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Chronic pancreatitis (CP) is a progressive inflammatory disease frequently associated with severe, treatment-resistant abdominal pain, which is hypothesized to result from pancreatic ductal hypertension (PDH) secondary to ductal strictures…

Medical Physics · Physics 2025-08-22 Haobo Zhao , Jung-Hee Seo , Venkata Akshintala , Surya Evani , Rajat Mittal

Echocardiographers can detect pulmonary hypertension using Doppler echocardiography; however, accurately assessing its progression often proves challenging. Right heart catheterization (RHC), the gold standard for precise evaluation, is…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Jiewen Yang , Taoran Huang , Shangwei Ding , Xiaowei Xu , Qinhua Zhao , Yong Jiang , Jiarong Guo , Bin Pu , Jiexuan Zheng , Caojin Zhang , Hongwen Fei , Xiaomeng Li

Background: We aimed to quantify hepatic vessel volumes across chronic liver disease stages and healthy controls using deep learning-based magnetic resonance imaging (MRI) analysis, and assess correlations with biomarkers for liver…

Pulmonary hypertension (PH), defined by a mean pulmonary arterial pressure (mPAP) $>$ 20 mmHg, is characterized by increased pulmonary vascular resistance and decreased pulmonary arterial compliance. There are few measurable biomarkers of…

Quantitative Methods · Quantitative Biology 2025-06-06 Amanda L. Colunga , Mitchel J. Colebank , REU Program , Mette S. Olufsen

The local beat-to-beat local pulse pressure (PP) and blood pressure waveform of arteries, especially central arteries, are important indicators of the course of cardiovascular diseases (CVDs). Nevertheless, noninvasive measurement of them…

Signal Processing · Electrical Eng. & Systems 2023-05-30 Lirui Xu , Pang Wu , Pan Xia , Fanglin Geng , Peng Wang , Xianxiang Chen , Zhenfeng Li , Lidong Du , Shuping Liu , Li Li , Hongbo Chang , Zhen Fang

Intracardiac flow patterns are shaped by the coupled motion of the cardiac chambers and heart valves and provide important information about cardiac function. However, clinical flow imaging remains limited by exam times, noise, resolution,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Fanwei Kong , Aaron Brown , Michael Loecher , Perry S. Choi , Lei Shi , Michael Ma , Daniel B. Ennis , Alison Marsden

Determining brain hemodynamics plays a critical role in the diagnosis and treatment of various cerebrovascular diseases. In this work, we put forth a physics-informed deep learning framework that augments sparse clinical measurements with…

Medical Physics · Physics 2021-08-27 Mohammad Sarabian , Hessam Babaee , Kaveh Laksari

Accurate noninvasive estimation of intracranial pressure (ICP) remains a major challenge in critical care. We developed a bespoke machine learning algorithm that integrates system identification and ranking-constrained optimization to…

The invasive measurement of the hepatic venous pressure gradient is still considered as the reference method to assess the severity of portal hypertension. Even though previous studies have shown that the liver stiffness measured by…

Computational fluid dynamics (CFD) based simulation of coronary blood flow provides valuable hemodynamic markers, such as pressure gradients, for diagnosing coronary artery disease (CAD). However, CFD is computationally expensive,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Rene Lisasi , Michele Esposito , Chen Zhao

Continuous cardiovascular monitoring can play a key role in precision health. However, some fundamental cardiac biomarkers of interest, including stroke volume and cardiac output, require invasive measurements, e.g., arterial pressure…

Hypertension is a leading cause of morbidity and mortality worldwide. The ability to diagnose and treat hypertension in the ambulatory population is hindered by limited access and poor adherence to current methods of monitoring blood…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Theodore Curran , Chengqian Ma , Xin Liu , Daniel McDuff , Girish Narayanswamy , George Stergiou , Shwetak Patel , Eugene Yang

Cardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide, and sustained hypertension is an often silent risk factor, making cuffless continuous blood pressure (BP) monitoring with wearable devices important for…

Signal Processing · Electrical Eng. & Systems 2025-12-02 Yiqiao Chen , Fazheng Xu , Zijian Huang , Juchi He , Zhenghui Feng

Hypertension (HPT) refers to a condition where the pressure exerted on the walls of arteries by blood pumped from the heart to the body reaches levels that can lead to various ailments. Annually, a significant number of lives are lost…

Signal Processing · Electrical Eng. & Systems 2023-11-08 Yunus Emre Erdoğan , Ali Narin , Walid Hariri

Hypertension is a medical condition characterized by high blood pressure, and classifying it into its various stages is crucial to managing the disease. In this project, a novel method is proposed for classifying stages of hypertension…

Machine Learning · Computer Science 2023-04-17 Graham Frederick , Yaswant T , Brintha Therese A

Pulmonary Hypertension (PH) is a severe disease characterized by an elevated pulmonary artery pressure. The gold standard for PH diagnosis is measurement of mean Pulmonary Artery Pressure (mPAP) during an invasive Right Heart…

Image and Video Processing · Electrical Eng. & Systems 2023-12-25 Michal K. Grzeszczyk , Tadeusz Satlawa , Angela Lungu , Andrew Swift , Andrew Narracott , Rod Hose , Tomasz Trzcinski , Arkadiusz Sitek

Intracranial pressure (ICP) elevation poses severe threats to cerebral function, thus necessitating monitoring for timely intervention. While lumbar puncture is the gold standard for ICP measurement, its invasiveness and associated risks…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Pengxu Wen , Tingting Yu , Ziwei Nie , Cheng Jiang , Zhenyu Yin , Mingyang He , Bo Liao , Xiaoping Yang

Accurate carotid plaque grading (CPG) is vital to assess the risk of cardiovascular and cerebrovascular diseases. Due to the small size and high intra-class variability of plaque, CPG is commonly evaluated using a combination of transverse…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Zhiyuan Zhu , Jian Wang , Yong Jiang , Tong Han , Yuhao Huang , Ang Zhang , Kaiwen Yang , Mingyuan Luo , Zhe Liu , Yaofei Duan , Dong Ni , Tianhong Tang , Xin Yang

Hypertension is a potentially unsafe health ailment, which can be indicated directly from the Blood pressure (BP). Hypertension always leads to other health complications. Continuous monitoring of BP is very important; however, cuff-based…

Exploiting photoplethysmography signals (PPG) for non-invasive blood pressure (BP) measurement is interesting for various reasons. First, PPG can easily be measured using fingerclip sensors. Second, camera-based approaches allow to derive…

Machine Learning · Computer Science 2021-04-20 Fabian Schrumpf , Patrick Frenzel , Christoph Aust , Georg Osterhoff , Mirco Fuchs
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