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Phylogenetic networks provide a way to describe and visualize evolutionary histories that have undergone so-called reticulate evolutionary events such as recombination, hybridization or horizontal gene transfer. The level k of a network…

Populations and Evolution · Quantitative Biology 2008-07-21 Leo van Iersel , Steven Kelk , Matthias Mnich

Polyploidization is an evolutionary process by which a species acquires multiple copies of its complete set of chromosomes. The reticulate nature of the signal left behind by it means that phylogenetic networks offer themselves as a…

Populations and Evolution · Quantitative Biology 2023-02-21 Katharina T. Huber , Liam J. Maher

Many classes of phylogenetic networks have been proposed in the literature. A feature of several of these classes is that if one restricts a network in the class to a subset of its leaves, then the resulting network may no longer lie within…

Populations and Evolution · Quantitative Biology 2025-09-24 Michael Fuchs , Mike Steel

We provide precise asymptotic estimates for the number of general phylogenetic networks by using analytic combinatorial methods. Recently, this approach is studied by Fuchs, Gittenberger, and the author himself (Australasian Journal of…

Combinatorics · Mathematics 2020-06-01 Marefatollah Mansouri

The network of networks(NON) research is focused on studying the properties of n interdependent networks which is ubiquitous in the real world. Identifying the influential nodes in the network of networks is theoretical and practical…

Social and Information Networks · Computer Science 2015-01-26 Meizhu Li , Qi Zhang , Qi Liu , Yong Deng

Tree containment problem is a fundamental problem in phylogenetic study, as it is used to verify a network model. It asks whether a given network contain a subtree that resembles a binary tree. The problem is NP-complete in general, even in…

Populations and Evolution · Quantitative Biology 2017-02-15 Andreas Gunawan

In computational phylogenetics, the problem of constructing a supertree of a given set of rooted input trees can be formalized in different ways, to cope with contradictory information in the input. We consider the Minimum Flip Supertree…

Data Structures and Algorithms · Computer Science 2011-04-25 Sebastian Böcker

Pruning the parameters of deep neural networks has generated intense interest due to potential savings in time, memory and energy both during training and at test time. Recent works have identified, through an expensive sequence of training…

Machine Learning · Computer Science 2020-11-20 Hidenori Tanaka , Daniel Kunin , Daniel L. K. Yamins , Surya Ganguli

With the success of deep learning, recent efforts have been focused on analyzing how learned networks make their classifications. We are interested in analyzing the network output based on the network structure and information flow through…

Machine Learning · Computer Science 2018-02-13 Sandeep Konam , Ian Quah , Stephanie Rosenthal , Manuela Veloso

In phylogenetic networks, it is desirable to estimate edge lengths in substitutions per site or calendar time. Yet, there is a lack of scalable methods that provide such estimates. Here we consider the problem of obtaining edge length…

Populations and Evolution · Quantitative Biology 2024-08-06 Jingcheng Xu , Cécile Ané

Phylogenetic (evolutionary) trees and networks are leaf-labeled graphs that are widely used to represent the evolutionary relationships between entities such as species, languages, cancer cells, and viruses. To reconstruct and analyze…

Data Structures and Algorithms · Computer Science 2023-08-21 Michael J. Dinneen , Pankaj S. Ghodla , Simone Linz

We study the enumeration of spinal tree-child phylogenetic networks, a rigid family of tree-child networks in which all internal vertices lie on a single root--to--leaf path. We provide two complementary combinatorial frameworks. First, we…

Combinatorics · Mathematics 2026-05-12 Pau Vives , Anna de Mier , Gabriel Cardona , Joan Carles Pons

In this paper, we lay the groundwork on the comparison of phylogenetic networks based on edge contractions and expansions as edit operations, as originally proposed by Robinson and Foulds to compare trees. We prove that these operations…

Data Structures and Algorithms · Computer Science 2025-02-21 Bertrand Marchand , Nadia Tahiri , Olivier Tremblay-Savard , Manuel Lafond

Phylogenetic networks and, more generally, directed acyclic graphs (DAGs) represent hierarchical structure beyond trees, for instance in the presence of reticulate evolutionary events such as hybridization or horizontal gene transfer. A…

Populations and Evolution · Quantitative Biology 2026-05-22 Marc Hellmuth , Anna Lindeberg , Vincent Moulton

A spanning tree of a network or graph is a subgraph that connects all nodes with the least number or weight of edges. The spanning tree is one of the most straightforward techniques for network simplification and sampling, and for…

Social and Information Networks · Computer Science 2025-12-03 Lovro Šubelj

A cycle basis in an undirected graph is a minimal set of simple cycles whose symmetric differences include all Eulerian subgraphs of the given graph. We define a rooted cycle basis to be a cycle basis in which all cycles contain a specified…

Data Structures and Algorithms · Computer Science 2015-04-21 David Eppstein , J. Michael McCarthy , Brian E. Parrish

We show a first-order asymptotics result for the number of galled networks with $n$ leaves. This is the first class of phylogenetic networks of {\it large} size for which an asymptotic counting result of such strength can be obtained. In…

Combinatorics · Mathematics 2021-10-06 Michael Fuchs , Guan-Ru Yu , Louxin Zhang

Deep Learning plays a significant role in assisting humans in many aspects of their lives. As these networks tend to get deeper over time, they extract more features to increase accuracy at the cost of additional inference latency. This…

Machine Learning · Computer Science 2021-08-12 Mehrshad Zandigohar , Deniz Erdogmus , Gunar Schirner

A fundamental algorithmic problem in computational biology is to find all subgraphs of a given type (superbubbles, snarls, and ultrabubbles) in a directed or bidirected input graph. These correspond to regions of genetic variation and are…

The structure of an evolving network contains information about its past. Extracting this information efficiently, however, is, in general, a difficult challenge. We formulate a fast and efficient method to estimate the most likely history…

Physics and Society · Physics 2020-09-16 Gábor Timár , Rui A. da Costa , Sergey N. Dorogovtsev , José F. F. Mendes