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We introduce $\texttt{PairFlow}$, a lightweight preprocessing step for training Discrete Flow Models (DFMs) to achieve few-step sampling without requiring a pretrained teacher. DFMs have recently emerged as a new class of generative models…

Machine Learning · Computer Science 2026-05-26 Mingue Park , Jisung Hwang , Seungwoo Yoo , Kyeongmin Yeo , Minhyuk Sung

Precise manipulation of fluids and objects on the micro scale is seldom a simple task, but nevertheless crucial for many applications in life sciences and chemical engineering. We present a microfluidic chip fabricated in silicon-glass,…

We present efficient deep learning techniques for approximating flow and transport equations for both single phase and two-phase flow problems. The proposed methods take advantages of the sparsity structures in the underlying discrete…

Numerical Analysis · Mathematics 2020-01-08 Yating Wang , Guang Lin

We consider a design problem where experimental conditions (design points $X_i$) are presented in the form of a sequence of i.i.d.\ random variables, generated with an unknown probability measure $\mu$, and only a given proportion…

Methodology · Statistics 2020-08-05 Luc Pronzato , HaiYing Wang

Accurate subsurface reservoir pressure control is extremely challenging due to geological heterogeneity and multiphase fluid-flow dynamics. Predicting behavior in this setting relies on high-fidelity physics-based simulations that are…

Machine Learning · Computer Science 2025-08-28 Harun Ur Rashid , Aleksandra Pachalieva , Daniel O'Malley

Reconstructing high-fidelity flow fields from low-fidelity observations is a central problem in scientific machine learning, yet recent diffusion and flow-matching models typically rely on iterative sampling, making them costly for…

Machine Learning · Computer Science 2026-05-08 Sicheng Ma , Tianyue Yang , Xiuzhe Wu , Xiao Xue

Diffusion and flow-matching models achieve remarkable generative performance but at the cost of many sampling steps, this slows inference and limits applicability to time-critical tasks. The ReFlow procedure can accelerate sampling by…

Machine Learning · Computer Science 2024-10-11 Beomsu Kim , Yu-Guan Hsieh , Michal Klein , Marco Cuturi , Jong Chul Ye , Bahjat Kawar , James Thornton

This paper presents several test cases intended to be benchmarks for numerical schemes for single-phase fluid flow in fractured porous media. A number of solution strategies are compared, including a vertex and a cell-centered finite volume…

Diffusion models have shown remarkable performance in generation problems over various domains including images, videos, text, and audio. A practical bottleneck of diffusion models is their sampling speed, due to the repeated evaluation of…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Taehong Moon , Moonseok Choi , EungGu Yun , Jongmin Yoon , Gayoung Lee , Jaewoong Cho , Juho Lee

Technologies for sequencing (reading) and synthesizing (writing) DNA have progressed on a Moore's law-like trajectory over the last three decades. This has motivated the idea of using DNA for data storage. Theoretically, DNA-based storage…

Emerging Technologies · Computer Science 2023-07-07 Ajay Manicka , Andrew Stephan , Sriram Chari , Gemma Mendonsa , Peyton Okubo , John Stolzberg-Schray , Anil Reddy , Marc Riedel

Label-free detecting multiple analytes in a high-throughput fashion has been one of the long-sought goals in biosensing applications. Yet, for all-optical approaches, interfacing state-of-the-art label-free techniques with microfluidics…

Quantitative Methods · Quantitative Biology 2023-08-14 Alexia Stollmann , Jose Garcia-Guirado , Jae-Sang Hong , Hyungsoon Im , Hakho Lee , Jaime Ortega Arroyo , Romain Quidant

Machine learning models, and deep neural networks in particular, are increasingly deployed in risk-sensitive domains such as healthcare, environmental forecasting, and finance, where reliable quantification of predictive uncertainty is…

Machine Learning · Computer Science 2026-04-07 Asena Karolin Özdemir , Lars H. Heyen , Arvid Weyrauch , Achim Streit , Markus Götz , Charlotte Debus

A general method for obtaining highly efficient factorial designs of relatively small sizes is developed for cDNA microarray experiments. The method allows the main effects and interactions of successive orders to be of possibly unequal…

Methodology · Statistics 2012-07-31 Runchu Zhang , Rahul Mukerjee

Discrete diffusion models (DDMs) have shown powerful generation ability for discrete data modalities like text and molecules. However, their practical application is hindered by inefficient sampling, requiring a large number of sampling…

Machine Learning · Computer Science 2025-09-25 Feiyang Fu , Tongxian Guo , Zhaoqiang Liu

The use of asynchronous design approaches to construct digital signal processing (DSP) systems is a rapidly growing research area driven by a wide range of emerging energy constrained applications such as wireless sensor network, portable…

Hardware Architecture · Computer Science 2016-03-16 Basel Halak , Hsien-Chih Chiu

Selection of solution concentrations and flow rates for the fabrication of microfibers using a microfluidic device is a largely empirical endeavor of trial-and-error, largely due to the difficulty of modeling such a multiphysics process.…

Experimental science is increasingly driven by instruments that produce vast volumes of data and thus a need to manage, compute, describe, and index this data. High performance and distributed computing provide the means of addressing the…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-03-12 Jim Pruyne , Valerie Hayot-Sasson , Weijian Zheng , Ryan Chard , Justin M. Wozniak , Tekin Bicer , Kyle Chard , Ian T. Foster

We propose SymDiff, a method for constructing equivariant diffusion models using the framework of stochastic symmetrisation. SymDiff resembles a learned data augmentation that is deployed at sampling time, and is lightweight,…

Machine Learning · Computer Science 2025-03-04 Leo Zhang , Kianoosh Ashouritaklimi , Yee Whye Teh , Rob Cornish

Computational Fluid Dynamics (CFD) simulations are a very important tool for many industrial applications, such as aerodynamic optimization of engineering designs like cars shapes, airplanes parts etc. The output of such simulations, in…

Computer Vision and Pattern Recognition · Computer Science 2021-03-12 Theodoros Georgiou , Sebastian Schmitt , Thomas Bäck , Nan Pu , Wei Chen , Michael Lew

In this work, we introduce the novel technique of in-chip drop on demand, which consists in dispensing picoliter to nanoliter drops on demand directly in the liquid-filled channels of a polymer microfluidic chip, at frequencies up to 2.5…

Quantitative Methods · Quantitative Biology 2009-12-16 Jie Xu , Daniel Attinger