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In neuroimaging, extensive post-processing of resting-state functional MRI (rfMRI) data is necessary for its application and investigation in relation to brain-behavior associations. Such post-processing is used to derive brain…

Computational Geometry · Computer Science 2025-09-11 Ty Easley , Kevin Freese , Elizabeth Munch , Janine Bijsterbosch

With the rapid growth of modern technology, many large-scale biomedical studies have been/are being/will be conducted to collect massive datasets with large volumes of multi-modality imaging, genetic, neurocognitive, and clinical…

Methodology · Statistics 2018-03-07 Farouk S. Nathoo , Linglong Kong , Hongtu Zhu

The segmentation of lesions in Moderate to Severe Traumatic Brain Injury (msTBI) presents a significant challenge in neuroimaging due to the diverse characteristics of these lesions, which vary in size, shape, and distribution across brain…

Computer Vision and Pattern Recognition · Computer Science 2025-04-10 Constantin Ulrich , Tassilo Wald , Fabian Isensee , Klaus H. Maier-Hein

Magnetic resonance imaging (MRI) is a crucial tool to identify brain abnormalities in a wide range of neurological disorders. In focal epilepsy MRI is used to identify structural cerebral abnormalities. For covert lesions, machine learning…

Cytoarchitectonic mapping provides anatomically grounded parcellations of brain structure and forms a foundation for integrative, multi-modal neuroscience analyses. These parcellations are defined based on the shape, density, and spatial…

Image and Video Processing · Electrical Eng. & Systems 2026-01-16 Shiqi Zhang , Fang Xu , Pengcheng Zhou

Understanding distinct neurological aging patterns across various populations is vital in the context of a globally aging populace. This study seeks to unravel the structural variations in the aging brain, taking into consideration…

Neurons and Cognition · Quantitative Biology 2024-08-15 Alphin J Thottupattu , Jayanthi Sivaswamy , Bharath Holla , Jithender Saini

Purpose: Conventional automated segmentation of the head anatomy in MRI distinguishes different brain and non-brain tissues based on image intensities and prior tissue probability maps (TPM). This works well for normal head anatomies, but…

Image and Video Processing · Electrical Eng. & Systems 2021-05-20 Lukas Hirsch , Yu Huang , Lucas C Parra

Accurate brain tissue segmentation in Magnetic Resonance Imaging (MRI) has attracted the attention of medical doctors and researchers since variations in tissue volume help in diagnosing and monitoring neurological diseases. Several…

Computer Vision and Pattern Recognition · Computer Science 2019-07-30 Jose Bernal , Kaisar Kushibar , Mariano Cabezas , Sergi Valverde , Arnau Oliver , Xavier Lladó

Computational neuroimaging involves analyzing brain images or signals to provide mechanistic insights and predictive tools for human cognition and behavior. While diffusion models have shown stability and high-quality generation in natural…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Haokai Zhao , Haowei Lou , Lina Yao , Wei Peng , Ehsan Adeli , Kilian M Pohl , Yu Zhang

Brain tumors require an assessment to ensure timely diagnosis and effective patient treatment. Morphological factors such as size, location, texture, and variable appearance complicate tumor inspection. Medical imaging presents challenges,…

Computer Vision and Pattern Recognition · Computer Science 2025-06-27 Md. Zahid Hasan , Abdullah Tamim , D. M. Asadujjaman , Md. Mahfujur Rahman , Md. Abu Ahnaf Mollick , Nosin Anjum Dristi , Abdullah-Al-Noman

Physical models in the form of partial differential equations serve as important priors for many under-constrained problems. One such application is tumor treatment planning, which relies on accurately estimating the spatial distribution of…

Brains with complex distortion of cerebral anatomy present several challenges to automatic tissue segmentation methods of T1-weighted MR images. First, the very high variability in the morphology of the tissues can be incompatible with the…

Tissues and Organs · Quantitative Biology 2020-03-25 Gabriele Amorosino , Denis Peruzzo , Pietro Astolfi , Daniela Redaelli , Paolo Avesani , Filippo Arrigoni , Emanuele Olivetti

Deep learning shows high potential for many medical image analysis tasks. Neural networks can work with full-size data without extensive preprocessing and feature generation and, thus, information loss. Recent work has shown that the…

We describe a fully-automatic 3D-segmentation technique for brain MR images. Using Markov random fields the segmentation algorithm captures three important MR features, i.e. non-parametric distributions of tissue intensities, neighborhood…

Computer Vision and Pattern Recognition · Computer Science 2009-03-20 Karsten Held , Elena Rota Kops , Bernd J. Krause , William M. Wells , Ron Kikinis , Hans-Wilhelm Mueller-Gaertner

Magnetic resonance imaging (MRI) is critically important for brain mapping in both scientific research and clinical studies. Precise segmentation of brain tumors facilitates clinical diagnosis, evaluations, and surgical planning. Deep…

Image and Video Processing · Electrical Eng. & Systems 2023-05-01 Rui Nian , Guoyao Zhang , Yao Sui , Yuqi Qian , Qiuying Li , Mingzhang Zhao , Jianhui Li , Ali Gholipour , Simon K. Warfield

Medical image segmentation, the task of partitioning an image into meaningful parts, is an important step toward automating medical image analysis and is at the crux of a variety of medical imaging applications, such as computer aided…

Computer Vision and Pattern Recognition · Computer Science 2016-07-06 Masoud S. Nosrati , Ghassan Hamarneh

Recently, there have been several concerted international efforts - the BRAIN initiative, European Human Brain Project and the Human Connectome Project, to name a few - that hope to revolutionize our understanding of the connected brain.…

Neurons and Cognition · Quantitative Biology 2016-02-10 Adeel Razi , Karl Friston

Brain lesion segmentation plays an essential role in neurological research and diagnosis. As brain lesions can be caused by various pathological alterations, different types of brain lesions tend to manifest with different characteristics…

Image and Video Processing · Electrical Eng. & Systems 2024-07-17 Xinru Zhang , Ni Ou , Berke Doga Basaran , Marco Visentin , Mengyun Qiao , Renyang Gu , Cheng Ouyang , Yaou Liu , Paul M. Matthew , Chuyang Ye , Wenjia Bai

Brain tissue segmentation has demonstrated great utility in quantifying MRI data through Voxel-Based Morphometry and highlighting subtle structural changes associated with various conditions within the brain. However, manual segmentation is…

Image and Video Processing · Electrical Eng. & Systems 2023-02-02 Vishwanatha M. Rao , Zihan Wan , Soroush Arabshahi , David J. Ma , Pin-Yu Lee , Ye Tian , Xuzhe Zhang , Andrew F. Laine , Jia Guo

Brain is an organ that controls activities of all the parts of the body. Recognition of automated brain tumor in Magnetic resonance imaging (MRI) is a difficult task due to complexity of size and location variability. This automatic method…

Medical Physics · Physics 2017-06-21 Neha Rani , Sharda Vashisth