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Knowledge of what spatial elements of medical images deep learning methods use as evidence is important for model interpretability, trustiness, and validation. There is a lack of such techniques for models in regression tasks. We propose a…

Image and Video Processing · Electrical Eng. & Systems 2020-07-27 Ricardo Bigolin Lanfredi , Joyce D. Schroeder , Clement Vachet , Tolga Tasdizen

Image translation based on a generative adversarial network (GAN-IT) is a promising method for the precise localization of abnormal regions in chest X-ray images (AL-CXR) even without the pixel-level annotation. However, heterogeneous…

Image and Video Processing · Electrical Eng. & Systems 2024-06-18 Kyungsu Kim , Seong Je Oh , Chae Yeon Lim , Ju Hwan Lee , Tae Uk Kim , Myung Jin Chung

In the last few years, deep learning classifiers have shown promising results in image-based medical diagnosis. However, interpreting the outputs of these models remains a challenge. In cancer diagnosis, interpretability can be achieved by…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Kangning Liu , Yiqiu Shen , Nan Wu , Jakub Chłędowski , Carlos Fernandez-Granda , Krzysztof J. Geras

Robust segmentation for non-elongated tissues in medical images is hard to realize due to the large variation of the shape, size, and appearance of these tissues in different patients. In this paper, we present an end-to-end trainable deep…

Image and Video Processing · Electrical Eng. & Systems 2020-04-06 Qian Yu , Yinghuan Shi , Yefeng Zheng , Yang Gao , Jianbing Zhu , Yakang Dai

-Background. Network neuroscience examines the brain as a complex system represented by a network (or connectome), providing deeper insights into the brain morphology and function, allowing the identification of atypical brain connectivity…

Neurons and Cognition · Quantitative Biology 2020-09-01 Mert Lostar , Islem Rekik

Given image labels as the only supervisory signal, we focus on harvesting, or mining, thoracic disease localizations from chest X-ray images. Harvesting such localizations from existing datasets allows for the creation of improved data…

Computer Vision and Pattern Recognition · Computer Science 2018-07-04 Jinzheng Cai , Le Lu , Adam P. Harrison , Xiaoshuang Shi , Pingjun Chen , Lin Yang

We consider the problem of abnormality localization for clinical applications. While deep learning has driven much recent progress in medical imaging, many clinical challenges are not fully addressed, limiting its broader usage. While…

Computer Vision and Pattern Recognition · Computer Science 2021-12-24 Xi Ouyang , Srikrishna Karanam , Ziyan Wu , Terrence Chen , Jiayu Huo , Xiang Sean Zhou , Qian Wang , Jie-Zhi Cheng

Graph neural networks (GNNs) have been proposed for medical image segmentation, by predicting anatomical structures represented by graphs of vertices and edges. One such type of graph is predefined with fixed size and connectivity to…

Image and Video Processing · Electrical Eng. & Systems 2023-03-20 Qian Li , Yunguan Fu , Qianye Yang , Zhijiang Du , Hongjian Yu , Yipeng Hu

In recent years, deep learning based methods have shown success in essential medical image analysis tasks such as segmentation. Post-processing and refining the results of segmentation is a common practice to decrease the misclassifications…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Ufuk Demir , Atahan Ozer , Yusuf H. Sahin , Gozde Unal

Chest radiographs are primarily employed for the screening of cardio, thoracic and pulmonary conditions. Machine learning based automated solutions are being developed to reduce the burden of routine screening on Radiologists, allowing them…

Computer Vision and Pattern Recognition · Computer Science 2020-04-27 Arunava Chakravarty , Tandra Sarkar , Nirmalya Ghosh , Ramanathan Sethuraman , Debdoot Sheet

Supervised learning method requires a large volume of annotated datasets. Collecting such datasets is time-consuming and expensive. Until now, very few annotated COVID-19 imaging datasets are available. Although self-supervised learning…

Image and Video Processing · Electrical Eng. & Systems 2020-12-14 Li Sun , Ke Yu , Kayhan Batmanghelich

Inferencing Gene Regulatory Networks (GRNs) from gene expression data is a pivotal challenge in systems biology, and several innovative computational methods have been introduced. However, most of these studies have not considered the…

Quantitative Methods · Quantitative Biology 2025-01-10 Jiaqi Xiong , Nan Yin , Shiyang Liang , Haoyang Li , Yingxu Wang , Duo Ai , Fang Pan , Jingjie Wang

The inference of gene regulatory networks (GRNs) is a foundational stride towards deciphering the fundamentals of complex biological systems. Inferring a possible regulatory link between two genes can be formulated as a link prediction…

Machine Learning · Computer Science 2025-04-25 Binon Teji , Swarup Roy

Deep learning models have demonstrated remarkable results for various computer vision tasks, including the realm of medical imaging. However, their application in the medical domain is limited due to the requirement for large amounts of…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Aryan Singh , Pepijn Van de Ven , Ciarán Eising , Patrick Denny

The lack of fine-grained annotations hinders the deployment of automated diagnosis systems, which require human-interpretable justification for their decision process. In this paper, we address the problem of weakly supervised…

Computer Vision and Pattern Recognition · Computer Science 2022-10-10 Constantin Seibold , Jens Kleesiek , Heinz-Peter Schlemmer , Rainer Stiefelhagen

Accurate feature matching and correspondence in endoscopic images play a crucial role in various clinical applications, including patient follow-up and rapid anomaly localization through panoramic image generation. However, developing…

Computer Vision and Pattern Recognition · Computer Science 2023-06-21 Manel Farhat , Achraf Ben-Hamadou

Identifying and locating diseases in chest X-rays are very challenging, due to the low visual contrast between normal and abnormal regions, and distortions caused by other overlapping tissues. An interesting phenomenon is that there exist…

Image and Video Processing · Electrical Eng. & Systems 2020-11-22 Gangming Zhao , Chaowei Fang , Guanbin Li , Licheng Jiao , Yizhou Yu

In spite of the compelling achievements that deep neural networks (DNNs) have made in medical image computing, these deep models often suffer from degraded performance when being applied to new test datasets with domain shift. In this…

Computer Vision and Pattern Recognition · Computer Science 2018-06-06 Cheng Chen , Qi Dou , Hao Chen , Pheng-Ann Heng

Graph neural networks (GNNs) have been widely investigated in the field of semi-supervised graph machine learning. Most methods fail to exploit adequate graph information when labeled data is limited, leading to the problem of…

Machine Learning · Computer Science 2023-03-15 Linxuan Song , Wenxuan Tu , Sihang Zhou , Xinwang Liu , En Zhu

Medical image interpretation using deep learning has shown promise but often requires extensive expert-annotated datasets. To reduce this annotation burden, we develop an Image-Graph Contrastive Learning framework that pairs chest X-rays…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 Sameer Khanna , Daniel Michael , Marinka Zitnik , Pranav Rajpurkar