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The de novo design of molecular structures using deep learning generative models introduces an encouraging solution to drug discovery in the face of the continuously increased cost of new drug development. From the generation of original…

Biomolecules · Quantitative Biology 2021-02-08 Yuemin Bian , Xiang-Qun Xie

Sequential dependencies present a fundamental bottleneck in deploying large-scale autoregressive models, particularly for real-time applications. While traditional optimization approaches like pruning and quantization often compromise model…

Computation and Language · Computer Science 2025-10-09 Yunhai Hu , Zining Liu , Zhenyuan Dong , Tianfan Peng , Bradley McDanel , Sai Qian Zhang

Despite the tremendous progress in the estimation of generative models, the development of tools for diagnosing their failures and assessing their performance has advanced at a much slower pace. Recent developments have investigated metrics…

Machine Learning · Computer Science 2020-06-09 Josip Djolonga , Mario Lucic , Marco Cuturi , Olivier Bachem , Olivier Bousquet , Sylvain Gelly

Instance segmentation is data-hungry, and as model capacity increases, data scale becomes crucial for improving the accuracy. Most instance segmentation datasets today require costly manual annotation, limiting their data scale. Models…

Computer Vision and Pattern Recognition · Computer Science 2024-05-17 Chengxiang Fan , Muzhi Zhu , Hao Chen , Yang Liu , Weijia Wu , Huaqi Zhang , Chunhua Shen

Multimodal learning is a framework for building models that make predictions based on different types of modalities. Important challenges in multimodal learning are the inference of shared representations from arbitrary modalities and…

Machine Learning · Computer Science 2022-07-06 Masahiro Suzuki , Yutaka Matsuo

Deep generative models have garnered significant attention in low-level vision tasks due to their generative capabilities. Among them, diffusion model-based solutions, characterized by a forward diffusion process and a reverse denoising…

Computer Vision and Pattern Recognition · Computer Science 2025-02-26 Chunming He , Yuqi Shen , Chengyu Fang , Fengyang Xiao , Longxiang Tang , Yulun Zhang , Wangmeng Zuo , Zhenhua Guo , Xiu Li

Deep generative models provide powerful tools for distributions over complicated manifolds, such as those of natural images. But many of these methods, including generative adversarial networks (GANs), can be difficult to train, in part…

Machine Learning · Statistics 2017-11-08 Akash Srivastava , Lazar Valkov , Chris Russell , Michael U. Gutmann , Charles Sutton

Creative sketch is a universal way of visual expression, but translating images from an abstract sketch is very challenging. Traditionally, creating a deep learning model for sketch-to-image synthesis needs to overcome the distorted input…

Computer Vision and Pattern Recognition · Computer Science 2023-05-31 Qiang Wang , Di Kong , Fengyin Lin , Yonggang Qi

Generative artificial intelligence (AI) refers to algorithms that create synthetic but realistic output. Diffusion models currently offer state of the art performance in generative AI for images. They also form a key component in more…

Machine Learning · Computer Science 2023-12-27 Catherine F. Higham , Desmond J. Higham , Peter Grindrod

Artificial intelligence (AI) technology enables a range of enhancements in computer-aided instruction, from accelerating the creation of teaching materials to customizing learning paths based on learner outcomes. However, ensuring the…

Computers and Society · Computer Science 2025-11-19 Christina Perdikoulias , Chad Vance , Stephen M. Watt

Generative networks implicitly approximate complex densities from their sampling with impressive accuracy. However, because of the enormous scale of modern datasets, this training process is often computationally expensive. We cast…

Machine Learning · Computer Science 2020-03-03 Vincent Schellekens , Laurent Jacques

Generative adversarial network (GAN) has been shown to be useful in various applications, such as image recognition, text processing and scientific computing, due its strong ability to learn complex data distributions. In this study, a…

Geophysics · Physics 2021-09-14 Tianhao He , Dongxiao Zhang

Deep generative models (DGMs) are effective on learning multilayered representations of complex data and performing inference of input data by exploring the generative ability. However, little work has been done on examining or empowering…

Machine Learning · Computer Science 2015-12-16 Chongxuan Li , Jun Zhu , Tianlin Shi , Bo Zhang

Current developments in computer vision and deep learning allow to automatically generate hyper-realistic images, hardly distinguishable from real ones. In particular, human face generation achieved a stunning level of realism, opening new…

Computer Vision and Pattern Recognition · Computer Science 2019-10-08 Francesco Marra , Cristiano Saltori , Giulia Boato , Luisa Verdoliva

Deep generative models of 3D shapes have received a great deal of research interest. Yet, almost all of them generate discrete shape representations, such as voxels, point clouds, and polygon meshes. We present the first 3D generative model…

Computer Vision and Pattern Recognition · Computer Science 2021-08-17 Rundi Wu , Chang Xiao , Changxi Zheng

We consider multi-solution optimization and generative models for the generation of diverse artifacts and the discovery of novel solutions. In cases where the domain's factors of variation are unknown or too complex to encode manually,…

Machine Learning · Computer Science 2021-05-11 Alexander Hagg , Sebastian Berns , Alexander Asteroth , Simon Colton , Thomas Bäck

Explaining deep learning model inferences is a promising venue for scientific understanding, improving safety, uncovering hidden biases, evaluating fairness, and beyond, as argued by many scholars. One of the principal benefits of…

Machine Learning · Computer Science 2022-03-16 Asma Ghandeharioun , Been Kim , Chun-Liang Li , Brendan Jou , Brian Eoff , Rosalind W. Picard

Deep generative models provide a systematic way to learn nonlinear data distributions, through a set of latent variables and a nonlinear "generator" function that maps latent points into the input space. The nonlinearity of the generator…

Machine Learning · Statistics 2021-12-14 Georgios Arvanitidis , Lars Kai Hansen , Søren Hauberg

Deep generative models have demonstrated impressive performance in various computer vision applications, including image synthesis, video generation, and medical analysis. Despite their significant advancements, these models may be used for…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Jingyi Deng , Chenhao Lin , Zhengyu Zhao , Shuai Liu , Zhe Peng , Qian Wang , Chao Shen

Deep generative models can emulate the perceptual properties of complex image datasets, providing a latent representation of the data. However, manipulating such representation to perform meaningful and controllable transformations in the…

Machine Learning · Computer Science 2019-12-13 Michel Besserve , Arash Mehrjou , Rémy Sun , Bernhard Schölkopf
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