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A common challenge in real-time operations is deciding whether to re-solve an optimization problem or continue using an existing solution. While modern data platforms may collect information at high frequencies, many real-time operations…

Machine Learning · Computer Science 2025-09-30 Rui Ai , Hugo De Oliveira Barbalho , Sirui Li , Alexei Robsky , David Simchi-Levi , Ishai Menache

Predictive simulations of complex systems are essential for applications ranging from weather forecasting to drug design. The veracity of these predictions hinges on their capacity to capture the effective system dynamics. Massively…

Computational Physics · Physics 2021-10-20 Pantelis R. Vlachas , Georgios Arampatzis , Caroline Uhler , Petros Koumoutsakos

Lead optimization in drug discovery requires efficiently navigating vast chemical space through iterative cycles to enhance molecular properties while preserving structural similarity to the original lead compound. Despite recent advances,…

Machine Learning · Computer Science 2025-09-29 Ziqing Wang , Yibo Wen , William Pattie , Xiao Luo , Weimin Wu , Jerry Yao-Chieh Hu , Abhishek Pandey , Han Liu , Kaize Ding

This paper presents an optimization-based receding horizon trajectory planning algorithm for dynamical systems operating in unstructured and cluttered environments. The proposed approach is a two-step procedure that uses a motion planning…

Optimization and Control · Mathematics 2019-12-12 Kristoffer Bergman , Oskar Ljungqvist , Torkel Glad , Daniel Axehill

Large language models (LLMs) have catalyzed an upsurge in automatic code generation, garnering significant attention for register transfer level (RTL) code generation. Despite the potential of RTL code generation with natural language, it…

Hardware Architecture · Computer Science 2024-08-14 Chenwei Xiong , Cheng Liu , Huawei Li , Xiaowei Li

Writing high-performance code requires significant expertise in the programming language, compiler optimizations, and hardware knowledge. This often leads to poor productivity and portability and is inconvenient for a non-programmer…

Performance · Computer Science 2020-09-01 Ajitesh Srivastava , Naifeng Zhang , Rajgopal Kannan , Viktor K. Prasanna

While polyhedral compilers have shown success in implementing advanced code transformations, they still face challenges in selecting the ones that lead to the most profitable speedups. This has motivated the use of machine learning based…

Code super-optimization is the task of transforming any given program to a more efficient version while preserving its input-output behaviour. In some sense, it is similar to the paraphrase problem from natural language processing where the…

Machine Learning · Computer Science 2017-06-29 Rudy Bunel , Alban Desmaison , M. Pawan Kumar , Philip H. S. Torr , Pushmeet Kohli

Pipelining between data loading and computation is a critical tensor program optimization for GPUs. In order to unleash the high performance of latest GPUs, we must perform a synergetic optimization of multi-stage pipelining across the…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-05-09 Guyue Huang , Yang Bai , Liu Liu , Yuke Wang , Bei Yu , Yufei Ding , Yuan Xie

Many production lines require active control mechanisms, such as adaptive routing, worker reallocation, and rescheduling, to maintain optimal performance. However, designing these control systems is challenging for various reasons, and…

Machine Learning · Computer Science 2025-05-13 Kai Müller , Martin Wenzel , Tobias Windisch

Machine learning-based analysis of medical images often faces several hurdles, such as the lack of training data, the curse of dimensionality problem, and the generalization issues. One of the main difficulties is that there exists…

Machine Learning · Computer Science 2019-07-29 Chang Min Hyun , Kang Cheol Kim , Hyun Cheol Cho , Jae Kyu Choi , Jin Keun Seo

Pipeline is a fundamental parallel programming pattern. Mainstream pipeline programming frameworks count on data abstractions to perform pipeline scheduling. This design is convenient for data-centric pipeline applications but inefficient…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-02-03 Cheng-Hsiang Chiu , Tsung-Wei Huang , Zizheng Guo , Yibo Lin

Topology optimization is widely used by engineers during the initial product development process to get a first possible geometry design. The state-of-the-art is the iterative calculation, which requires both time and computational power.…

Machine Learning · Computer Science 2021-09-30 Alex Halle , L. Flavio Campanile , Alexander Hasse

Traditional preference tuning methods for LLMs/Visual Generative Models often rely solely on reward model labeling, which can be opaque, offer limited insights into the rationale behind preferences, and are prone to issues such as reward…

Machine Learning · Computer Science 2026-01-13 Hanyang Zhao , Haoxian Chen , Yucheng Guo , Genta Indra Winata , Tingting Ou , Ziyu Huang , David D. Yao , Wenpin Tang

Recent advances in multimodal large language models (MLLMs) have enabled richer perceptual grounding for code policy generation in embodied agents. However, most existing systems lack effective mechanisms to adaptively monitor policy…

Language Model Programs, i.e. sophisticated pipelines of modular language model (LM) calls, are increasingly advancing NLP tasks, but they require crafting prompts that are jointly effective for all modules. We study prompt optimization for…

Computation and Language · Computer Science 2024-10-08 Krista Opsahl-Ong , Michael J Ryan , Josh Purtell , David Broman , Christopher Potts , Matei Zaharia , Omar Khattab

This paper presents a hybrid CPU-GPU framework for solving combinatorial scheduling problems formulated as Integer Linear Programming (ILP). While scheduling underpins many optimization tasks in computing systems, solving these problems…

Machine Learning · Computer Science 2026-04-01 Mingju Liu , Jiaqi Yin , Alvaro Velasquez , Cunxi Yu

Algorithm design is a laborious process and often requires many iterations of ideation and validation. In this paper, we explore automating algorithm design and present a method to learn an optimization algorithm, which we believe to be the…

Machine Learning · Computer Science 2016-06-07 Ke Li , Jitendra Malik

Register Transfer Level(RTL) code optimization is crucial for achieving high performance and low power consumption in digital circuit design. However, traditional optimization methods often rely on manual tuning and heuristics, which can be…

Software Engineering · Computer Science 2025-07-23 Zhihao Xu , Bixin Li , Lulu Wang

Resource-intensive computations are a major factor that limits the effectiveness of automated machine learning solutions. In the paper, we propose a modular approach that can be used to increase the quality of evolutionary optimization for…

Machine Learning · Computer Science 2023-01-13 Nikolay O. Nikitin , Sergey Teryoshkin , Valerii Pokrovskii , Sergey Pakulin , Denis Nasonov