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We study an optimal control problem where the objective is to find the best vaccine allocation during an epidemic outbreak. The epidemic dynamics is described by an age-structured SIR model with nonlocal interactions. Both the infection and…

Optimization and Control · Mathematics 2026-05-19 Luís Almeida , Romain Ducasse , Elisa Paparelli

The dynamics of fractional population sizes y_i=Y_i/N in homogeneous compartment models with time dependent total population N is analyzed. Assuming constant per capita birth and death rates the vector field Y_i'=V_i(Y) naturally projects…

Populations and Evolution · Quantitative Biology 2023-04-17 Florian Nill

Knowing which individuals can be more efficient in spreading a pathogen throughout a determinate environment is a fundamental question in disease control. Indeed, over the last years the spread of epidemic diseases and its relationship with…

A stochastic epidemic model accounting for the effect of contact-tracing on the spread of an infectious disease is studied. Precisely, individuals identified as infected may contribute to detecting other infectious individuals by providing…

Probability · Mathematics 2009-03-28 Stéphan Clémençon , Viet Chi Tran , Hector De Arazoza

We propose a network behavioral-feedback Susceptible-Infected-Recovered (SIR) epidemic model in which the interaction matrix describing the infection rates across subpopulations depends in feedback on the current epidemic state. This model…

Dynamical Systems · Mathematics 2025-07-08 Martina Alutto , Leonardo Cianfanelli , Giacomo Como , Fabio Fagnani

Up to now, the effects of having heterogeneous networks of contacts have been studied mostly for diseases which are not persistent in time, i.e., for diseases where the infectious period can be considered very small compared to the lifetime…

Physics and Society · Physics 2015-05-18 J. Sanz , L. M. Floria , Y. Moreno

We simulate a spatial behavioral model of the diffusion of an infection to understand the role of geographic characteristics: the number and distribution of outbreaks, population size, density, and agents' movements. We show that several…

General Economics · Economics 2022-01-31 Alberto Bisin , Andrea Moro

We develop a new perturbation method for studying quasi-neutral competition in a broad class of stochastic competition models, and apply it to the analysis of fixation of competing strains in two epidemic models. The first model is a…

Statistical Mechanics · Physics 2016-10-06 Oleg Kogan , Michael Khasin , Baruch Meerson , David Schneider , Christopher R. Myers

Motile organisms can form stable agglomerates such as cities or colonies. In the outbreak of a highly contagious disease, the control of large-scale epidemic spread depends on factors like the number and size of agglomerates, travel rate…

Populations and Evolution · Quantitative Biology 2023-04-03 Pablo de Castro , Felipe Urbina , Ariel Norambuena , Francisca Guzmán-Lastra

We numerically study the dynamics of the SIR disease model on small-world networks by using a large-deviation approach. This allows us to obtain the probability density function of the total fraction of infected nodes and of the maximum…

Physics and Society · Physics 2022-09-01 Yannick Feld , Alexander K. Hartmann

This paper is concerned with two frequency-dependent SIS epidemic reaction-diffusion models in heterogeneous environment, with a cross-diffusion term modeling the effect that susceptible individuals tend to move away from higher…

Analysis of PDEs · Mathematics 2018-07-20 Huicong Li , Rui Peng , Tian Xiang

When the body gets infected by a pathogen the immune system develops pathogen-specific immunity. Induced immunity decays in time and years after recovery the host might become susceptible again. Exposure to the pathogen in the environment…

Dynamical Systems · Mathematics 2014-11-13 Maria Vittoria Barbarossa , Gergely Röst

A class of models of biological population and communities with a singular equilibrium at the origin is analyzed; it is shown that these models can possess a dynamical regime of deterministic extinction, which is crucially important from…

Quantitative Methods · Quantitative Biology 2007-05-23 Faina S Berezovskaya , Artem S Novozhilov , Georgy P Karev

We propose a dynamical model for describing the spread of epidemics. This model is an extension of the SIQR (susceptible-infected-quarantined-recovered) and SIRP (susceptible-infected-recovered-pathogen) models used earlier to describe…

Physics and Society · Physics 2022-12-08 S. P. Lukyanets , I. S. Gandzha , O. V. Kliushnichenko

We consider an SIR epidemic model propagating on a configuration model network, where the degree distribution of the vertices is given and where the edges are randomly matched. The evolution of the epidemic is summed up into three…

Probability · Mathematics 2012-05-09 Laurent Decreusefond , Jean-Stéphane Dhersin , Pascal Moyal , Viet Chi Tran

Infectious diseases outbreaks are often characterized by a spatial component induced by hosts' distribution, mobility, and interactions. Spatial models that incorporate hosts' movements are being used to describe these processes, to…

Physics and Society · Physics 2012-07-20 Chiara Poletto , Michele Tizzoni , Vittoria Colizza

Susceptible-Infected-Recovered (SIR) models have been used for decades to understand epidemic outbreak dynamics. We develop an SIR model specifically designed to study the effects of population behavior with respect to health and…

Populations and Evolution · Quantitative Biology 2023-08-03 Jasmin Nunuvero , Angelique Santiago , Moshe Cohen , Anca Radulescu

Infectious diseases spread through human networks. Susceptible-Infected-Removed (SIR) model is one of the epidemic models to describe infection dynamics on a complex network connecting individuals. In the metapopulation SIR model, each node…

Physics and Society · Physics 2015-08-27 Kanako Mizuno , Kazue Kudo

We study the spread of susceptible-infected-recovered (SIR) infectious diseases where an individual's infectiousness and probability of recovery depend on his/her "age" of infection. We focus first on early outbreak stages when stochastic…

Populations and Evolution · Quantitative Biology 2009-05-14 Joel Miller , Bahman Davoudi , Rafael Meza , Anja Slim , Babak Pourbohloul

In most models of the spread of disease over contact networks it is assumed that the probabilities per unit time of disease transmission and recovery from disease are constant, implying exponential distributions of the time intervals for…

Physics and Society · Physics 2010-07-23 Brian Karrer , M. E. J. Newman
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