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Histo-pathological diagnostics are an inherent part of the everyday work but are particularly laborious and associated with time-consuming manual analysis of image data. In order to cope with the increasing diagnostic case numbers due to…
Single-cell transcriptomics and proteomics have become a great source for data-driven insights into biology, enabling the use of advanced deep learning methods to understand cellular heterogeneity and gene expression at the single-cell…
Accurate classification of haematological cells is critical for diagnosing blood disorders, but presents significant challenges for machine automation owing to the complexity of cell morphology, heterogeneities of biological, pathological,…
Cell detection, segmentation and classification are essential for analyzing tumor microenvironments (TME) on hematoxylin and eosin (H&E) slides. Existing methods suffer from poor performance on understudied cell types (rare or not present…
Blood cell classification and counting are vital for the diagnosis of various blood-related diseases, such as anemia, leukemia, and thrombocytopenia. The manual process of blood cell classification and counting is time-consuming, prone to…
The diagnosis of blood-based diseases often involves identifying and characterizing patient blood samples. Automated methods to detect and classify blood cell subtypes have important medical applications. Automated medical image processing…
Malignant lymphoma subtype classification directly impacts treatment strategies and patient outcomes, necessitating classification models that achieve both high accuracy and sufficient explainability. This study proposes a novel explainable…
Hepatocellular carcinoma (HCC) is a common type of liver cancer whose early-stage diagnosis is a common challenge, mainly due to the manual assessment of hematoxylin and eosin-stained whole slide images, which is a time-consuming process…
Immunofluorescent (IF) imaging is crucial for visualizing biomarker expressions, cell morphology and assessing the effects of drug treatments on sub-cellular components. IF imaging needs extra staining process and often requiring cell…
Automatic lymph node (LN) segmentation and detection for cancer staging are critical. In clinical practice, computed tomography (CT) and positron emission tomography (PET) imaging detect abnormal LNs. Despite its low contrast and variety in…
Machine learning has endless applications in the health care industry. White blood cell classification is one of the interesting and promising area of research. The classification of the white blood cells plays an important part in the…
Cancer is the uncontrollable cell division of abnormal cells inside the human body, which can spread to other body organs. It is one of the non-communicable diseases (NCDs) and NCDs accounts for 71% of total deaths worldwide whereas lung…
Explainability is a key requirement for computer-aided diagnosis systems in clinical decision-making. Multiple instance learning with attention pooling provides instance-level explainability, however for many clinical applications a deeper,…
Accurate skin cancer diagnosis is vital for early treatment and improved patient outcomes. Deep learning (DL) models have shown promise in automating skin cancer classification, yet challenges remain due to data scarcity and limited…
Pigmented skin lesions represent localized areas of increased melanin and can indicate serious conditions like melanoma, a major contributor to skin cancer mortality. The MedMNIST v2 dataset, inspired by MNIST, was recently introduced to…
An automatic evidential segmentation method based on Dempster-Shafer theory and deep learning is proposed to segment lymphomas from three-dimensional Positron Emission Tomography (PET) and Computed Tomography (CT) images. The architecture…
Motivation: Tumor classification using Imaging Mass Spectrometry (IMS) data has a high potential for future applications in pathology. Due to the complexity and size of the data, automated feature extraction and classification steps are…
Acute lymphoblastic leukemia (ALL) severity is determined by the presence and ratios of blast cells (abnormal white blood cells) in both bone marrow and peripheral blood. Manual diagnosis of this disease is a tedious and time-consuming…
Breast cancer is a health problem that affects mainly the female population. An early detection increases the chances of effective treatment, improving the prognosis of the disease. In this regard, computational tools have been proposed to…
Orthopoxvirus infections must be accurately classified from medical pictures for an easy and early diagnosis and epidemic prevention. The necessity for automated and scalable solutions is highlighted by the fact that traditional diagnostic…