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The aim of this chapter is to provide a brief introduction into the basics of a top-down multilevel tumor dynamics modeling method primarily based on discrete entity consideration and manipulation. The method is clinically oriented, one of…

Medical Physics · Physics 2010-09-14 Georgios Stamatakos

The advent of dispersion-engineered and highly nonlinear nanophotonics is expected to open up an all-optical path towards the strong-interaction regime of quantum optics by combining high transverse field confinement with ultra-short-pulse…

Quantum Physics · Physics 2021-03-09 Ryotatsu Yanagimoto , Edwin Ng , Tatsuhiro Onodera , Hideo Mabuchi

The rapid advances in 3D scanning and acquisition techniques have given rise to the explosive increase of volumetric digital models in recent years. This dissertation systematically trailblazes a novel volumetric modeling framework to…

Graphics · Computer Science 2013-08-06 Bo Li

Mammography is a vital screening technique for early revealing and identification of breast cancer in order to assist to decrease mortality rate. Practical applications of mammograms are not limited to breast cancer revealing,…

Image and Video Processing · Electrical Eng. & Systems 2020-10-08 Aparna Bhale , Manish Joshi

Miniaturized spectrometry system is playing an essential role for materials analysis in the development of in-situ or portable sensing platforms across research and industry. However, there unavoidably exists trade-offs between the…

Materials with thickness ranging from a few nanometers to a single atomic layer present unprecedented opportunities to investigate new phases of matter constrained to the two-dimensional plane.Particle-particle Coulomb interaction is…

Mesoscale and Nanoscale Physics · Physics 2021-10-27 A. Carvalho , P. E. Trevisanutto , S. Taioli , A. H. Castro Neto

The applicability of computational models to the biological world is an active topic of debate. We argue that a useful path forward results from abandoning hard boundaries between categories and adopting an observer-dependent, pragmatic…

Multiagent Systems · Computer Science 2022-12-22 Joshua Bongard , Michael Levin

Due to their chemical and structural diversity, nanoporous materials can be used in a wide variety of applications, including fluid separation, gas storage, heterogeneous catalysis, drug delivery, etc. Given the large and rapidly increasing…

Materials Science · Physics 2022-06-20 Emmanuel Ren , Philippe Guilbaud , François-Xavier Coudert

We propose a general multiscale approach for the mechanical behavior of three-dimensional networks of macromolecules undergoing strain-induced unfolding. Starting from a (statistically based) energetic analysis of the macromolecule…

Soft Condensed Matter · Physics 2015-06-22 Domenico De Tommasi , Giuseppe Puglisi , Giuseppe Saccomandi

Recently, there has been a resurgence of interest in rigorous algorithms for the inference of cancer progression from genomic data. The motivations are manifold: (i) growing NGS and single cell data from cancer patients, (ii) need for novel…

Machine Learning · Computer Science 2016-02-25 Daniele Ramazzotti

We describe a software toolbox for the configuration of deep neural networks in the domain of skin cancer classification. The implemented software architecture allows developers to quickly set up new convolutional neural network (CNN)…

Image and Video Processing · Electrical Eng. & Systems 2019-08-23 Fabrizio Nunnari , Daniel Sonntag

Metasurfaces -- ultrathin structures composed of subwavelength optical elements -- have revolutionized light manipulation by enabling precise control over electromagnetic waves' amplitude, phase, polarization, and spectral properties.…

Optics · Physics 2024-11-15 Charles Roques-Carmes , Kai Wang , Yuanmu Yang , Arka Majumdar , Zin Lin

Diffusion models have emerged as a powerful new family of deep generative models with record-breaking performance in many applications, including image synthesis, video generation, and molecule design. In this survey, we provide an overview…

Machine Learning · Computer Science 2025-09-30 Ling Yang , Zhilong Zhang , Yang Song , Shenda Hong , Runsheng Xu , Yue Zhao , Wentao Zhang , Bin Cui , Ming-Hsuan Yang

A systematic understanding of the evolution and growth dynamics of invasive solid tumors in response to different chemotherapy strategies is crucial for the development of individually optimized oncotherapy. Here, we develop a hybrid…

Tissues and Organs · Quantitative Biology 2020-07-01 Hang Xie , Yang Jiao , Qihui Fan , Miaomiao Hai , Jiaen Yang , Zhijian Hu , Yue Yang , Jianwei Shuai , Guo Chen , Ruchuan Liu , Liyu Liu

Early cancer detection remains one of the most critical challenges in modern healthcare, where delayed diagnosis significantly reduces survival outcomes. Recent advancements in artificial intelligence, particularly deep learning, have…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Emmanuella Avwerosuoghene Oghenekaro

Nuclear Magnetic Resonance (NMR) and Magnetic Resonance Imaging (MRI) represent versatile tools with diverse applications spanning physics, chemistry, geology, and medical science. This comprehensive review explores the foundational…

Medical Physics · Physics 2024-03-07 Islam G. Ali

The speed and the versatility of today's computers open up new opportunities to simulate complex biological systems. Here we review a computational approach recently proposed by us to model large tumor cell populations and spheroids, and we…

Tissues and Organs · Quantitative Biology 2010-12-13 Roberto Chignola , Alessio Del Fabbro , Marcello Farina , Edoardo Milotti

The goal of cancer immunotherapy is to boost a patient's immune response to a tumor. Yet, the design of an effective immunotherapy is complicated by various factors, including a potentially immunosuppressive tumor microenvironment,…

Tissues and Organs · Quantitative Biology 2017-06-29 Anna Konstorum , Anthony T. Vella , Adam J. Adler , Reinhard Laubenbacher

Computational models and simulations are not just appealing because of their intrinsic characteristics across spatiotemporal scales, scalability, and predictive power, but also because the set of problems in cancer biomedicine that can be…

Tissues and Organs · Quantitative Biology 2023-11-01 Nicolò Cogno , Cristian Axenie , Roman Bauer , Vasileios Vavourakis

Research in neural models inspired by mammal's visual cortex has led to many spiking neural networks such as pulse-coupled neural networks (PCNNs). These models are oscillating, spatio-temporal models stimulated with images to produce…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Nurul Rafi , Pablo Rivas
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