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Since simulating quantum computers requires exponentially more classical resources, efficient algorithms are extremely helpful. We analyze algorithms that create single qubit and specific controlled qubit matrix representations of gates.…

Quantum Physics · Physics 2007-05-23 Eric Hsu

The integration of quantum computers within classical High-Performance Computing (HPC) infrastructures is receiving increasing attention, with the former expected to serve as accelerators for specific computational tasks. However, combining…

The unit commitment (UC) problem stands as a critical optimization challenge in the electrical power industry. It is classified as NP-hard, placing it among the most intractable problems to solve. This paper introduces a novel hybrid…

Quantum Physics · Physics 2024-12-17 Bruna Salgado , André Sequeira , Luis Paulo Santos

Quantum computers can exploit a Hilbert space whose dimension increases exponentially with the number of qubits. In experiment, quantum supremacy has recently been achieved by the Google team by using a noisy intermediate-scale quantum…

Quantum Physics · Physics 2021-02-02 Suguru Endo , Zhenyu Cai , Simon C. Benjamin , Xiao Yuan

AlphaFold has achieved groundbreaking advancements in protein structure prediction, exerting profound influence across biology, medicine, and drug discovery. However, its reliance on multiple sequence alignment (MSA) is inherently…

Quantum Physics · Physics 2025-06-03 Rong Chen , Quan-Xin Mei , Wen-Ding Zhao , Lin Yao , Hao-Xiang Yang , Shun-Yao Zhang , Jiao Chen , Hong-Lin Li

We apply numerical optimization and linear algebra algorithms for classical computers to the problem of automatically synthesizing algorithms for quantum computers. Using our framework, we apply several common techniques from these…

Numerical Analysis · Mathematics 2025-09-16 Yuxin Huang , Benjamin E. Grossman-Ponemon , David A. B. Hyde

The problem of selecting an appropriate number of features in supervised learning problems is investigated in this paper. Starting with common methods in machine learning, we treat the feature selection task as a quadratic unconstrained…

Quantum Physics · Physics 2023-06-21 Gerhard Hellstern , Vanessa Dehn , Martin Zaefferer

Molecular docking, which aims to find the most stable interacting configuration of a set of molecules, is of critical importance to drug discovery. Although a considerable number of classical algorithms have been developed to carry out…

Biomolecules · Quantitative Biology 2022-10-21 Mohit Pandey , Tristan Zaborniak , Hans Melo , Alexey Galda , Vikram K. Mulligan

We address the problem of implementing bottleneck layers from classical pre-trained neural networks on a quantum computer, with the goal of exploring intrinsically quantum ansatz for representing large linear layers within hybrid…

Quantum Physics · Physics 2026-04-09 Borja Aizpurua , Sukhbinder Singh , Román Orús

Quantum annealing offers a promising paradigm for solving NP-hard combinatorial optimization problems, but its practical application is severely hindered by two challenges: the complex, manual process of translating problem descriptions…

Machine Learning · Computer Science 2025-09-03 Huixiang Zhang , Mahzabeen Emu , Salimur Choudhury

Quantum Annealing, or Quantum Stochastic Optimization, is a classical randomized algorithm which provides good heuristics for the solution of hard optimization problems. The algorithm, suggested by the behaviour of quantum systems, is an…

Quantum Physics · Physics 2011-07-06 Diego de Falco , Dario Tamascelli

Quantum computers can execute algorithms that dramatically outperform classical computation. As the best-known example, Shor discovered an efficient quantum algorithm for factoring integers, whereas factoring appears to be difficult for…

Quantum Physics · Physics 2010-01-19 Andrew M. Childs , Wim van Dam

Using Quantum Computers to solve problems in Recommender Systems that classical computers cannot address is a worthwhile research topic. In this paper, we use Quantum Annealers to address the feature selection problem in recommendation…

Information Retrieval · Computer Science 2024-07-04 Jiayang Niu , Jie Li , Ke Deng , Yongli Ren

Hybrid classical quantum optimization methods have become an important tool for efficiently solving problems in the current generation of NISQ computers. These methods use an optimization algorithm executed in a classical computer, fed with…

Quantum Physics · Physics 2023-08-02 J. Gidi , B. Candia , A. D. Muñoz-Moller , A. Rojas , L. Pereira , M. Muñoz , L. Zambrano , A. Delgado

Multi-Agent Path Finding (MAPF) focuses on determining conflict-free paths for multiple agents navigating through a shared space to reach specified goal locations. This problem becomes computationally challenging, particularly when handling…

Artificial Intelligence · Computer Science 2025-07-10 Thore Gerlach , Loong Kuan Lee , Frédéric Barbaresco , Nico Piatkowski

The optimization of front-end crude oil scheduling is a critical determinant of refinery profitability and operational stability. However, the coupling of discrete logistics events (e.g., vessel berthing) with continuous material flows…

Quantum Physics · Physics 2026-04-30 Jian Yang , Bohang Wang , Lina Wang , Jiacheng Chen , Gaoxiang Tang , Zihan Deng , Wending Zhao , Xianfeng Cai

The current state of quantum computing is commonly described as the Noisy Intermediate-Scale Quantum era. Available computers contain a few dozens of qubits and can perform a few dozens of operations before the inevitable noise erases all…

Quantum Physics · Physics 2024-09-25 Ijaz Ahamed Mohammad , Matej Pivoluska , Martin Plesch

Quantum computing offers an alternative paradigm for addressing combinatorial optimization problems compared to classical computing. Despite recent hardware improvements, the execution of empirical quantum optimization experiments at scales…

A range of quantum algorithms, especially those leveraging variational parameterization and circuit-based optimization, are being studied as alternatives for solving classically intractable combinatorial optimization problems (COPs).…

Quantum Physics · Physics 2025-06-18 Monit Sharma , Hoong Chuin Lau

Classical optimization algorithms in machine learning often take a long time to compute when applied to a multi-dimensional problem and require a huge amount of CPU and GPU resource. Quantum parallelism has a potential to speed up machine…

Quantum Physics · Physics 2019-11-21 Venkat R. Dasari , Mee Seong Im , Lubjana Beshaj