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Molecular property prediction integrates quantum chemistry, cheminformatics, and deep learning to connect molecular structure with physicochemical and biological behavior. This survey traces four complementary paradigms, including Quantum,…

Deep Learning (DL) has attracted a lot of attention for its ability to reach state-of-the-art performance in many machine learning tasks. The core principle of DL methods consists in training composite architectures in an end-to-end…

Machine Learning · Computer Science 2020-11-17 Carlos Lassance , Vincent Gripon , Antonio Ortega

This article surveys the growing interest in utilizing Deep Learning (DL) as a powerful tool to address challenging problems in earthquake engineering. Despite decades of advancement in domain knowledge, issues such as uncertainty in…

Machine Learning · Computer Science 2024-05-16 Yazhou Xie

Although Deep Learning (DL) has achieved success in complex Artificial Intelligence (AI) tasks, it suffers from various notorious problems (e.g., feature redundancy, and vanishing or exploding gradients), since updating parameters in…

Machine Learning · Computer Science 2023-02-17 Yanhong Fei , Xian Wei , Yingjie Liu , Zhengyu Li , Mingsong Chen

Since the concept of Deep Learning (DL) was formally proposed in 2006, it had a major impact on academic research and industry. Nowadays, DL provides an unprecedented way to analyze and process data with demonstrated great results in…

Medical Physics · Physics 2020-04-06 Dicheng Chen , Zi Wang , Di Guo , Vladislav Orekhov , Xiaobo Qu

Researchers have now achieved great success on dealing with 2D images using deep learning. In recent years, 3D computer vision and Geometry Deep Learning gain more and more attention. Many advanced techniques for 3D shapes have been…

Graphics · Computer Science 2020-04-16 Yun-Peng Xiao , Yu-Kun Lai , Fang-Lue Zhang , Chunpeng Li , Lin Gao

The ability to transform location-centric geospatial data into meaningful computational representations has become fundamental to modern spatial analysis and decision-making. Geospatial Representation Learning (GRL), the process of…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 Xixuan Hao , Yutian Jiang , Xingchen Zou , Jiabo Liu , Yifang Yin , Song Gao , Flora Salim , Tianrui Li , Yuxuan Liang

Deep learning has revolutionized biomedical research by providing sophisticated methods to handle complex, high-dimensional data. Multimodal deep learning (MDL) further enhances this capability by integrating diverse data types such as…

Machine Learning · Computer Science 2026-03-13 Valerio Guarrasi , Fatih Aksu , Camillo Maria Caruso , Francesco Di Feola , Aurora Rofena , Filippo Ruffini , Paolo Soda

We develop and test new machine learning strategies for accelerating molecular crystal structure ranking and crystal property prediction using tools from geometric deep learning on molecular graphs. Leveraging developments in graph-based…

Materials Science · Physics 2024-07-29 Michael Kilgour , Jutta Rogal , Mark Tuckerman

Deep learning (DL) has recently emerged as a pivotal technology for enhancing magnetic resonance imaging (MRI), a critical tool in diagnostic radiology. This review paper provides a comprehensive overview of recent advances in DL for MRI…

Machine Learning · Computer Science 2024-04-25 Reinhard Heckel , Mathews Jacob , Akshay Chaudhari , Or Perlman , Efrat Shimron

Deep learning for molecular science has so far mainly focused on 2D molecular graphs. Recently, however, there has been work to extend it to 3D molecular geometry, due to its scientific significance and critical importance in real-world…

Machine Learning · Computer Science 2022-07-19 Daniel T. Chang

We present a three-dimensional graph convolutional network (3DGCN), which predicts molecular properties and biochemical activities, based on 3D molecular graph. In the 3DGCN, graph convolution is unified with learning operations on the…

Machine Learning · Computer Science 2019-08-08 Hyeoncheol Cho , Insung S. Choi

Although deep learning (DL) has already become a state-of-the-art technology for various data processing tasks, data security and computational overload problems often arise due to their high data and computational power dependency. To…

Quantum Physics · Physics 2022-04-08 Yunseok Kwak , Won Joon Yun , Jae Pyoung Kim , Hyunhee Cho , Minseok Choi , Soyi Jung , Joongheon Kim

Geometric deep learning models, which incorporate the relevant molecular symmetries within the neural network architecture, have considerably improved the accuracy and data efficiency of predictions of molecular properties. Building on this…

This paper investigates the foundations of deep learning through insight of geometry, algebra and differential calculus. At is core, artificial intelligence relies on assumption that data and its intrinsic structure can be embedded into…

Differential Geometry · Mathematics 2025-10-22 Tsemo Aristide

The increased availability of data and computing resources has enabled researchers to successfully adopt machine learning (ML) techniques and make significant contributions in several engineering areas. ML and in particular deep learning…

Machine Learning · Computer Science 2025-02-10 Nunzio A. Letizia

Ground-state 3D geometries of molecules are essential for many molecular analysis tasks. Modern quantum mechanical methods can compute accurate 3D geometries but are computationally prohibitive. Currently, an efficient alternative to…

Chemical Physics · Physics 2023-05-24 Zhao Xu , Yaochen Xie , Youzhi Luo , Xuan Zhang , Xinyi Xu , Meng Liu , Kaleb Dickerson , Cheng Deng , Maho Nakata , Shuiwang Ji

Deep learning has achieved a remarkable performance breakthrough in several fields, most notably in speech recognition, natural language processing, and computer vision. In particular, convolutional neural network (CNN) architectures…

Computer Vision and Pattern Recognition · Computer Science 2016-12-08 Federico Monti , Davide Boscaini , Jonathan Masci , Emanuele Rodolà , Jan Svoboda , Michael M. Bronstein

Molecular property prediction (MPP) is a fundamental but challenging task in the computer-aided drug discovery process. More and more recent works employ different graph-based models for MPP, which have made considerable progress in…

Machine Learning · Computer Science 2023-12-29 Bangyi Zhao , Weixia Xu , Jihong Guan , Shuigeng Zhou

A graph neural network (GNN) is a good choice for predicting the chemical properties of molecules. Compared with other deep networks, however, the current performance of a GNN is limited owing to the "curse of depth." Inspired by…

Machine Learning · Computer Science 2020-08-19 Katsuhiko Ishiguro , Kenta Oono , Kohei Hayashi