling algorithm is an algorithm for decomposing ("compiling") an arbitrary unitary matrix into a sequence of elementary operations (SEO). Suppose $U_{in}$ is an $\nb$-bit unstructured unitary matrix (a unitary matrix with no…

Quantum Physics · Physics 2007-05-23 Robert R. Tucci

Machine learning methods have been used to accelerate the molecule optimization process. However, efficient search for optimized molecules satisfying several properties with scarce labeled data remains a challenge for machine learning…

Biomolecules · Quantitative Biology 2022-12-20 Xin Xia , Yansen Su , Chunhou Zheng , Xiangxiang Zeng

Artificial magnetic molecules can contribute to progressing towards large scale quantum computation by: a) integrating multiple quantum resources and b) reducing the computational costs of some applications. Chemical design, guided by…

Quantum Physics · Physics 2021-06-30 S. Carretta , D. Zueco , A. Chiesa , Á. Gómez-León , F. Luis

Massive arrays deployed in millimeter-wave systems enable high angular resolution performance, which in turn facilitates sub-meter localization services. Albeit suboptimal, up to now the most popular localization approach has been based on…

Signal Processing · Electrical Eng. & Systems 2023-02-07 Wenzhe Fan , Shengheng Liu , Chunguo Li , Yongming Huang

Machine learning has the potential to automate molecular design and drastically accelerate the discovery of new functional compounds. Towards this goal, generative models and reinforcement learning (RL) using string and graph…

Machine Learning · Computer Science 2022-02-02 Daniel Flam-Shepherd , Alexander Zhigalin , Alán Aspuru-Guzik

Quantum computing has emerged as a powerful tool to efficiently solve computational challenges, particularly in simulation and optimisation. However, hardware limitations prevent quantum computers from achieving the full theoretical…

Emerging Technologies · Computer Science 2025-05-01 Hugo Araujo , Xinyi Wang , Mohammad Mousavi , Shaukat Ali

This paper presents a new hybrid classical-quantum approach to solve Mixed Integer Linear Programming (MILP) using neutral atom quantum computations. We apply Benders decomposition (BD) to segment MILPs into a master problem (MP) and a…

Quantum Physics · Physics 2024-07-17 M. Yassine Naghmouchi , Wesley da Silva Coelho

In recent years, machine learning (ML) methods have emerged as promising alternatives for molecular docking, offering the potential for high accuracy without incurring prohibitive computational costs. However, recent studies have indicated…

Biomolecules · Quantitative Biology 2024-05-21 Eric Alcaide , Zhifeng Gao , Guolin Ke , Yaqi Li , Linfeng Zhang , Hang Zheng , Gengmo Zhou

Quantum annealers are an alternative approach to quantum computing which make use of the adiabatic theorem to efficiently find the ground state of a physically realizable Hamiltonian. Such devices are currently commercially available and…

Quantum Physics · Physics 2021-02-24 Justin Copenhaver , Adam Wasserman , Birgit Wehefritz-Kaufmann

Critical decision-making issues in science, engineering, and industry are based on combinatorial optimization; however, its application is inherently limited by the NP-hard nature of the problem. A specialized paradigm of analogue quantum…

Quantum Physics · Physics 2026-02-04 Rudraksh Sharma , Ravi Katukam , Arjun Nagulapally

This paper presents a generalization of a method allowing the transformation of the Elliptic Curve Discrete Logarithm Problem (ECDLP) over prime fields to the Quadratic Unconstrained Binary Optimization (QUBO) problem. The original method…

Cryptography and Security · Computer Science 2024-10-14 Łukasz Dzierzkowski

The prospect of quantum solutions for complicated optimization problems is contingent on mapping the original problem onto a tractable quantum energy landscape, e.g. an Ising-type Hamiltonian. Subsequently, techniques like adiabatic…

Quantum Physics · Physics 2025-10-17 Sebastian Egginger , Kristina Kirova , Sonja Bruckner , Stefan Hillmich , Richard Kueng

Quantum computing is emerging as a new computing resource that could be superior to conventional computing for certain classes of optimization problems. However, in principle, most existing approaches to quantum optimization are intended to…

Optimization and Control · Mathematics 2022-01-21 Chin-Yao Chang , Eric Jones , Yiyun Yao , Peter Graf , Rishabh Jain

This paper explores the applications of quantum annealing (QA) and classical simulated annealing (SA) to a suite of combinatorial optimization problems in machine learning, namely feature selection, instance selection, and clustering. We…

Quantum Physics · Physics 2025-07-22 Chloe Pomeroy , Aleksandar Pramov , Karishma Thakrar , Lakshmi Yendapalli

Diatomic polar molecules are one of the most promising platforms of quantum computing due to their rich internal states and large electric dipole moments. Here, we propose entangling rotational states of adjacent polar molecules via a…

Atomic Physics · Physics 2021-05-07 Eunmi Chae

Quantum annealing may provide advantages over simulated annealing on solving some problems such as Kth order binary optimization problem. No feasible architecture exists to implement the high-order optimization problem (K > 2) on current…

Quantum Physics · Physics 2016-05-13 Yong-Chao Tang , Guo-Xing Miao

Despite being the main tool to visualize molecules at the atomic scale, AFM with CO-functionalized metal tips is unable to chemically identify the observed molecules. Here we present a strategy to address this challenging task using deep…

Materials Science · Physics 2025-09-03 Jaime Carracedo-Cosme , Carlos Romero-Muñiz , Pablo Pou , Rubén Pérez

Density matrix downfolding (DMD) is a technique for regressing low-energy effective Hamiltonians from quantum many-body Hamiltonians. One limiting factor in the accuracy of classical implementations of DMD is the presence of…

Brief description on the state of the art of some local optimization methods: Quantum annealing Quantum annealing (also known as alloy, crystallization or tempering) is analogous to simulated annealing but in substitution of thermal…

Data Structures and Algorithms · Computer Science 2014-04-10 Alfonso de la Fuente Ruiz