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Purpose: To develop a motion-robust and geometrically-accurate quantitative CEST approach using radial k-space sampling, locally low-rank reconstruction and neural network quantification. Methods: The acquisition schedule was generated via…
Purpose: To develop a model-based deep neural network for high-quality image reconstruction of undersampled multi-coil chemical exchange saturation transfer (CEST) data. Theory and Methods: Inspired by the variational network, the CEST…
Purpose: To develop a fast magnetic resonance fingerprinting (MRF) method for quantitative chemical exchange saturation transfer (CEST) imaging. Methods: We implemented a CEST-MRF method to quantify the chemical exchange rate and volume…
$\textbf{Purpose}$: To develop a clinical CEST MR fingerprinting (CEST-MRF) method for brain tumor quantification using EPI acquisition and deep learning reconstruction. $\textbf{Methods}$: A CEST-MRF pulse sequence originally designed for…
Purpose: To understand the influence of various acquisition parameters on the ability of CEST MR-Fingerprinting (MRF) to discriminate different chemical exchange parameters and to provide tools for optimal acquisition schedule design and…
CEST suffers from two main problems long acquisitin times or restricted coverage as well as incoherent protocol settings. In this paper we give suggestions on how to optimise your protocol settings fro CEST and present one setting for APT…
Purpose: To develop and validate a framework for rapid, accurate, and reproducible whole-brain, multi-pool chemical exchange saturation transfer (CEST) imaging at 3T, addressing challenges of long acquisition times and confounding factors.…
Machine learning (ML) has been increasingly used to quantify chemical exchange saturation transfer (CEST) effect. ML models are typically trained using either measured data or fully simulated data. However, training with measured data often…
Purpose: This work proposes a method for the simultaneous estimation of the exchange-dependent relaxation rate Rex and the longitudinal relaxation time T1 from a single acquisition. Methods: A novel acquisition scheme was developed that…
Purpose: Separation of different CEST signals in the Z-spectrum is a challenge especially at low field strengths where amide, amine, and NOE peaks coalesce with each other or with the water peak. The purpose of this work is to investigate…
Machine learning-based interatomic potentials and force fields depend critically on accurate atomic structures, yet such data are scarce due to the limited availability of experimentally resolved crystals. Although atomic-resolution…
Chemical exchange saturation transfer (CEST) MRI is a non-invasive imaging modality for detecting metabolites. It offers higher resolution and sensitivity compared to conventional magnetic resonance spectroscopy (MRS). However,…
Chemical Exchange Saturation Transfer (CEST) MRI demonstrates its capability in significantly enhancing the detection of proteins and metabolites with low concentrations through exchangeable protons. The clinical application of CEST,…
The onset of rheumatic diseases such as rheumatoid arthritis is typically subclinical, which results in challenging early detection of the disease. However, characteristic changes in the anatomy can be detected using imaging techniques such…
Patient motion during PET is inevitable. Its long acquisition time not only increases the motion and the associated artifacts but also the patient's discomfort, thus PET acceleration is desirable. However, accelerating PET acquisition will…
Endogenous chemical exchange saturation transfer (CEST) effects are always diluted by competing effects such as direct water proton saturation (spillover) and macromolecular magnetization transfer (MT). This leads to T2-and MT-shine-through…
Block compressive sensing is a well-known signal acquisition and reconstruction paradigm with widespread application prospects in science, engineering and cybernetic systems. However, state-of-the-art block-based image compressive sensing…
SPECT (Single-photon Emission Computerized Tomography) and PET (Positron Emission Tomography) are essential medical imaging tools, for which the sampling angle number, scan time should be chosen carefully to compromise between image quality…
We propose a magnetic resonance (MR)-based method for estimation of continuous linear attenuation coefficients (LAC) in positron emission tomography (PET) using a physical compartmental model and ultrashort echo time (UTE)/multi-echo Dixon…
We present a conditional estimation (CEST) framework to learn 3D facial parameters from 2D single-view images by self-supervised training from videos. CEST is based on the process of analysis by synthesis, where the 3D facial parameters…