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The large-scale multiple testing inherent to high throughput biological data necessitates very high statistical stringency and thus true effects in data are difficult to detect unless they have high effect sizes. One solution to this…

Methodology · Statistics 2017-12-21 Mohamad S. Hasan

Research on the localization of the genetic basis associated with diseases or traits has been widely conducted in the last a few decades. Scan methods have been developed for region-based analysis in whole-genome association studies,…

Methodology · Statistics 2024-10-31 Wei Zhang , Fan Wang , Fang Yao

This paper offers a commentary on the use of notions of statistical significance in choice modelling. We review the reasons for uncertainty in parameter estimates, provide a precise discussion on the computation of measures of uncertainty…

Econometrics · Economics 2026-05-18 Stephane Hess , Andrew Daly , Michiel Bliemer , Angelo Guevara , Ricardo Daziano , Thijs Dekker

Selectivity estimation aims at estimating the number of database objects that satisfy a selection criterion. Answering this problem accurately and efficiently is essential to many applications, such as density estimation, outlier detection,…

Databases · Computer Science 2021-05-28 Yaoshu Wang , Chuan Xiao , Jianbin Qin , Rui Mao , Onizuka Makoto , Wei Wang , Rui Zhang , Yoshiharu Ishikawa

In this paper we present a fast scalable heuristic for bin packing that partitions the given problem into identical sub-problems of constant size and solves these constant size sub-problems by considering only a constant number of bin…

Data Structures and Algorithms · Computer Science 2019-04-30 Srikrishnan Divakaran

We analyze safety problems of complex systems using the methods of mathematical statistics for testing the output variables of a code simulating the operation of the system under consideration when the input variables are uncertain. We have…

Data Analysis, Statistics and Probability · Physics 2007-05-23 L. Pal , M. Makai

The purpose of this project was to collect and analyse data about the comparability and real-life applicability of published results focusing on Microsoft Windows malware, more specifically the impact of dataset size and testing dataset…

Cryptography and Security · Computer Science 2022-06-14 David Illes

Win statistics, including the win ratio, net benefit, and win odds, summarize treatment effects on hierarchical composite endpoints by sequentially comparing patient pairs on component outcomes ordered by clinical importance, proceeding to…

Methodology · Statistics 2026-05-27 Xi Fang , Fan Li

The brain processes visual inputs having structure over a large range of spatial scales. The precise mechanisms or algorithms used by the brain to achieve this feat are largely unknown and an open problem in visual neuroscience. In…

Neurons and Cognition · Quantitative Biology 2018-07-04 Keith Hayton , Dimitrios Moirogiannis , Marcelo Magnasco

High-dimensional changepoint inference, adaptable to diverse alternative scenarios, has attracted significant attention in recent years. In this paper, we propose an adaptive and robust approach to changepoint testing. Specifically, by…

Methodology · Statistics 2025-04-29 Jixuan Liu , Long Feng , Liuhua Peng , Zhaojun Wang

Critical states are sometimes identified experimentally through power-law statistics or universal scaling functions. We show here that such features naturally emerge from networks in self-sustained irregular regimes away from criticality.…

Neurons and Cognition · Quantitative Biology 2017-02-08 Jonathan Touboul , Alain Destexhe

According to the concept of typicality, an ensemble average can be accurately approximated by an expectation value with respect to a single pure state drawn at random from a high-dimensional Hilbert space. This random-vector approximation,…

Statistical Mechanics · Physics 2020-05-22 J. Schnack , J. Richter , T. Heitmann , J. Richter , R. Steinigeweg

Hyperdimensional computing (HDC) is a method to perform classification that uses binary vectors with high dimensions and the majority rule. This approach has the potential to be energy-efficient and hence deemed suitable for…

Machine Learning · Computer Science 2023-10-13 Zhanglu Yan , Shida Wang , Kaiwen Tang , Weng-Fai Wong

Over the past decades, statisticians and machine-learning researchers have developed literally thousands of new tools for the reduction of high-dimensional data in order to identify the variables most responsible for a particular trait.…

Machine Learning · Statistics 2012-05-31 Chamont Wang , Jana Gevertz , Chaur-Chin Chen , Leonardo Auslender

We review the methodology for measurements of two point functions of the cosmological observables, both power spectra and correlation functions. For pseudo-$C_\ell$ estimators, we will argue that the window weighted overdensity field can…

Cosmology and Nongalactic Astrophysics · Physics 2021-08-27 Sukhdeep Singh

We study the maximum score statistic to detect and estimate local signals in the form of change-points in the level, slope, or other property of a sequence of observations, and to segment the sequence when there appear to be multiple…

Statistics Theory · Mathematics 2021-11-03 Xiao Fang , David Siegmund

Estimating a fractal dimension from a finite stochastic trajectory is a finite-size scaling problem: the apparent box-counting exponent is shaped by an occupancy crossover between the resolved range of scales and the finite number of…

Statistical Mechanics · Physics 2026-05-28 Bon A. Koo , Edward Ju

This work is motivated by learning the individualized minimal clinically important difference, a vital concept to assess clinical importance in various biomedical studies. We formulate the scientific question into a high-dimensional…

Methodology · Statistics 2023-03-28 Huijie Feng , Jingyi Duan , Yang Ning , Jiwei Zhao

Linear regression models depend directly on the design matrix and its properties. Techniques that efficiently estimate model coefficients by partitioning rows of the design matrix are increasingly popular for large-scale problems because…

Machine Learning · Statistics 2019-07-23 Michael J. Kane , Bryan Lewis , Sekhar Tatikonda , Simon Urbanek

The scaling of correlations as a function of system size provides important hints to understand critical phenomena on a variety of systems. Its study in biological systems offers two challenges: usually they are not of infinite size, and in…

Disordered Systems and Neural Networks · Physics 2020-07-17 Daniel A. Martin , Tiago L. Ribeiro , Sergio A. Cannas , Tomas S. Grigera , Dietmar Plenz , Dante R. Chialvo