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Related papers: Pooled testing to isolate infected individuals

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We propose `Tapestry', a novel approach to pooled testing with application to COVID-19 testing with quantitative Reverse Transcription Polymerase Chain Reaction (RT-PCR) that can result in shorter testing time and conservation of reagents…

Pooled testing is widely used for screening for viral or bacterial infections with low prevalence when individual testing is not cost-efficient. Pooled testing with qualitative assays that give binary results has been well-studied. However,…

Methodology · Statistics 2020-11-03 Tao Liu , Joseph W Hogan , Wanning Su , Yizhen Xu , Michael J Daniels , Kantor Rami

Group testing can save testing resources in the context of the ongoing COVID-19 pandemic. In group testing, we are given $n$ samples, one per individual, and arrange them into $m < n$ pooled samples, where each pool is obtained by mixing a…

Applications · Statistics 2023-11-03 Ritesh Goenka , Shu-Jie Cao , Chau-Wai Wong , Ajit Rajwade , Dror Baron

In group testing, the task is to determine the distinguished members of a set of objects L by asking subset queries of the form ``does the subset Q of L contain a distinguished object?'' The primary biological application of group testing…

Combinatorics · Mathematics 2008-02-03 Emanuel Knill , S. Muthukrishnan

The outbreak of the global COVID-19 pandemic results in unprecedented demand for fast and efficient testing of large numbers of patients for the presence of SARS-CoV-2 coronavirus. Beside technical improvements of the cost and speed of…

Methodology · Statistics 2020-12-16 Andrzej Jaszkiewicz

There are multiple testing methods to ascertain an infection in an individual and they vary in their performances, cost and delay. Unfortunately, better performing tests are sometimes costlier and time consuming and can only be done for a…

Social and Information Networks · Computer Science 2021-06-17 Harish Sasikumar , Manoj Varma

Group testing is one of the fundamental problems in coding theory and combinatorics in which one is to identify a subset of contaminated items from a given ground set. There has been renewed interest in group testing recently due to its…

Information Theory · Computer Science 2022-02-11 Mira Gonen , Michael Langberg , Alex Sprintson

Polymerase chain reaction (PCR) testing is the gold standard for diagnosing COVID-19. PCR amplifies the virus DNA 40 times to produce measurements of viral loads that span seven orders of magnitude. Unfortunately, the outputs of these tests…

Quantitative Methods · Quantitative Biology 2022-01-19 Hsin-Po Wang , Ryan Gabrys , Alexander Vardy

The group testing problem is concerned with identifying a small number $k \sim n^\theta$ for $\theta \in (0,1)$ of infected individuals in a large population of size $n$. At our disposal is a testing procedure that allows us to test groups…

Discrete Mathematics · Computer Science 2019-11-19 Max Hahn-Klimroth , Philipp Loick

The COVID-19 crisis highlighted the importance of non-medical interventions, such as testing and isolation of infected individuals, in the control of epidemics. Here, we show how to minimize testing needs while maintaining the number of…

Systems and Control · Electrical Eng. & Systems 2024-07-04 D. Acemoglu , A. Fallah , A. Giometto , D. Huttenlocher , A. Ozdaglar , F. Parise , S. Pattathil

We argue that frequent sampling of the fraction of infected people (either by random testing or by analysis of sewage water), is central to managing the COVID-19 pandemic because it both measures in real time the key variable controlled by…

Populations and Evolution · Quantitative Biology 2020-07-24 Markus Müller , Peter M. Derlet , Christopher Mudry , Gabriel Aeppli

This paper is based on the observation that, during Covid-19 epidemic, the choice of which individuals should be tested has an important impact on the effectiveness of selective confinement measures. This decision problem is closely related…

Physics and Society · Physics 2020-12-24 Matthias Pezzutto , Nicolas Bono Rossello , Luca Schenato , Emanuele Garone

Group testing enables to identify infected individuals in a population using a smaller number of tests than individual testing. To achieve this, group testing algorithms commonly assume knowledge of the number of infected individuals;…

Information Theory · Computer Science 2023-05-16 Chaorui Yao , Pavlos Nikolopoulos , Christina Fragouli

Group testing has recently attracted significant attention from the research community due to its applications in diagnostic virology. An instance of the group testing problem includes a ground set of individuals which includes a small…

Information Theory · Computer Science 2022-02-25 Esmaeil Karimi , Anoosheh Heidarzadeh , Krishna R. Narayanan , Alex Sprintson

Since the beginning of 2020, the coronavirus disease 2019 (COVID-19) has spread rapidly in the city of Wuhan, P.R. China, and subsequently, across the world. The swift spread of the virus is largely attributed to its stealth transmissions…

Applications · Statistics 2020-04-06 Grace Yi , Wenqing He , Dennis Kon-Jin Lin , Chun-Ming Yu

The use of group testing to locate all instances of disease in a large population of blood samples was first considered seventy years ago. Since then, several methods have been used to approximate the minimum expected number of tests. The…

Applications · Statistics 2015-03-24 Seth Zimmerman

The COVID-19 is sweeping the world with deadly consequences. Its contagious nature and clinical similarity to other pneumonias make separating subjects contracted with COVID-19 and non-COVID-19 viral pneumonia a priority and a challenge.…

Machine Learning · Computer Science 2020-05-15 Forrest Sheng Bao , Youbiao He , Jie Liu , Yuanfang Chen , Qian Li , Christina R. Zhang , Lei Han , Baoli Zhu , Yaorong Ge , Shi Chen , Ming Xu , Liu Ouyang

Accurate detection of infected individuals is one of the critical steps in stopping any pandemic. When the underlying infection rate of the disease is low, testing people in groups, instead of testing each individual in the population, can…

In this work, we consider the sparsity-constrained community-based group testing problem, where the population follows a community structure. In particular, the community consists of $F$ families, each with $M$ members. A number $k_f$ out…

Information Theory · Computer Science 2024-03-20 Sarthak Jain , Martina Cardone , Soheil Mohajer

The experience of Singapur and South Korea makes it clear that under certain circumstances massive testing is an effective way for containing the advance of the COVID-19. In this paper, we propose a modified SEIR model which takes into…

Applications · Statistics 2020-12-24 José Luis Sainz-Pardo , José Valero