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The analysis of microcirculation images has the potential to reveal early signs of life-threatening diseases like sepsis. Quantifying the capillary density and the capillary distribution in microcirculation images can be used as a…

Computer Vision and Pattern Recognition · Computer Science 2022-05-12 Maged Abdalla Helmy Mohamed Abdou , Trung Tuyen Truong , Eric Jul , Paulo Ferreira

Growing anthropogenic pressures have increased the need for robust predictive models. Meeting this demand requires approaches that can handle bigger data to yield forecasts that capture the variability and underlying uncertainty of…

Quantitative Methods · Quantitative Biology 2024-08-06 EM Wolkovich , T Jonathan Davies , William D Pearse , Michael Betancourt

Simulated microbial communities are used in benchmarking microbial abundance estimators and other bioinformatic utilities. To match current data scales, large simulated samples are needed, and many. The speed of current implementations…

Quantitative Methods · Quantitative Biology 2025-11-20 Amit Lavon

Reproducibility of computational studies is a hallmark of scientific methodology. It enables researchers to build with confidence on the methods and findings of others, reuse and extend computational pipelines, and thereby drive scientific…

Membrane computing is a branch of natural computingwhich abstracts fromthe structure and the functioning of living cells. The computation models obtained in the field of membrane computing are usually called P systems. P systems have been…

Computational Complexity · Computer Science 2023-06-22 Yu Jin , Bosheng Song , Yanyan Li , Ying Zhu

Computer-based learning platforms (CBLPs) have become a common medium in schools, transforming how students learn and interact with educational content. However, researchers still lack adequate tools to address the diverse set of challenges…

From a purely operational standpoint, the existence of microbes that can grow under extreme conditions, or "extremophiles", leads to the question of how the molecules making up these microbes can maintain both their structure and function.…

Soft Condensed Matter · Physics 2016-03-23 Q. Huang , K. N. Tran , J. M. Rodgers , D. H. Bartlett , R. J. Hemley , T. Ichiye

High quality gene models are necessary to expand the molecular and genetic tools available for a target organism, but these are available for only a handful of model organisms that have undergone extensive curation and experimental…

Machine learning (ML) is becoming increasingly crucial in many fields of engineering but has not yet played out its full potential in bioprocess engineering. While experimentation has been accelerated by increasing levels of lab automation,…

Environmental microorganism (EM) offers a high-efficient, harmless, and low-cost solution to environmental pollution. They are used in sanitation, monitoring, and decomposition of environmental pollutants. However, this depends on the…

Computer Vision and Pattern Recognition · Computer Science 2021-02-25 Frank Kulwa , Chen Li , Jinghua Zhang , Kimiaki Shirahama , Sergey Kosov , Xin Zhao , Hongzan Sun , Tao Jiang , Marcin Grzegorzek

Motivation: The availability of thousands of invidual genomes of one species should boost rapid progress in personalized medicine or understanding of the interaction between genotype and phenotype, to name a few applications. A key…

Computational Engineering, Finance, and Science · Computer Science 2017-03-03 Agnieszka Danek , Sebastian Deorowicz , Szymon Grabowski

Social evolutionary theory seeks to explain increases in the scale and complexity of human societies, from origins to present. Over the course of the twentieth century, social evolutionary theory largely fell out of favor as a way of…

Multiagent Systems · Computer Science 2025-02-27 David H. Wolpert , Kyle Harper

Online learners spend millions of hours per year testing their new skills on assignments with known answers. This paper explores whether framing research questions as assignments with unknown answers helps learners generate novel, useful,…

Human-Computer Interaction · Computer Science 2016-09-20 Vineet Pandey , Scott Klemmer , Amnon Amir , Justine Debelius , Embriette R. Hyde , Tomasz Kosciolek , Rob Knight

Lifemapper (http://www.lifemapper.org) is a predictive electronic atlas of the Earth's biological biodiversity. Using a screensaver version of the GARP genetic algorithm for modeling species distributions, Lifemapper harnesses vast…

Quantitative Methods · Quantitative Biology 2011-11-09 David R. B. Stockwell , James H. Beach , Aimee Stewart , Gregory Vorontsov , David Vieglais , Ricardo Scachetti Pereira

Microfluidic droplet screens serve as an innovative platform for high-throughput biotechnology, enabling significant advancements in discovery, product optimization, and analysis. This review sheds light on the emerging trend of interaction…

Quantitative Methods · Quantitative Biology 2023-09-11 Carolus Vitalis , Tobias Wenzel

The necessity for complex calculations in high-energy physics and large-scale data analysis has led to the development of computing grids, such as the ALICE computing grid at CERN. These grids outperform traditional supercomputers but…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-11-20 Jananga Kalawana , Malith Dilshan , Kaveesha Dinamidu , Kalana Wijethunga , Maksim Stortvedt , Indika Perera

This is a thought piece on data-intensive science requirements for databases and science centers. It argues that peta-scale datasets will be housed by science centers that provide substantial storage and processing for scientists who access…

Databases · Computer Science 2007-05-23 Jim Gray , David T. Liu , Maria Nieto-Santisteban , Alexander S. Szalay , David DeWitt , Gerd Heber

In living systems, we often see the emergence of the ingredients necessary for computation -- the capacity for information transmission, storage, and modification -- begging the question of how we may exploit or imitate such biological…

Neurons and Cognition · Quantitative Biology 2020-09-11 Kristine Heiney , Gunnar Tufte , Stefano Nichele

Evaluating modern machine learning models has become prohibitively expensive. Benchmarks such as LMMs-Eval and HELM demand thousands of GPU hours per model. Costly evaluation reduces inclusivity, slows the cycle of innovation, and worsens…

Machine Learning · Computer Science 2026-03-03 Alexander Rubinstein , Benjamin Raible , Martin Gubri , Seong Joon Oh

Microbes are everywhere, including in and on our bodies, and have been shown to play key roles in a variety of prevalent human diseases. Consequently, there has been intense interest in the design of bacteriotherapies or "bugs as drugs,"…

Machine Learning · Statistics 2020-04-13 Travis E. Gibson , Georg K. Gerber
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