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In many chemical and biological applications, systems of differential equations containing unknown parameters are used to explain empirical observations and experimental data. The DEs are typically nonlinear and difficult to analyze,…
The complexity and size of state-of-the-art cell models have significantly increased in part due to the requirement that these models possess complex cellular functions which are thought--but not necessarily proven--to be important. Modern…
Critical phenomena of quantum systems are useful for enhancement of quantum sensing. However, experimental realizations of criticality enhancement have been confined to very few systems, owing to the stringent requirements, including the…
Photonic sensors have many applications in a range of physical settings, from measuring mechanical pressure in manufacturing to detecting protein concentration in biomedical samples. A variety of sensing approaches exist, and plasmonic…
Detecting specific target analytes and differentiating them from interfering background effects is a crucial but challenging task in complex multi-component solutions commonly encountered in environmental, chemical, biological, and medical…
Optical molecular sensing techniques are often limited by the refractive index change associated with the probed interactions. In this work, we present a closed form analytical model to estimate the magnitude of optical refractive index…
Quantum sensing encompasses highly promising techniques with diverse applications including noise-reduced imaging, super-resolution microscopy as well as imaging and spectroscopy in challenging spectral ranges. These detection schemes use…
Biosensors based on the principle of surface plasmon resonance (SPR) detection were used to measure biomolecular interactions in sarcomeres and changes of the dielectric constant of tubulin samples with varying concentration. At SPR,…
Our understanding of the physics of biological molecules, such as proteins and DNA, is limited because the approximations we usually apply to model inert materials are not in general applicable to soft, chemically inhomogeneous systems. The…
Quantum resources can enhance the sensitivity of a device beyond the classical shot noise limit and, as a result, revolutionize the field of metrology through the development of quantum-enhanced sensors. In particular, plasmonic sensors,…
Quantum sensing with solid-state systems finds broad applications in diverse areas ranging from material and biomedical sciences to fundamental physics. Several solid-state spin sensors have been developed, facilitating the ultra-sensitive…
Enzymes are essential to maintain organisms alive. Some of the reactions they catalyze are associated with a change in reagents chirality, hence their activity can be tracked by using optical means. However, illumination affects enzyme…
Quantum physics holds the promise of enabling certain tasks with better performance than possible when only classical resources are employed. The quantum phenomena present in many experiments signify nonclassical behavior, but do not always…
The applications of spin-based quantum sensors to measurements probing fundamental physics are surveyed. Experimental methods and technologies developed for quantum information science have rapidly advanced in recent years, and these tools…
This paper presents a novel methodology for modeling memristive biosensing within COMSOL Multiphysics, focusing on critical performance metrics such as antigen-antibody binding concentration and output resistive states. By studying the…
By exploiting the exotic quantum states of a probe, it is possible to realize efficient sensors that are attractive for practical metrology applications and fundamental studies. Similar to other quantum technologies, quantum sensing is…
We investigate the sensitivity with which the temperature and the chemical potential characterizing quantum gases can be measured. We calculate the corresponding quantum Fisher information matrices for both fermionic and bosonic gases. For…
Using quantum systems as sensors or probes has been shown to greatly improve the precision of parameter estimation by exploiting unique quantum features such as entanglement. A major task in quantum sensing is to design the optimal…
This thesis presents three studies in quantum-enhanced sensing and target detection. The first study explores covert target detection using optical or microwave probes, establishing quantum-mechanical limits on the error probabilities of…
We present a comprehensive study of the interaction of human serum albumin (HSA) with poly(acrylic acid) (PAA; number average degree of polymerization: 25) in aqueous solution. The interaction of HSA with PAA is studied in dilute solution…