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Deformable image registration is a fundamental problem in the field of medical image analysis. During the last years, we have witnessed the advent of deep learning-based image registration methods which achieve state-of-the-art performance,…

Image and Video Processing · Electrical Eng. & Systems 2020-02-03 Lucas Mansilla , Diego H. Milone , Enzo Ferrante

Understanding internal representations of neural models is a core interest of mechanistic interpretability. Due to its large dimensionality, the representation space can encode various aspects about inputs. To what extent are different…

Machine Learning · Computer Science 2026-05-15 Xinting Huang , Michael Hahn

Clinical decision making from magnetic resonance imaging (MRI) combines complementary information from multiple MRI sequences (defined as 'modalities'). MRI image registration aims to geometrically 'pair' diagnoses from different…

Image and Video Processing · Electrical Eng. & Systems 2023-08-07 Chengjia Wang , Giorgos Papanastasiou

Deep learning methods have recently made notable advances in the tasks of classification and representation learning. These tasks are important for brain imaging and neuroscience discovery, making the methods attractive for porting to a…

Neural and Evolutionary Computing · Computer Science 2014-02-20 Sergey M. Plis , Devon R. Hjelm , Ruslan Salakhutdinov , Vince D. Calhoun

Deep generative models like variational autoencoders approximate the intrinsic geometry of high dimensional data manifolds by learning low-dimensional latent-space variables and an embedding function. The geometric properties of these…

Computer Vision and Pattern Recognition · Computer Science 2019-02-20 Ankita Shukla , Shagun Uppal , Sarthak Bhagat , Saket Anand , Pavan Turaga

Registration is the process that computes the transformation that aligns sets of data. Commonly, a registration process can be divided into four main steps: target selection, feature extraction, feature matching, and transform computation…

Computer Vision and Pattern Recognition · Computer Science 2020-10-29 Victor Villena-Martinez , Sergiu Oprea , Marcelo Saval-Calvo , Jorge Azorin-Lopez , Andres Fuster-Guillo , Robert B. Fisher

Medical image registration is a challenging task involving the estimation of spatial transformations to establish anatomical correspondence between pairs or groups of images. Recently, deep learning-based image registration methods have…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Xiang Chen , Yan Xia , Nishant Ravikumar , Alejandro F Frangi

Cortical surface registration is a fundamental tool for neuroimaging analysis that has been shown to improve the alignment of functional regions relative to volumetric approaches. Classically, image registration is performed by optimizing a…

Computer Vision and Pattern Recognition · Computer Science 2022-03-25 Mohamed A. Suliman , Logan Z. J. Williams , Abdulah Fawaz , Emma C. Robinson

Diffeomorphic image registration, offering smooth transformation and topology preservation, is required in many medical image analysis tasks.Traditional methods impose certain modeling constraints on the space of admissible transformations…

Computer Vision and Pattern Recognition · Computer Science 2022-11-03 Kun Han , Shanlin sun , Xiangyi Yan , Chenyu You , Hao Tang , Junayed Naushad , Haoyu Ma , Deying Kong , Xiaohui Xie

Recently, with the significant developments in deep learning techniques, solving underdetermined inverse problems has become one of the major concerns in the medical imaging domain. Typical examples include undersampled magnetic resonance…

Image and Video Processing · Electrical Eng. & Systems 2020-06-29 Chang Min Hyun , Seong Hyeon Baek , Mingyu Lee , Sung Min Lee , Jin Keun Seo

Multimodal registration is a challenging problem in medical imaging due the high variability of tissue appearance under different imaging modalities. The crucial component here is the choice of the right similarity measure. We make a step…

Computer Vision and Pattern Recognition · Computer Science 2016-09-20 Martin Simonovsky , Benjamín Gutiérrez-Becker , Diana Mateus , Nassir Navab , Nikos Komodakis

Neural networks have greatly boosted performance in computer vision by learning powerful representations of input data. The drawback of end-to-end training for maximal overall performance are black-box models whose hidden representations…

Computer Vision and Pattern Recognition · Computer Science 2020-04-29 Patrick Esser , Robin Rombach , Björn Ommer

Data-driven deep learning approaches to image registration can be less accurate than conventional iterative approaches, especially when training data is limited. To address this whilst retaining the fast inference speed of deep learning, we…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Xi Jia , Alexander Thorley , Wei Chen , Huaqi Qiu , Linlin Shen , Iain B Styles , Hyung Jin Chang , Ales Leonardis , Antonio de Marvao , Declan P. O'Regan , Daniel Rueckert , Jinming Duan

The establishment of image correspondence through robust image registration is critical to many clinical tasks such as image fusion, organ atlas creation, and tumor growth monitoring, and is a very challenging problem. Since the beginning…

Quantitative Methods · Quantitative Biology 2020-01-22 Grant Haskins , Uwe Kruger , Pingkun Yan

This article presents a general Bayesian learning framework for multi-modal groupwise image registration. The method builds on probabilistic modelling of the image generative process, where the underlying common anatomy and geometric…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Xinzhe Luo , Xin Wang , Linda Shapiro , Chun Yuan , Jianfeng Feng , Xiahai Zhuang

Deep learning based deformable registration methods have become popular in recent years. However, their ability to generalize beyond training data distribution can be poor, significantly hindering their usability. LUMIR brain registration…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Joel Honkamaa , Pekka Marttinen

Deformable registration continues to be one of the key challenges in medical image analysis. While iconic registration methods have started to benefit from the recent advances in medical deep learning, the same does not yet apply for the…

Computer Vision and Pattern Recognition · Computer Science 2019-09-18 Lasse Hansen , Doris Dittmer , Mattias P. Heinrich

Embedding of large but redundant data, such as images or text, in a hierarchy of lower-dimensional spaces is one of the key features of representation learning approaches, which nowadays provide state-of-the-art solutions to problems once…

Computer Vision and Pattern Recognition · Computer Science 2022-06-13 Gianluca Berardi , Luca De Luigi , Samuele Salti , Luigi Di Stefano

Recent deep learning-based methods have shown promising results and runtime advantages in deformable image registration. However, analyzing the effects of hyperparameters and searching for optimal regularization parameters prove to be too…

Computer Vision and Pattern Recognition · Computer Science 2021-07-06 Tony C. W. Mok , Albert C. S. Chung

Classical deformable registration techniques achieve impressive results and offer a rigorous theoretical treatment, but are computationally intensive since they solve an optimization problem for each image pair. Recently, learning-based…

Computer Vision and Pattern Recognition · Computer Science 2019-07-26 Adrian V. Dalca , Guha Balakrishnan , John Guttag , Mert R. Sabuncu