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In computational science and in computer science, research software is a central asset for research. Computational science is the application of computer science and software engineering principles to solving scientific problems, whereas…

Software Engineering · Computer Science 2019-08-19 Wilhelm Hasselbring , Leslie Carr , Simon Hettrick , Heather Packer , Thanassis Tiropanis

The reproduction and replication of research results has become a major issue for a number of scientific disciplines. In computer science and related computational disciplines such as systems biology, the challenges closely revolve around…

Software Engineering · Computer Science 2017-07-31 Tom Crick , Benjamin A. Hall , Samin Ishtiaq

Developing generalizable AI for medical imaging requires both access to large, multi-center datasets and standardized, reproducible tooling within research environments. However, leveraging real-world imaging data in clinical research…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Ünal Akünal , Markus Bujotzek , Stefan Denner , Benjamin Hamm , Klaus Kades , Philipp Schader , Jonas Scherer , Marco Nolden , Peter Neher , Ralf Floca , Klaus Maier-Hein

We present work flows and a software module for machine learning model building in surface science and heterogeneous catalysis. This includes fingerprinting atomic structures from 3D structure and/or connectivity information, it includes…

As the amount of scientific data continues to grow at ever faster rates, the research community is increasingly in need of flexible computational infrastructure that can support the entirety of the data science lifecycle, including…

Computers and Society · Computer Science 2016-04-12 Robert L. Grossman , Allison Heath , Mark Murphy , Maria Patterson , Walt Wells

By combining metal nodes with organic linkers we can potentially synthesize millions of possible metal organic frameworks (MOFs). At present, we have libraries of over ten thousand synthesized materials and millions of in-silico predicted…

Materials Science · Physics 2020-06-12 Kevin Maik Jablonka , Daniele Ongari , Seyed Mohamad Moosavi , Berend Smit

Sustainable software ecosystems are difficult to build, and require concerted effort, community norms and collaborations. In science it is especially important to establish communities in which faculty, staff, students and open-source…

Software Engineering · Computer Science 2013-09-13 Marcus D. Hanwell , Amitha Perera , Wes Turner , Patrick O'Leary , Katie Osterdahl , Bill Hoffman , Will Schroeder

Applied machine learning (ML) has rapidly spread throughout the physical sciences; in fact, ML-based data analysis and experimental decision-making has become commonplace. We suggest a shift in the conversation from proving that ML can be…

Materials Science · Physics 2021-12-21 Naohiro Fujinuma , Brian L. DeCost , Jason Hattrick-Simpers , Samuel E. Lofland

The integration of artificial intelligence (AI) into science education is transforming the design and function of learning materials, offering new affordances for personalization, authenticity, and accessibility. This chapter examines how…

Computers and Society · Computer Science 2026-02-25 Xiaoming Zhai , Kent Crippen

Over the past year, there has been a robust debate about the benefits and risks of open sourcing foundation models. However, this discussion has often taken place at a high level of generality or with a narrow focus on specific technical…

Modern large-scale scientific discovery requires multidisciplinary collaboration across diverse computing facilities, including High Performance Computing (HPC) machines and the Edge-to-Cloud continuum. Integrated data analysis plays a…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-08-21 Renan Souza , Tyler J. Skluzacek , Sean R. Wilkinson , Maxim Ziatdinov , Rafael Ferreira da Silva

Simulation tools are playing an increasingly important role in materials science and engineering and beyond their well established importance in research and development, these tools have a significant pedagogical potential. We describe a…

Many sciences have made significant breakthroughs by adopting online tools that help organize, structure and mine information that is too detailed to be printed in journals. In this paper, we introduce OpenML, a place for machine learning…

Machine Learning · Computer Science 2014-08-04 Joaquin Vanschoren , Jan N. van Rijn , Bernd Bischl , Luis Torgo

While the requirements of enterprise and web applications have driven the development of Cloud computing, some of its key features, such as customized environments and rapid elasticity, could also benefit scientific applications. However,…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-06-23 Álvaro López García , Enol Fernández del Castillo

MaRDI Open Interfaces is a software project aimed at improving reuse and interoperability in Scientific Computing by alleviating the difficulties of crossing boundaries between different programming languages, in which numerical packages…

Mathematical Software · Computer Science 2025-11-18 Dmitry I. Kabanov , Stephan Rave , Mario Ohlberger

Scientific workflows are powerful tools for management of scalable experiments, often composed of complex tasks running on distributed resources. Existing cyberinfrastructure provides components that can be utilized within repeatable…

Computers and Society · Computer Science 2019-03-05 Ilkay Altintas , Shweta Purawat , Daniel Crawl , Alok Singh , Kyle Marcus

We are in the era of the Big Data. In Astronomy and Astrophysics, the massive amounts of data generated are, as of today, in the Peta-scale if not already in the Exa-scale. In the near future, we will see the data collected size and…

Instrumentation and Methods for Astrophysics · Physics 2023-02-23 S. Bertocco

Cloud computing provides a great opportunity for scientists, as it enables large-scale experiments that cannot are too long to run on local desktop machines. Cloud-based computations can be highly parallel, long running and data-intensive,…

Software Engineering · Computer Science 2016-12-07 Maria Spichkova , Heinz W. Schmidt , Ian E. Thomas , Iman I. Yusuf , Steve Androulakis , Grischa R. Meyer

With advanced imaging, sequencing, and profiling technologies, multiple omics data become increasingly available and hold promises for many healthcare applications such as cancer diagnosis and treatment. Multimodal learning for integrative…

Genomics · Quantitative Biology 2022-12-20 Sina Tabakhi , Mohammod Naimul Islam Suvon , Pegah Ahadian , Haiping Lu
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