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In this paper, we introduce a three-dimensional mathematical model of collagen contraction with microbuckling based on the two-dimensional model previously developed by the authors. The model both qualitatively and quantitatively replicates…

Cell Behavior · Quantitative Biology 2018-01-03 Emily Jennings Evans , John C. Dallon

We present an \textit{ab initio} method of diffusion, relaxation and dephasing processes of arbitrary observables, and corresponding diffusion lengths and lifetimes in solids. The method is based on linearized density-matrix master…

Computational Physics · Physics 2025-09-29 Junqing Xu

Signaling molecules play an important role for many cellular functions. We investigate here a general system of two membrane reaction-diffusion equations coupled to a diffusion equation inside the cell by a Robin-type boundary condition and…

Analysis of PDEs · Mathematics 2015-06-16 Andreas Rätz , Matthias Röger

The cell cortex, a thin film of active material assembled below the cell membrane, plays a key role in cellular symmetry breaking processes such as cell polarity establishment and cell division. Here, we present a minimal model of the…

Biological Physics · Physics 2019-09-30 Alexander Mietke , V. Jemseena , K. Vijay Kumar , Ivo F. Sbalzarini , Frank Jülicher

The dispersal of cells from an initially constrained location is a crucial aspect of many physiological phenomena ranging from morphogenesis to tumour spreading. In such processes, the way cell-cell interactions impact the motion of single…

We study the effect of a one-dimensional driving field on the interface between two coexisting phases in a two dimensional model. This is done by considering an Ising model on a cylinder with Glauber dynamics in all sites and additional…

Statistical Mechanics · Physics 2015-11-06 Or Cohen , David Mukamel

With the aim to characterize the formation and propagation of bulges in cylindrical rubber balloons, we carry out an expansion of the non-linear axisymmetric membrane model assuming slow axial variations. We obtain a diffuse interface model…

Classical Physics · Physics 2018-11-14 Claire Lestringant , Basile Audoly

This contribution belongs to a combinatorial approach to hyperbolic geometry and it is aimed at possible applications to computer simulations. It is based on the splitting method which was introduced by the author and which is reminded in…

Computational Geometry · Computer Science 2011-11-09 Maurice Margenstern

The spatio-temporal organization of proteins and the associated morphological changes in membranes are of importance in cell signaling. Several mechanisms that promote the aggregation of proteins at low cell surface concentrations have been…

Biological Physics · Physics 2018-04-18 K. K. Sreeja , P. B. Sunil Kumar

Cell cortex contraction is essential for shaping cells, enabling movement, ensuring proper division, maintaining tissue integrity, guiding development, and responding to mechanical signals - all critical for the life and health of…

Biological Physics · Physics 2024-09-05 Emanuel F. Teixeira , Carine P. Beatrici , Heitor C. M. Fernandes , Leonardo G. Brunnet

Recent work on particle-based models of tissues has suggested that any finite rate of cell division and cell death is sufficient to fluidize an epithelial tissue. At the same time, experimental evidence has indicated the existence of glassy…

Soft Condensed Matter · Physics 2019-05-07 Michael Czajkowski , Daniel M. Sussman , M. Cristina Marchetti , M. Lisa Manning

Here we describe an "information based exchange" model of brain function that ascribes to neocortex, basal ganglia, and thalamus distinct network functions. The model allows us to analyze whole brain system set point measures, such as the…

Neurons and Cognition · Quantitative Biology 2015-09-17 James Kozloski

The actin cytoskeleton in living cells has many types of crosslinkers. The mechanical interplay between these different crosslinker types is an open issue in cytoskeletal mechanics. We develop a framework to study the cooperativity and…

Soft Condensed Matter · Physics 2015-05-28 Moumita Das , D. A. Quint , J. M. Schwarz

We investigate two-phase flow in porous media and derive a two-scale model, which incorporates pore-scale phase distribution and surface tension into the effective behavior at the larger Darcy scale. The free-boundary problem at the pore…

Analysis of PDEs · Mathematics 2023-07-03 Mathis Kelm , Carina Bringedal , Bernd Flemisch

We study phases and transitions of the square-lattice double dimer model, consisting of two coupled replicas of the classical dimer model. As on the cubic lattice, we find a thermal phase transition from the Coulomb phase, a disordered but…

Statistical Mechanics · Physics 2020-11-23 Neil Wilkins , Stephen Powell

Computer simulations of the phenomenon of contact melting in binary alloys with chemical miscibility gap are performed on the basis of the phase field theory. Kinetics of the process is examined within the isothermal approximation, as a…

Materials Science · Physics 2014-01-09 V. Kartuzov , O. Bystrenko

In this article, the time-discretization of the fluid structure interaction model in the three-dimensional boundary domain is taken into account, which explains the mechanical interaction between the blood flow and the Hookean elasticity.…

Numerical Analysis · Mathematics 2025-02-19 Woojeong Kim

We have constructed a model for the kinetics of rupture of membranes under tension, applying physical principles relevant to lipid bilayers held together by hydrophobic interactions. The membrane is characterized by the bulk compressibility…

Biological Physics · Physics 2009-11-07 Luc Fournier , Bela Joos

In this work, we first propose a diffuse interface model for simulating N phase flows with solid liquid phase change. In this model, a phase field approach is adopted to capture multiphase fluid interfaces, and an enthalpy based formulation…

Fluid Dynamics · Physics 2026-03-25 Jiangxu Huang , Chengjie Zhan , Zhenhua Chai , Changsheng Huang , Xi Liu

Interactions between crawling cells, which are essential for many biological processes, can be quantified by measuring cell-cell collisions. Conventionally, experiments of cell-cell collisions are conducted on two-dimensional flat…

Biological Physics · Physics 2025-10-24 Yongtian Luo , Amrinder S. Nain , Brian A. Camley