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Estimating externally valid causal effects is a foundational problem in the social and biomedical sciences. Generalizing or transporting causal estimates from an experimental sample to a target population of interest relies on an overlap…

Methodology · Statistics 2024-03-29 Melody Huang

We propose Black Box Explanations through Transparent Approximations (BETA), a novel model agnostic framework for explaining the behavior of any black-box classifier by simultaneously optimizing for fidelity to the original model and…

Artificial Intelligence · Computer Science 2017-07-06 Himabindu Lakkaraju , Ece Kamar , Rich Caruana , Jure Leskovec

Local explainability methods -- those which seek to generate an explanation for each prediction -- are becoming increasingly prevalent due to the need for practitioners to rationalize their model outputs. However, comparing local…

Machine Learning · Computer Science 2022-01-07 Peter Xenopoulos , Gromit Chan , Harish Doraiswamy , Luis Gustavo Nonato , Brian Barr , Claudio Silva

Surrogate markers are most commonly studied within the context of randomized clinical trials. However, the need for alternative outcomes extends beyond these settings and may be more pronounced in real-world public health and social science…

Methodology · Statistics 2025-04-23 Rebecca Knowlton , Layla Parast

Explainable AI has become a common term in the literature, scrutinized by computer scientists and statisticians and highlighted by psychological or philosophical researchers. One major effort many researchers tackle is constructing general…

Artificial Intelligence · Computer Science 2025-09-12 Carina Newen , Daniel Bodemer , Sonja Glantz , Emmanuel Müller , Magdalena Wischnewski , Lenka Schnaubert

Black box systems for automated decision making, often based on machine learning over (big) data, map a user's features into a class or a score without exposing the reasons why. This is problematic not only for lack of transparency, but…

Artificial Intelligence · Computer Science 2018-06-27 Dino Pedreschi , Fosca Giannotti , Riccardo Guidotti , Anna Monreale , Luca Pappalardo , Salvatore Ruggieri , Franco Turini

As the use of deep learning techniques has grown across various fields over the past decade, complaints about the opaqueness of the black-box models have increased, resulting in an increased focus on transparency in deep learning models.…

Computation and Language · Computer Science 2024-03-19 Siwen Luo , Hamish Ivison , Caren Han , Josiah Poon

In many real-world causal inference applications, the primary outcomes (labels) are often partially missing, especially if they are expensive or difficult to collect. If the missingness depends on covariates (i.e., missingness is not…

Machine Learning · Statistics 2024-05-24 Zhenghao Zeng , David Arbour , Avi Feller , Raghavendra Addanki , Ryan Rossi , Ritwik Sinha , Edward H. Kennedy

When the primary outcome is hard to collect, surrogate endpoint is typically used as a substitute. However, even when the treatment has a positive average causal effect (ACE) on the surrogate endpoint, which also has a positive ACE on the…

Statistics Theory · Mathematics 2016-07-20 Yunjian Yin , Lan Liu , Zhi Geng , Peng Luo

It is known that recommendations of AI-based systems can be incorrect or unfair. Hence, it is often proposed that a human be the final decision-maker. Prior work has argued that explanations are an essential pathway to help human…

Human-Computer Interaction · Computer Science 2022-05-10 Jakob Schoeffer , Maria De-Arteaga , Niklas Kuehl

In situations where explanations of black-box models may be useful, the fairness of the black-box is also often a relevant concern. However, the link between the fairness of the black-box model and the behavior of explanations for the…

Machine Learning · Computer Science 2021-06-28 Jessica Dai , Sohini Upadhyay , Stephen H. Bach , Himabindu Lakkaraju

Machine learning surrogates are increasingly employed to replace expensive computational models for physics-based reliability analysis. However, their use introduces epistemic uncertainty from model approximation errors, which couples with…

Machine Learning · Computer Science 2025-09-24 Amirreza Tootchi , Xiaoping Du

Offline optimization is an important task in numerous material engineering domains where online experimentation to collect data is too expensive and needs to be replaced by an in silico maximization of a surrogate of the black-box function.…

Machine Learning · Computer Science 2025-03-07 Manh Cuong Dao , Phi Le Nguyen , Thao Nguyen Truong , Trong Nghia Hoang

We present a framework for automatically structuring and training fast, approximate, deep neural surrogates of stochastic simulators. Unlike traditional approaches to surrogate modeling, our surrogates retain the interpretable structure and…

Trustworthy machine learning is driving a large number of ML community works in order to improve ML acceptance and adoption. The main aspect of trustworthy machine learning are the followings: fairness, uncertainty, robustness,…

Machine Learning · Computer Science 2022-07-08 Gregory Scafarto , Nicolas Posocco , Antoine Bonnefoy

This paper provides empirical concerns about post-hoc explanations of black-box ML models, one of the major trends in AI explainability (XAI), by showing its lack of interpretability and societal consequences. Using a representative…

Human-Computer Interaction · Computer Science 2021-10-01 Jean-Marie John-Mathews

Many proposed applications of neural networks in machine learning, cognitive/brain science, and society hinge on the feasibility of inner interpretability via circuit discovery. This calls for empirical and theoretical explorations of…

Artificial Intelligence · Computer Science 2025-04-02 Federico Adolfi , Martina G. Vilas , Todd Wareham

Whilst an abundance of techniques have recently been proposed to generate counterfactual explanations for the predictions of opaque black-box systems, markedly less attention has been paid to exploring the uncertainty of these generated…

Machine Learning · Computer Science 2021-07-22 Eoin Delaney , Derek Greene , Mark T. Keane

Complex engineering models are typically computationally demanding and defined by a high-dimensional parameter space challenging the comprehensive exploration of parameter effects and design optimization. To overcome this curse of…

Applications · Statistics 2024-03-01 Corey Arndt , Cody Crusenberry , Bozhi Heng , Rochelle Butler , Stephanie TerMaath

As machine learning and algorithmic decision making systems are increasingly being leveraged in high-stakes human-in-the-loop settings, there is a pressing need to understand the rationale of their predictions. Researchers have responded to…

Machine Learning · Computer Science 2020-12-07 Jonathan Dinu , Jeffrey Bigham , J. Zico Kolter