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Segmentation of Multiple Sclerosis (MS) lesions is a challenging problem. Several deep-learning-based methods have been proposed in recent years. However, most methods tend to be static, that is, a single model trained on a large,…

Multiple sclerosis is an inflammatory autoimmune demyelinating disease that is characterized by lesions in the central nervous system. Typically, magnetic resonance imaging (MRI) is used for tracking disease progression. Automatic image…

Universal lesion detection in computed tomography (CT) images is an important yet challenging task due to the large variations in lesion type, size, shape, and appearance. Considering that data in clinical routine (such as the DeepLesion…

Separating overlapped nuclei is a major challenge in histopathology image analysis. Recently published approaches have achieved promising overall performance on public datasets; however, their performance in segmenting overlapped nuclei are…

Objective: This work addresses two key problems of skin lesion classification. The first problem is the effective use of high-resolution images with pretrained standard architectures for image classification. The second problem is the high…

The detection of new multiple sclerosis (MS) lesions is an important marker of the evolution of the disease. The applicability of learning-based methods could automate this task efficiently. However, the lack of annotated longitudinal data…

Segmenting small lesions in medical images remains notoriously difficult. Most prior work tackles this challenge by either designing better architectures, loss functions, or data augmentation schemes; and collecting more labeled data. We…

Longitudinal imaging forms an essential component in the management and follow-up of many medical conditions. The presence of lesion changes on serial imaging can have significant impact on clinical decision making, highlighting the…

A major challenge in stroke research and stroke recovery predictions is the determination of a stroke lesion's extent and its impact on relevant brain systems. Manual segmentation of stroke lesions from 3D magnetic resonance (MR) imaging…

Radiologists use various imaging modalities to aid in different tasks like diagnosis of disease, lesion visualization, surgical planning and prognostic evaluation. Most of these tasks rely on the the accurate delineation of the anatomical…

Accurate segmentation of skin lesions within dermoscopic images plays a crucial role in the timely identification of skin cancer for computer-aided diagnosis on mobile platforms. However, varying shapes of the lesions, lack of defined…

In recent years, several convolutional neural network (CNN) methods have been proposed for the automated white matter lesion segmentation of multiple sclerosis (MS) patient images, due to their superior performance compared with those of…

Automatic retinal layer segmentation with medical images, such as optical coherence tomography (OCT) images, serves as an important tool for diagnosing ophthalmic diseases. However, it is challenging to achieve accurate segmentation due to…

Skin cancer is among the most common cancer types. Dermoscopic image analysis improves the diagnostic accuracy for detection of malignant melanoma and other pigmented skin lesions when compared to unaided visual inspection. Hence,…

Efficient and accurate whole-brain lesion segmentation remains a challenge in medical image analysis. In this work, we revisit MeshNet, a parameter-efficient segmentation model, and introduce a novel multi-scale dilation pattern with an…

Deep learning (DL) networks have recently been shown to outperform other segmentation methods on various public, medical-image challenge datasets [3,11,16], especially for large pathologies. However, in the context of diseases such as…

Deep convolutional neural networks have driven substantial advancements in the automatic understanding of images. Requiring a large collection of images and their associated annotations is one of the main bottlenecks limiting the adoption…

Deep learning methods have contributed substantially to the rapid advancement of medical image segmentation, the quality of which relies on the suitable design of loss functions. Popular loss functions, including the cross-entropy and dice…

The accuracy of deep learning methods for two foundational tasks in medical image analysis -- detection and segmentation -- can suffer from class imbalance. We propose a `switching loss' function that adaptively shifts the emphasis between…

Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic…