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A mechanism for self-organization of the degree of connectivity in model neural networks is studied. Network connectivity is regulated locally on the basis of an order parameter of the global dynamics which is estimated from an observable…

Statistical Mechanics · Physics 2009-11-07 Stefan Bornholdt , Torsten Roehl

Networks have been used to model many real-world phenomena to better understand the phenomena and to guide experiments in order to predict their behavior. Since incorrect models lead to incorrect predictions, it is vital to have a correct…

Molecular Networks · Quantitative Biology 2007-05-23 Natasa Przulj , Derek G. Corneil , Igor Jurisica

A determinant property of the structure of a biological network is the distribution of local connectivity patterns, i.e., network motifs. In this work, a method for creating directed, unweighted networks while promoting a certain…

Social and Information Networks · Computer Science 2016-07-29 Tuomo Mäki-Marttunen

Whereas the relationship between criticality of gene regulatory networks (GRNs) and dynamics of GRNs at a single cell level has been vigorously studied, the relationship between the criticality of GRNs and system properties at a higher…

Molecular Networks · Quantitative Biology 2018-01-29 Hyobin Kim , Hiroki Sayama

Multiplex networks are convenient mathematical representations for many real-world -- biological, social, and technological -- systems of interacting elements, where pairwise interactions among elements have different flavors. Previous…

Physics and Society · Physics 2020-05-26 Saeed Osat , Filippo Radicchi , Fragkiskos Papadopoulos

Successive whole genome duplications have recently been firmly established in all major eukaryote kingdoms. It is not clear, however, how such dramatic evolutionary process has contributed to shape the large scale topology of…

Molecular Networks · Quantitative Biology 2007-05-23 K. Evlampiev , H. Isambert

Biological networks provide insight into the complex organization of biological processes in a cell at the system level. They are an effective tool for understanding the comprehensive map of functional interactions, finding the functional…

Molecular Networks · Quantitative Biology 2017-09-14 Somaye Hashemifar

Identity, response to external stimuli, and spatial architecture of a living system are central topics of molecular biology. Presently, they are largely seen as a result of the interplay between a gene repertoire and the regulatory…

Molecular Networks · Quantitative Biology 2007-05-23 M. Cosentino Lagomarsino , P. Jona , B. Bassetti

Network control theory can be used to model how one should steer the brain between different states by driving a specific region with an input. The needed energy to control a network is often used to quantify its controllability, and…

Computational Engineering, Finance, and Science · Computer Science 2023-08-03 Seyed Samie Alizadeh Darbandi , Alex Fornito , Abdorasoul Ghasemi

How does connectivity impact network dynamics? We address this question by linking network characteristics on two scales. On the global scale we consider the coherence of overall network dynamics. We show that such \emph{global coherence}…

Neurons and Cognition · Quantitative Biology 2013-12-13 Yu Hu , James Trousdale , Krešimir Josić , Eric Shea-Brown

Pinning control on complex dynamical networks has emerged as a very important topic in recent trends of control theory due to the extensive study of collective coupled behaviors and their role in physics, engineering and biology. In…

Optimization and Control · Mathematics 2016-01-25 Stephane Chretien , Sebastien Darses

Human social networks are inherently multiplex, comprising overlapping layers of relationships. Different layers may have distinct structural properties and interpersonal dynamics, but also may interact to form complex interdependent…

Social and Information Networks · Computer Science 2025-10-22 Yongren Shi , Edo Airoldi , Nicholas A. Christakis

In the domain of network biology, the interactions among heterogeneous genomic and molecular entities are represented through networks. Link prediction (LP) methodologies are instrumental in inferring missing or prospective associations…

Molecular Networks · Quantitative Biology 2023-12-05 Ahmad F. Al Musawi , Satyaki Roy , Preetam Ghosh

Social network structures play an important role in the lives of animals by affecting individual fitness and the spread of disease and information. Nevertheless, we still lack a good understanding of how these structures emerge from the…

Physics and Society · Physics 2026-02-16 Josefine Bohr Brask , Andreas Koher , Darren P. Croft , Sune Lehmann

Coregulation of the expression of groups of genes has been extensively demonstrated empirically in bacterial and eukaryotic systems. Such coregulation can arise through the use of shared regulatory motifs, which allow the coordinated…

Machine Learning · Statistics 2016-04-12 Jonathan H. Warrell , Musa M. Mhlanga

Highly-optimized complex transport networks serve crucial functions in many man-made and natural systems such as power grids and plant or animal vasculature. Often, the relevant optimization functional is non-convex and characterized by…

Biological Physics · Physics 2016-09-23 Henrik Ronellenfitsch , Eleni Katifori

In this paper, controllability of undirected networked systems with {diffusively coupled subsystems} is considered, where each subsystem is of {identically {\emph{fixed}}} general high-order single-input-multi-output dynamics. The…

Systems and Control · Electrical Eng. & Systems 2020-04-21 Yuan Zhang , Yuanqing Xia , Han Gao , Guangchen Zhang

The brain is a complex organ characterized by heterogeneous patterns of structural connections supporting unparalleled feats of cognition and a wide range of behaviors. New noninvasive imaging techniques now allow these patterns to be…

Neurons and Cognition · Quantitative Biology 2020-04-03 Christopher W. Lynn , Danielle S. Bassett

Disordered fibrous networks are ubiquitous in nature as major structural components of living cells and tissues. The mechanical stability of networks generally depends on the degree of connectivity: only when the average number of…

Biological Physics · Physics 2016-06-22 A. Sharma , A. J. Licup , R. Rens , M. Sheinman , K. A. Jansen , G. H. Koenderink , F. C. MacKintosh

Artificial neurons built on synthetic gene networks have potential applications ranging from complex cellular decision-making to bioreactor regulation. Furthermore, due to the high information throughput of natural systems, it provides an…

Neural and Evolutionary Computing · Computer Science 2020-01-31 Sihao Huang