English
Related papers

Related papers: Analysis of training and seed bias in small molecu…

200 papers

Deep generative models have demonstrated successful applications in learning non-linear data distributions through a number of latent variables and these models use a nonlinear function (generator) to map latent samples into the data space.…

Computer Vision and Pattern Recognition · Computer Science 2023-04-04 Pourya Shamsolmoali , Masoumeh Zareapoor , Huiyu Zhou , Dacheng Tao , Xuelong Li

Variational autoencoders (VAE) are directed generative models that learn factorial latent variables. As noted by Burda et al. (2015), these models exhibit the problem of factor over-pruning where a significant number of stochastic factors…

Machine Learning · Computer Science 2017-08-08 Serena Yeung , Anitha Kannan , Yann Dauphin , Li Fei-Fei

Data preprocessing is a critical part of time series data analysis. Data from connected medical devices often have missing or abnormal values during acquisition. Handling such situations requires additional assumptions and domain knowledge.…

Signal Processing · Electrical Eng. & Systems 2025-12-16 Ali AbuSaleh , Mehdi Rahim

In principle, applying variational autoencoders (VAEs) to sequential data offers a method for controlled sequence generation, manipulation, and structured representation learning. However, training sequence VAEs is challenging:…

Machine Learning · Computer Science 2022-12-19 Đorđe Miladinović , Kumar Shridhar , Kushal Jain , Max B. Paulus , Joachim M. Buhmann , Mrinmaya Sachan , Carl Allen

For planning of power systems and for the calibration of operational tools, it is essential to analyse system performance in a large range of representative scenarios. When the available historical data is limited, generative models are a…

Systems and Control · Electrical Eng. & Systems 2022-12-16 Chenguang Wang , Ensieh Sharifnia , Zhi Gao , Simon H. Tindemans , Peter Palensky

Any autoencoder network can be turned into a generative model by imposing an arbitrary prior distribution on its hidden code vector. Variational Autoencoder (VAE) [2] uses a KL divergence penalty to impose the prior, whereas Adversarial…

Machine Learning · Computer Science 2018-07-23 Mahdi Azarafrooz

Trajectory generation and prediction are two interwoven tasks that play important roles in planner evaluation and decision making for intelligent vehicles. Most existing methods focus on one of the two and are optimized to directly output…

Robotics · Computer Science 2022-11-02 Ruochen Jiao , Xiangguo Liu , Bowen Zheng , Dave Liang , Qi Zhu

Previous work explored blending levels from existing games to create levels for a new game that mixes properties of the original games. In this paper, we use Variational Autoencoders (VAEs) for improving upon such techniques. VAEs are…

Machine Learning · Computer Science 2020-02-28 Anurag Sarkar , Zhihan Yang , Seth Cooper

Deep generative models are reported to be useful in broad applications including image generation. Repeated inference between data space and latent space in these models can denoise cluttered images and improve the quality of inferred…

Machine Learning · Statistics 2017-12-13 Yoshihiro Nagano , Ryo Karakida , Masato Okada

Generating novel drug molecules with desired biological properties is a time consuming and complex task. Conditional generative adversarial models have recently been proposed as promising approaches for de novo drug design. In this paper,…

Quantitative Methods · Quantitative Biology 2021-10-26 Yuansan Liu , James Bailey

Neural networks are used for channel decoding, channel detection, channel evaluation, and resource management in multi-input and multi-output (MIMO) wireless communication systems. In this paper, we consider the problem of finding precoding…

Signal Processing · Electrical Eng. & Systems 2022-05-06 Evgeny Bobrov , Alexander Markov , Sviatoslav Panchenko , Dmitry Vetrov

Generating novel molecules with optimal properties is a crucial step in many industries such as drug discovery. Recently, deep generative models have shown a promising way of performing de-novo molecular design. Although graph generative…

Machine Learning · Computer Science 2018-11-27 Rim Assouel , Mohamed Ahmed , Marwin H Segler , Amir Saffari , Yoshua Bengio

Clinical trials face mounting challenges: fragmented patient populations, slow enrollment, and unsustainable costs, particularly for late phase trials in oncology and rare diseases. While external control arms built from real-world data…

Machine Learning · Computer Science 2025-11-21 Perrine Chassat , Van Tuan Nguyen , Lucas Ducrot , Emilie Lanoy , Agathe Guilloux

We introduce a Deep Kernel Learning Variational Autoencoder (VAE-DKL) framework that integrates the generative power of a Variational Autoencoder (VAE) with the predictive nature of Deep Kernel Learning (DKL). The VAE learns a latent…

Machine Learning · Computer Science 2025-03-06 Boris N. Slautin , Utkarsh Pratiush , Doru C. Lupascu , Maxim A. Ziatdinov , Sergei V. Kalinin

Variational autoencoders (VAEs) employ Bayesian inference to interpret sensory inputs, mirroring processes that occur in primate vision across both ventral (Higgins et al., 2021) and dorsal (Vafaii et al., 2023) pathways. Despite their…

Machine Learning · Computer Science 2024-12-10 Hadi Vafaii , Dekel Galor , Jacob L. Yates

Often the analysis of time-dependent chemical and biophysical systems produces high-dimensional time-series data for which it can be difficult to interpret which individual features are most salient. While recent work from our group and…

This paper presents a generative approach to speech enhancement based on a recurrent variational autoencoder (RVAE). The deep generative speech model is trained using clean speech signals only, and it is combined with a nonnegative matrix…

Machine Learning · Computer Science 2020-02-11 Simon Leglaive , Xavier Alameda-Pineda , Laurent Girin , Radu Horaud

The variational autoencoder (VAE) is a simple and efficient generative artificial intelligence method for modeling complex probability distributions of various types of data, such as images and texts. However, it suffers some main…

Machine Learning · Computer Science 2025-02-14 Xi Chen , Shaofan Li

Colorization is an ambiguous problem, with multiple viable colorizations for a single grey-level image. However, previous methods only produce the single most probable colorization. Our goal is to model the diversity intrinsic to the…

Computer Vision and Pattern Recognition · Computer Science 2017-04-28 Aditya Deshpande , Jiajun Lu , Mao-Chuang Yeh , Min Jin Chong , David Forsyth

Domain adaptation and covariate shift are big issues in deep learning and they ultimately affect any causal inference algorithms that rely on deep neural networks. Causal effect variational autoencoder (CEVAE) is trained to predict the…

Machine Learning · Computer Science 2022-09-22 Daniel Jiwoong Im , Kyunghyun Cho , Narges Razavian