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Positron emission tomography (PET) is widely used in various clinical applications, including cancer diagnosis, heart disease and neuro disorders. The use of radioactive tracer in PET imaging raises concerns due to the risk of radiation…

Computer Vision and Pattern Recognition · Computer Science 2017-12-13 Junshen Xu , Enhao Gong , John Pauly , Greg Zaharchuk

Positron Emission Tomography (PET) is a vital imaging modality widely used in clinical diagnosis and preclinical research but faces limitations in image resolution and signal-to-noise ratio due to inherent physical degradation factors.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-11 Boxiao Yu , Kuang Gong

Reducing scan times, radiation dose, and enhancing image quality for lower-performance scanners, are critical in low-dose PET imaging. Deep learning techniques have been investigated for PET image denoising. However, existing models have…

Positron emission tomography (PET) is a critical tool for diagnosing tumors and neurological disorders but poses radiation risks to patients, particularly to sensitive populations. While reducing injected radiation dose mitigates this risk,…

Image and Video Processing · Electrical Eng. & Systems 2026-04-01 Yucun Hou , Fenglin Zhan , Xin Cheng , Chenxi Li , Ziquan Yuan , Runze Liao , Haihao Wang , Jianlang Hua , Jing Wu , Jianyong Jiang

Positron Emission Tomography (PET) is a functional imaging modality that enables the visualization of biochemical and physiological processes across various tissues. Recently, deep learning (DL)-based methods have demonstrated significant…

Image and Video Processing · Electrical Eng. & Systems 2026-01-16 Yiran Sun , Osama Mawlawi

Most of the Deep Neural Networks (DNNs) based CT image denoising literature shows that DNNs outperform traditional iterative methods in terms of metrics such as the RMSE, the PSNR and the SSIM. In many instances, using the same metrics, the…

Computer Vision and Pattern Recognition · Computer Science 2021-11-19 Prabhat KC , Rongping Zeng , M. Mehdi Farhangi , Kyle J. Myers

As PET imaging is accompanied by substantial radiation exposure and cancer risk, reducing radiation dose in PET scans is an important topic. Recently, diffusion models have emerged as the new state-of-the-art generative model to generate…

Image and Video Processing · Electrical Eng. & Systems 2023-11-30 Huidong Xie , Weijie Gan , Bo Zhou , Xiongchao Chen , Qiong Liu , Xueqi Guo , Liang Guo , Hongyu An , Ulugbek S. Kamilov , Ge Wang , Chi Liu

Positron Emission Tomography (PET) is an important clinical imaging tool but inevitably introduces radiation hazards to patients and healthcare providers. Reducing the tracer injection dose and eliminating the CT acquisition for attenuation…

Computer Vision and Pattern Recognition · Computer Science 2024-06-18 Tianqi Chen , Jun Hou , Yinchi Zhou , Huidong Xie , Xiongchao Chen , Qiong Liu , Xueqi Guo , Menghua Xia , James S. Duncan , Chi Liu , Bo Zhou

As PET imaging is accompanied by substantial radiation exposure and cancer risk, reducing radiation dose in PET scans is an important topic. However, low-count PET scans often suffer from high image noise, which can negatively impact image…

Image and Video Processing · Electrical Eng. & Systems 2023-05-01 Huidong Xie , Qiong Liu , Bo Zhou , Xiongchao Chen , Xueqi Guo , Chi Liu

Positron emission tomography (PET) is an important functional medical imaging technique often used in the evaluation of certain brain disorders, whose reconstruction problem is ill-posed. The vast majority of reconstruction methods in PET…

Image and Video Processing · Electrical Eng. & Systems 2023-06-09 Tin Vlašić , Tomislav Matulić , Damir Seršić

Low-dose positron emission tomography (PET) image reconstruction methods have potential to significantly improve PET as an imaging modality. Deep learning provides a promising means of incorporating prior information into the image…

Computer Vision and Pattern Recognition · Computer Science 2024-09-11 Cameron Dennis Pain , Yasmeen George , Alex Fornito , Gary Egan , Zhaolin Chen

To obtain high-quality positron emission tomography (PET) while minimizing radiation exposure, a range of methods have been designed to reconstruct standard-dose PET (SPET) from corresponding low-dose PET (LPET) images. However, most…

Image and Video Processing · Electrical Eng. & Systems 2024-04-11 Yuchen Fei , Yanmei Luo , Yan Wang , Jiaqi Cui , Yuanyuan Xu , Jiliu Zhou , Dinggang Shen

Low-dose Positron Emission Tomography (PET) reduces radiation exposure but suffers from severe noise and quantitative degradation. Diffusion-based denoising models achieve strong final reconstructions, yet their reverse trajectories are…

Positron emission tomography (PET) is the most sensitive molecular imaging modality routinely applied in our modern healthcare. High radioactivity caused by the injected tracer dose is a major concern in PET imaging and limits its clinical…

Image and Video Processing · Electrical Eng. & Systems 2023-04-04 Yuxin Xue , Yige Peng , Lei Bi , Dagan Feng , Jinman Kim

Positron emission tomography (PET) is an advanced medical imaging technique that plays a crucial role in non-invasive clinical diagnosis. However, while reducing radiation exposure through low-dose PET scans is beneficial for patient…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Bin Huang , Xubiao Liu , Lei Fang , Qiegen Liu , Bingxuan Li

Deep neural networks have received considerable attention in clinical imaging, particularly with respect to the reduction of radiation risk. Lowering the radiation dose by reducing the photon flux inevitably results in the degradation of…

Image and Video Processing · Electrical Eng. & Systems 2021-09-14 Khalid L. Alsamadony , Ertugrul U. Yildirim , Guenther Glatz , Umair bin Waheed , Sherif M. Hanafy

Positron Emission Tomography (PET) is an essential technique in many clinical applications that allows for quantitative imaging at the molecular level. This study aims to develop a denoising method using novel dilated convolutional neural…

Medical Physics · Physics 2021-01-27 Karl Spuhler , Mario Serrano-Sosa , Renee Cattell , Christine DeLorenzo , Chuan Huang

Positron emission tomography (PET) scans expose patients to radiation, which can be mitigated by reducing the dose, albeit at the cost of diminished quality. This makes low-dose (LD) PET recovery an active research area. Previous studies…

Image and Video Processing · Electrical Eng. & Systems 2026-03-11 Ghulam Nabi Ahmad Hassan Yar , Himashi Peiris , Victoria Mar , Cameron Dennis Pain , Zhaolin Chen

Dynamic positron emission tomography (PET) images can reveal the distribution of tracers in the organism and the dynamic processes involved in biochemical reactions, and it is widely used in clinical practice. Despite the high effectiveness…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Jie Sun , Junyan Zhang , Qian Xia , Chuanfu Sun , Yumei Chen , Yunjie Yang , Huafeng Liu , Wentao Zhu , Qiegen Liu

Low-dose Positron Emission Tomography (PET) imaging presents a significant challenge due to increased noise and reduced image quality, which can compromise its diagnostic accuracy and clinical utility. Denoising diffusion probabilistic…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Boxiao Yu , Savas Ozdemir , Jiong Wu , Yizhou Chen , Ruogu Fang , Kuangyu Shi , Kuang Gong
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