Related papers: An Ultrasonically Actuated Fine-Needle Creates Cav…
Non-invasive therapeutic ultrasound methods, such as high-intensity focused ultrasound (HIFU), have limited access to tissue targets shadowed by bones or presence of gas. This study demonstrates that an ultrasonically actuated medical…
Ultrasonic cavitation is the formation of vapour cavities within a liquid due to the action of an ultrasound source. It is widely used for homogenization, dispersion, deagglomeration, erosion, cleaning, milling, emulsification, extraction,…
This work investigates the fundamental role of cavitation bubble clouds in stone comminution by focused ultrasound. The fragmentation of stones by ultrasound has applications in medical lithotripsy for the comminution of kidney stones or…
Despite the ubiquitous use over the past 150 years, the functions of the current medical needle are facilitated only by mechanical shear and cutting by the needle tip,i.e.the lancet. In this study, we demonstrate how nonlinear ultrasonics…
Cavitation has historically been related to parameters measured at equilibrium, such as vapor pressure and surface tension. However, nucleation might occur when the liquid is metastable, especially for fast phenomena such as cavitation…
While the ultrasound and cavitation based therapies have mushroomed over the years, there is a lack of online monitoring the cavitation bubble dynamics in biological tissue. {\color{black}Here we demonstrate that with ultrasonic plane wave…
Ultrasonic irradiation of liquids, such as water-alcohol solutions, results in cavitation or the formation of small bubbles. Cavitation bubbles are generated in real solutions without the use of optical traps making our system as close to…
Focused ultrasound stimulated microbubbles have been shown to be capable of inducing blood flow shutdown and necrosis in a range of tissue types in an approach termed antivascular ultrasound or mechanical ablation. In oncology, this…
A large-scale molecular dynamics (MD) simulation of acoustic cavitation in a simple liquid was performed using the supercomputer Fugaku. The system, consisting of approximately 100 billion atoms, was subjected to ultrasonic irradiation.…
Ultrasound is a well-established method for particle size reduction in dispersions and emulsions. Ultrasonic processors are used in the generation of nano-size material slurries, dispersions and emulsions because of the potential in the…
In this fluid dynamics video we show acoustic cavitation occurring from pits etched on a silicon surface. By immersing the surface in a liquid, gas pockets are entrapped in the pits which upon ultrasonic insonation, are observed to shed…
Localized cavitation in liquids and soft tissues, typically initiated by the rarefaction phase of high-amplitude ultrasound waves, is leveraged in several biomedical applications such as ablation techniques and drug delivery with vaporizing…
Stiff and dense fibrin networks in chronic blood clots impede drug penetration and distribution into the clot core, limiting the efficacy of thrombolytic therapies. Acoustic cavitation of microbubbles is a promising strategy to enhance drug…
To further understand their nature, micro cavitation bubbles were systematically diffused around the exterior of a test body (tube) fully submerged in a water tank. The primary purpose was to assess the feasibility of applying micro…
Mesoporous silica nanoparticles have been reported as suitable drug carriers, but their successful delivery to target tissues following systemic administration remains a challenge. In the present work, ultrasound-induced inertial cavitation…
Ultrasound-induced degradation of soft polymeric colloids, like microgels, as well as a controlled drug release enabled by mechanoresponsive bonds, has recently attracted considerable attention. However, most examples in the literature…
The dynamics of cavitation bubbles in the vicinity of a solid cylinder or fibre are seen in water treatment, demolition and/or cleaning of composite materials, as well as bio-medical scenarios such as ultrasound-induced bubbles near the…
Despite its relevance in biology and engineering, the molecular mechanism driving cavitation in water remains unknown. Using computer simulations, we investigate the structure and dynamics of vapor bubbles emerging from metastable water at…
High-intensity ultrasound excites pre-existing bubbles in tissue-like material, and the subsequent bubble activity may lead to damage. To investigate such damage mechanisms, agar tissue-mimicking phantoms were subjected to multiple pressure…
The ability to precisely trap, transport and manipulate micrometer-sized objects, including biological cells, DNA-coated microspheres and microorganisms, is very important in life science studies and biomedical applications. In this study,…