English
Related papers

Related papers: Stochastic model of T Cell repolarization during t…

200 papers

We propose an alternative mechanism for intracellular cargo transport which results from motor induced longitudinal fluctuations of cytoskeletal microtubules (MT). The longitudinal fluctuations combined with transient cargo binding to the…

Soft Condensed Matter · Physics 2007-05-23 Igor M. Kulić , Philip C. Nelson

We study a lattice gas model of hard-core particles on a square lattice experiencing nearest neighbour attraction $J$. Each particle has an internal orientation, independent of the others, that point towards one of the four nearest…

Statistical Mechanics · Physics 2024-09-20 Chandraniva Guha Ray , Indranil Mukherjee , P. K. Mohanty

Inelastic Electron Tuneling Spectroscopy (IETS) is a powerful spectroscopy that allows one to investigate the nature of local excitations and energy transfer in the system of interest. We study IETS for Topological Insulators (TI) and…

Mesoscale and Nanoscale Physics · Physics 2013-01-11 Jian-Huang She , Jonas Fransson , A. R. Bishop , Alexander V. Balatsky

The plant microtubule cortical array is a striking feature of all growing plant cells. It consists of a more or less homogeneously distributed array of highly aligned microtubules connected to the inner side of the plasma membrane and…

Soft Condensed Matter · Physics 2013-05-29 Rhoda J. Hawkins , Simon H. Tindemans , Bela M. Mulder

Substrate-based cell motility is essential for fundamental biological processes, such as tissue growth, wound healing and immune response. Even if a comprehensive understanding of this motility mode remains elusive, progress has been…

Cell Behavior · Quantitative Biology 2016-05-23 Wieland Marth , Axel Voigt

The cytoskeleton in eukaryotic cells plays several crucial roles. In terms of intracellular transport, motor proteins use the cytoskeletal filaments as a backbone along which they can actively transport biological cargos such as vesicles…

Biological Physics · Physics 2020-06-20 Adélaïde Raguin , Norbert Kern , Andrea Parmeggiani

We study the stationary properties of the Ising model that, while evolving towards its equilibrium state at temperature $T$ according to the Glauber dynamics, is stochastically reset to its fixed initial configuration with magnetisation…

Statistical Mechanics · Physics 2020-08-12 Matteo Magoni , Satya N. Majumdar , Gregory Schehr

Cells control the size and organization of biomolecular condensates formed by liquid-liquid phase separation (LLPS), but multiple mechanisms likely contribute to this control and remain to be fully elucidated. Here we propose a…

Biological Physics · Physics 2026-04-10 Le Qiao , Peter Gispert , Lukas S. Stelzl , Friederike Schmid

Chemotaxis is typically modeled in the context of cellular motion towards a static, exogenous source of chemoattractant. Here, we propose a time-dependent mechanism of chemotaxis in which a self-propelled particle ({\it e.g.}, a cell)…

Cell Behavior · Quantitative Biology 2026-05-12 Sarah A. Nowak , Buddhapriya Chakrabarti , Tom Chou , Ajay Gopinathan

The influence of random fluctuations on the recruitment of effector cells towards a tumor is studied by means of a stochastic mathematical model. Aggressively growing tumors are confronted against varying intensities of the cell-mediated…

Other Quantitative Biology · Quantitative Biology 2020-10-28 Irina Bashkirtseva , Lev Ryashko , Álvaro G. López , Jesus M. Seoane , Miguel A. F. Sanjuán

We study a system of $N$ noninteracting particles on a line in the presence of a harmonic trap $U(x)=\mu \bigl[x-z(t)\bigr]^2/2$, where the trap center $z(t)$ undergoes a bounded stochastic modulation. We show that this stochastic…

Statistical Mechanics · Physics 2024-10-21 Sanjib Sabhapandit , Satya N. Majumdar

We present a neuronal network model inspired by the Ising model, where each neuron is a binary spin ($s_i = \pm1$) interacting with its neighbors on a 2D lattice. Updates are asynchronous and follow Metropolis dynamics, with a…

Neurons and Cognition · Quantitative Biology 2025-06-10 Sajedeh Sarmastani , Maliheh Ghodrat , Yousef Jamali

By modifying and calibrating an active vertex model to experiments, we have simulated numerically a confluent cellular monolayer spreading on an empty space and the collision of two monolayers of different cells in an antagonistic migration…

Soft Condensed Matter · Physics 2021-04-02 L. L. Bonilla , A. Carpio , C. Trenado

We introduce a stochastic lattice gas model including two particle species and two parallel lanes. One lane with exclusion interaction and directed motion and the other lane without exclusion and unbiased diffusion, mimicking a micotubule…

Statistical Mechanics · Physics 2009-11-13 M. Ebbinghaus , L. Santen

Motile eukaryotic cells display distinct modes of migration that often occur within the same cell type. It remains unclear, however, whether transitions between the migratory modes require changes in external conditions, or whether the…

Pattern Formation and Solitons · Physics 2025-05-29 Jack M. Hughes , Cristina Martinez-Torres , Carsten Beta , Leah Edelstein-Keshet , Arik Yochelis

Cells perform directed motion in response to external stimuli that they detect by sensing the environment with their membrane protrusions. In particular, several biochemical and biophysical cues give rise to tactic migration in the…

Cell Behavior · Quantitative Biology 2020-07-15 N. Loy , M. Conte

The immunological synapse is a patterned collection of different types of receptors and ligands that forms in the intercellular junction between T Cells and antigen presenting cells (APCs) during recognition. The synapse is implicated in…

Soft Condensed Matter · Physics 2009-11-10 Subhadip Raychaudhuri , Arup K. Chakraborty , Mehran Kardar

Inside cells, various cargos are transported by teams of molecular motors. Intriguingly, the motors involved generally have opposite pulling directions, and the resulting cargo dynamics is a biased stochastic motion. It is an open question…

Biological Physics · Physics 2017-09-20 Sarah Klein , Cécile Appert-Rolland , Ludger Santen

We study a stochastic model for tumor cell growth with both multiplicative and additive colored noise as well as a non-zero cross-correlations in between. Whereas the death rate within the logistic model is altered by a deterministic term…

Cell Behavior · Quantitative Biology 2015-05-13 Thomas Bose , Steffen Trimper

We analyse a generic motility model, with the motility mechanism arising by contractile stress due to the interaction of myosin and actin. A hydrodynamic active polar gel theory is used to model the cytoplasm of a cell and is combined with…

Cell Behavior · Quantitative Biology 2015-07-06 Wieland Marth , Simon Praetorius , Axel Voigt