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Combinatorial threshold-linear networks (CTLNs) are a special class of inhibition-dominated TLNs defined from directed graphs. Like more general TLNs, they display a wide variety of nonlinear dynamics including multistability, limit cycles,…

Neurons and Cognition · Quantitative Biology 2022-08-16 Caitlyn Parmelee , Samantha Moore , Katherine Morrison , Carina Curto

Neural network models in neuroscience allow one to study how the connections between neurons shape the activity of neural circuits in the brain. In this chapter, we study Combinatorial Threshold-Linear Networks (CTLNs) in order to…

Neurons and Cognition · Quantitative Biology 2018-04-05 Katherine Morrison , Carina Curto

Neural circuits in the brain perform a variety of essential functions, including input classification, pattern completion, and the generation of rhythms and oscillations that support processes such as breathing and locomotion. There is also…

Neurons and Cognition · Quantitative Biology 2024-10-16 Juliana Londono Alvarez

Networks of interconnected neurons display diverse patterns of collective activity. Relating this collective activity to the network's connectivity structure is a key goal of computational neuroscience. We approach this question for…

Neurons and Cognition · Quantitative Biology 2025-06-09 Caitlin Lienkaemper , Gabriel Koch Ocker

Combinatorial threshold-linear networks (CTLNs) are a special class of recurrent neural networks whose dynamics are tightly controlled by an underlying directed graph. Recurrent networks have long been used as models for associative memory…

Neurons and Cognition · Quantitative Biology 2023-11-21 Carina Curto , Jesse Geneson , Katherine Morrison

Nonlinear network dynamics are notoriously difficult to understand. Here we study a class of recurrent neural networks called combinatorial threshold-linear networks (CTLNs) whose dynamics are determined by the structure of a directed…

Neurons and Cognition · Quantitative Biology 2021-09-16 Daniela Egas Santander , Stefania Ebli , Alice Patania , Nicole Sanderson , Felicia Burtscher , Katherine Morrison , Carina Curto

Threshold-linear networks consist of simple units interacting in the presence of a threshold nonlinearity. Competitive threshold-linear networks have long been known to exhibit multistability, where the activity of the network settles into…

Neurons and Cognition · Quantitative Biology 2023-10-17 Katherine Morrison , Anda Degeratu , Vladimir Itskov , Carina Curto

A broad range of nonlinear processes over networks are governed by threshold dynamics. So far, existing mathematical theory characterizing the behavior of such systems has largely been concerned with the case where the thresholds are…

Dynamical Systems · Mathematics 2013-05-21 Leon Chang , Jeffrey Cochran , Henning S. Mortveit , Siddharth Raval , Matthew Schroeder

The architecture of a neural network constrains the potential dynamics that can emerge. Some architectures may only allow for a single dynamic regime, while others display a great deal of flexibility with qualitatively different dynamics…

Combinatorics · Mathematics 2020-08-04 Carina Curto , Christopher Langdon , Katherine Morrison

Continuous attractor neural networks generate a set of smoothly connected attractor states. In memory systems of the brain, these attractor states may represent continuous pieces of information such as spatial locations and head directions…

Disordered Systems and Neural Networks · Physics 2019-01-16 Chi Chung Alan Fung , Tomoki Fukai

To any inhibition-dominated threshold-linear network (TLN) we can associate a directed graph that captures the pattern of strong and weak inhibition between neurons. Robust motifs are graphs for which the structure of fixed points in the…

Neurons and Cognition · Quantitative Biology 2019-12-18 Carina Curto , Christopher Langdon , Katherine Morrison

Threshold-linear networks (TLNs) are models of neural networks that consist of simple, perceptron-like neurons and exhibit nonlinear dynamics that are determined by the network's connectivity. The fixed points of a TLN, including both…

Neurons and Cognition · Quantitative Biology 2018-08-06 Carina Curto , Jesse Geneson , Katherine Morrison

Graphical domination was first introduced in [1] in the context of combinatorial threshold-linear networks (CTLNs). There it was shown that when a domination relationship exists between a pair of vertices in a graph, certain fixed points in…

Neurons and Cognition · Quantitative Biology 2025-10-07 Carina Curto

This is a brief overview of results from [arXiv:2107.10244, ref 11], on network architectures that produce sequential dynamics in a special family of inhibition-dominated neural networks. It was written for SIAM DSWeb.

Neurons and Cognition · Quantitative Biology 2022-12-19 Caitlyn Parmelee , Juliana Londono Alvarez , Carina Curto , Katherine Morrison

Sequential activation of neurons is a common feature of network activity during a variety of behaviors, including working memory and decision making. Previous network models for sequences and memory emphasized specialized architectures in…

Neurons and Cognition · Quantitative Biology 2016-03-16 Kanaka Rajan , Christopher D Harvey , David W Tank

Recordings of increasingly large neural populations have revealed that the firing of individual neurons is highly coordinated. When viewed in the space of all possible patterns, the collective activity forms non-linear structures called…

Neurons and Cognition · Quantitative Biology 2025-11-14 Arianna Di Bernardo , Adrian Valente , Francesca Mastrogiuseppe , Srdjan Ostojic

The relationship between the properties of a dynamical system and the structure of its defining equations has long been studied in many contexts. Here we study this problem for the class of conjunctive (resp. disjunctive) Boolean networks,…

Combinatorics · Mathematics 2008-05-13 Abdul Salam Jarrah , Reinhard Laubenbacher , Alan Veliz-Cuba

Threshold-linear networks are a common class of firing rate models that describe recurrent interactions among neurons. Unlike their linear counterparts, these networks generically possess multiple stable fixed points (steady states), making…

Neurons and Cognition · Quantitative Biology 2016-12-28 Carina Curto , Katherine Morrison

Recurrence networks are complex networks, constructed from time series data, having several practical applications. Though their properties when constructed with the threshold value \epsilon chosen at or just above the percolation threshold…

Chaotic Dynamics · Physics 2016-07-19 Rinku Jacob , K. P. Harikrishnan , R. Misra , G. Ambika

Despite their apparent simplicity, random Boolean networks display a rich variety of dynamical behaviors. Much work has been focused on the properties and abundance of attractors. We here derive an expression for the number of attractors in…

Molecular Networks · Quantitative Biology 2007-05-23 Björn Samuelsson , Carl Troein
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