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We present a model for mechanically-induced pattern formation in growing biological tissues and discuss its application to the development of leaf venation networks. Drawing an analogy with phase transitions in solids, we use a phase field…

Soft Condensed Matter · Physics 2010-10-29 F. Corson , H. Henry , M. Adda-Bedia

Finding the most powerful node in a dynamic random network, the largest set in a partition-valued stochastic process, or the largest family in an evolving population at a given time, can be a very difficult problem. This is particularly the…

Probability · Mathematics 2020-09-09 Cécile Mailler , Peter Mörters , Anna Senkevich

We present some existence results for three-dimensional quasistatic morphoelasticity. The state of the growing body is described by its deformation and the underlying growth tensor and is ruled by the interplay of hyperelastic energy…

Analysis of PDEs · Mathematics 2021-11-23 Elisa Davoli , Katerina Nik , Ulisse Stefanelli

We investigate avascular tumour growth as a two-phase process consisting of cells and liquid. Based on the one-dimensional continuum moving-boundary model formulated by (Byrne, King, McElwain, Preziosi, Applied Mathematics Letters, 2003,…

Analysis of PDEs · Mathematics 2020-06-24 Andrea Genovese de Oliveira , John R. King

The growth of plants is a hydromechanical phenomenon in which cells enlarge by absorbing water, while their walls expand and remodel under turgor-induced tension. In multicellular tissues, where cells are mechanically interconnected,…

Biological Physics · Physics 2025-09-09 Hadrien Oliveri , Ibrahim Cheddadi

We consider a stochastic individual-based model of adaptive dynamics for an asexually reproducing population with mutation, with linear birth and death rates, as well as a density-dependent competition. To depict repeating changes of the…

Populations and Evolution · Quantitative Biology 2025-05-28 Manuel Esser , Anna Kraut

The present work is related to anisotropic cosmological evolution in metric $f(R)$ theory of gravity. The initial part of the paper develops the general cosmological dynamics of homogeneous anisotropic Bianchi-I spacetime in $f(R)$…

General Relativity and Quantum Cosmology · Physics 2019-01-23 Kaushik Bhattacharya , Saikat Chakraborty

We consider a macroscopic model for the growth of living tissues incorporating pressure-driven dispersal and pressure-modulated proliferation. Assuming a power-law relation between the mechanical pressure and the cell density, the model can…

Analysis of PDEs · Mathematics 2024-03-29 Tomasz Dębiec , Piotr Gwiazda , Błażej Miasojedow , Zuzanna Szymańska

Many properties of soft contact interfaces are controlled by the contact area (e.g. friction, contact stiffness and surface charge generation). The contact area increases with the contact age at rest. In contrast, it usually reduces under…

Soft Condensed Matter · Physics 2024-10-31 Bo Zhang , Mariana de Souza , Daniel M. Mulvihill , Davy Dalmas , Julien Scheibert , Yang Xu

Surface growth, by association or dissociation of material on the boundaries of a body, is ubiquitous in both natural and engineering systems. It is the fundamental mechanism by which biological materials grow, starting from the level of a…

Soft Condensed Matter · Physics 2019-03-06 Rami Abi-Akl , Rohan Abeyaratne , Tal Cohen

This paper introduces a model for the mechanical response of anisotropic soft materials undergoing large inelastic deformations. The composite is constituted by a soft isotropic matrix reinforced with stiff fibres, that can evolve…

Soft Condensed Matter · Physics 2022-07-25 Jacopo Ciambella , Paola Nardinocchi

Morphogenesis involves complex shape changes of biological tissues. Yet, tissue shape changes depend on tissue rheology, which in turn arises from the interplay of large numbers of cells. Here, we link cell- and tissue-scale mechanics by…

Soft Condensed Matter · Physics 2026-02-27 Shalabh Kumar Anand , Matthias Merkel

Healing of soft biological tissue is the process of self-recovering or self-repairing the injured or damaged extracellular matrix (ECM). Healing is assumed to be stress-driven, with the objective of returning to a homeostatic stress metrics…

Medical Physics · Physics 2019-12-17 Yiqian He , Di Zuo , Klaus Hackl , Haitian Yang , S. Jamaleddin Mousavi , Stéphane Avril

Plant morphology emerges from cellular growth and structure. The turgor-driven diffuse growth of a cell can be highly anisotropic: significant longitudinally and negligible radially. Such anisotropy is ensured by cellulose microfibrils…

Quantitative Methods · Quantitative Biology 2022-08-23 Jeevanjyoti Chakraborty , Jingxi Luo , Rosemary J Dyson

Tissue growth underpins a wide array of biological and developmental processes, and numerical modeling of growing systems has been shown to be a useful tool for understanding these processes. However, the phenomena that can be captured are…

Soft Condensed Matter · Physics 2023-11-08 Andrew Killeen , Benjamin Partridge , Thibault Bertrand , Chiu Fan Lee

Connecting cell behavior to tissue shape and mechanics is a key challenge in the physics of morphogenesis. Cytoskeletal turnover precludes a fixed reference state, and tensions are actively generated independently of strain; so conventional…

Soft Condensed Matter · Physics 2026-05-28 Nikolas H. Claussen , Fridtjof Brauns , Boris I. Shraiman

Remodelling of biological tissue, due to changes in microstructure, is treated in the continuum mechanical setting. Microstructural change is expressed as an evolution of the reference configuration. This evolution is expressed as a…

Quantitative Methods · Quantitative Biology 2007-05-23 K. Garikipati , H. Narayanan , E. M. Arruda , K. Grosh , S. Calve

In the context of higher-dimensional cosmologies with isotropic visible and internal space and multi-perfect fluid matter, we study the conditions under which adiabatic expansion of the visoble external space is possible, when a…

General Relativity and Quantum Cosmology · Physics 2015-06-25 K. Kleidis , D. B. Papadopoulos

Thermal equilibrium properties of nanoscale systems deviate from standard macroscopic predictions due to a non-negligible coupling to the environment. For anisotropic three-dimensional materials, we derive the mean force corrections to the…

Statistical Mechanics · Physics 2024-01-04 Felix Hartmann , Stefano Scali , Janet Anders

We investigate the Green function of two-dimensional dense random packings of grains in order to discriminate between the different theories of stress transmission in granular materials. Our computer simulations allow for a detailed…

Soft Condensed Matter · Physics 2009-11-11 N. Gland , P. Wang , Hernan A. Makse