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The human microbiome is a complex ecological system, and describing its structure and function under different environmental conditions is important from both basic scientific and medical perspectives. Viewed through a biostatistical lens,…

Applications · Statistics 2017-11-17 Kris Sankaran , Susan P. Holmes

Deep latent generative models have attracted increasing attention due to the capacity of combining the strengths of deep learning and probabilistic models in an elegant way. The data representations learned with the models are often…

Machine Learning · Computer Science 2023-04-04 Zhao Xu , Daniel Onoro Rubio , Giuseppe Serra , Mathias Niepert

In this paper we develop a novel approach for estimating large and sparse dynamic factor models using variational inference, also allowing for missing data. Inspired by Bayesian variable selection, we apply slab-and-spike priors onto the…

Methodology · Statistics 2022-10-14 Erik Spånberg

Deep generative models like VAEs and diffusion models have advanced various generation tasks by leveraging latent variables to learn data distributions and generate high-quality samples. Despite the field of explainable AI making strides in…

Machine Learning · Computer Science 2025-12-22 Mengdan Zhu , Raasikh Kanjiani , Jiahui Lu , Andrew Choi , Qirui Ye , Liang Zhao

The techniques suggested in Fr\"uhwirth-Schnatter et al. (2024) concern sparsity and factor selection and have enormous potential beyond standard factor analysis applications. We show how these techniques can be applied to Latent Space (LS)…

Methodology · Statistics 2024-11-15 Roberto Casarin , Antonio Peruzzi

Large language models possess strong chemical reasoning capabilities, making them effective molecular editors. However, property-relevant information is implicitly entangled across their dense hidden states, providing no explicit handle for…

Machine Learning · Computer Science 2026-05-12 Mingxu Zhang , Yuhan Li , Lujundong Li , Dazhong Shen , Hui Xiong , Ying Sun

Structured prediction requires manipulating a large number of combinatorial structures, e.g., dependency trees or alignments, either as latent or output variables. Recently, the SparseMAP method has been proposed as a differentiable, sparse…

Machine Learning · Computer Science 2020-08-06 Vlad Niculae , André F. T. Martins

Suppose we observe samples of a subset of a collection of random variables. No additional information is provided about the number of latent variables, nor of the relationship between the latent and observed variables. Is it possible to…

Statistics Theory · Mathematics 2012-11-05 Venkat Chandrasekaran , Pablo A. Parrilo , Alan S. Willsky

Current supervised learning can learn spurious correlation during the data-fitting process, imposing issues regarding interpretability, out-of-distribution (OOD) generalization, and robustness. To avoid spurious correlation, we propose a…

Machine Learning · Computer Science 2021-04-29 Xinwei Sun , Botong Wu , Xiangyu Zheng , Chang Liu , Wei Chen , Tao Qin , Tie-yan Liu

Partial domain adaptation which assumes that the unknown target label space is a subset of the source label space has attracted much attention in computer vision. Despite recent progress, existing methods often suffer from three key…

Computer Vision and Pattern Recognition · Computer Science 2023-01-05 Aadarsh Sahoo , Rameswar Panda , Rogerio Feris , Kate Saenko , Abir Das

Sparse linear models are one of several core tools for interpretable machine learning, a field of emerging importance as predictive models permeate decision-making in many domains. Unfortunately, sparse linear models are far less flexible…

Machine Learning · Statistics 2024-01-03 Ryan Thompson , Amir Dezfouli , Robert Kohn

Steering has emerged as a promising approach in controlling large language models (LLMs) without modifying model parameters. However, most existing steering methods rely on large-scale datasets to learn clear behavioral information, which…

Machine Learning · Computer Science 2025-10-06 Anyi Wang , Xuansheng Wu , Dong Shu , Yunpu Ma , Ninghao Liu

Supervised models of NLP rely on large collections of text which closely resemble the intended testing setting. Unfortunately matching text is often not available in sufficient quantity, and moreover, within any domain of text, data is…

Computation and Language · Computer Science 2019-06-10 Yitong Li , Timothy Baldwin , Trevor Cohn

Discovering latent representations of the observed world has become increasingly more relevant in data analysis. Much of the effort concentrates on building latent variables which can be used in prediction problems, such as classification…

Machine Learning · Computer Science 2010-01-08 Ricardo Silva

The identification of latent mediator variables is typically conducted using standard structural equation models (SEMs). When SEM is applied to mediation analysis with a causal interpretation, valid inference relies on the strong assumption…

Methodology · Statistics 2025-10-02 Sofia Morelli , Roberto Faleh , Holger Brandt

We propose a statistical framework built on latent variable modeling for scaling laws of large language models (LLMs). Our work is motivated by the rapid emergence of numerous new LLM families with distinct architectures and training…

This paper focuses on the identification of graphical autoregressive models with dynamical latent variables. The dynamical structure of latent variables is described by a matrix polynomial transfer function. Taking account of the sparse…

Methodology · Statistics 2023-07-24 Junyao You , Chengpu Yu

Sparse autoencoders (SAEs) have recently emerged as a powerful tool for interpreting the internal representations of large language models (LLMs), revealing latent latent features with semantical meaning. This interpretability has also…

Other Quantitative Biology · Quantitative Biology 2025-07-11 Haoxiang Guan , Jiyan He , Jie Zhang

We introduce a new approach to prediction in graphical models with latent-shift adaptation, i.e., where source and target environments differ in the distribution of an unobserved confounding latent variable. Previous work has shown that as…

Machine Learning · Statistics 2023-06-26 William I. Walker , Arthur Gretton , Maneesh Sahani

Originally designed to model text, topic modeling has become a powerful tool for uncovering latent structure in domains including medicine, finance, and vision. The goals for the model vary depending on the application: in some cases, the…

Machine Learning · Statistics 2014-11-24 Finale Doshi-Velez , Byron Wallace , Ryan Adams