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Variational autoencoders (VAE) are a powerful and widely-used class of models to learn complex data distributions in an unsupervised fashion. One important limitation of VAEs is the prior assumption that latent sample representations are…

Machine Learning · Computer Science 2018-11-27 Francesco Paolo Casale , Adrian V Dalca , Luca Saglietti , Jennifer Listgarten , Nicolo Fusi

Large Language Model (LLM)-based scientific agents have accelerated scientific discovery, yet they often suffer from significant inefficiencies due to adherence to fixed initial priors. Existing approaches predominantly operate within a…

Machine Learning · Computer Science 2026-02-09 Yingming Pu , Tao Lin , Hongyu Chen

Latent Gaussian models (LGMs) are a popular class of Bayesian hierarchical models that include Gaussian processes, as well as certain spatial models and mixed-effect models. Efficient Bayesian inference of LGMs often requires marginalizing…

Machine Learning · Statistics 2026-05-21 Jinlin Lai , Charles C. Margossian , Daniel R. Sheldon

The future predictive performance of a Bayesian model can be estimated using Bayesian cross-validation. In this article, we consider Gaussian latent variable models where the integration over the latent values is approximated using the…

Computation · Statistics 2016-08-09 Aki Vehtari , Tommi Mononen , Ville Tolvanen , Tuomas Sivula , Ole Winther

Max-stable processes are the most popular models for high-impact spatial extreme events, as they arise as the only possible limits of spatially-indexed block maxima. However, likelihood inference for such models suffers severely from the…

Methodology · Statistics 2022-03-14 Raphaël Huser , Michael L. Stein , Peng Zhong

A new empirical Bayes approach to variable selection in the context of generalized linear models is developed. The proposed algorithm scales to situations in which the number of putative explanatory variables is very large, possibly much…

Methodology · Statistics 2021-06-29 Haim Bar , James Booth , Martin T. Wells

Understanding cause-specific mortality rates is crucial for monitoring population health and designing public health interventions. Worldwide, two-thirds of deaths do not have a cause assigned. Verbal autopsy (VA) is a well-established tool…

Methodology · Statistics 2023-06-26 Zehang Richard Li , Zhenke Wu , Irena Chen , Samuel J. Clark

Predicting future frames for a video sequence is a challenging generative modeling task. Promising approaches include probabilistic latent variable models such as the Variational Auto-Encoder. While VAEs can handle uncertainty and model…

Computer Vision and Pattern Recognition · Computer Science 2019-04-30 Lluis Castrejon , Nicolas Ballas , Aaron Courville

We propose a random-effects approach to missing values for generalized linear mixed model (GLMM) analysis. The method converts a GLMM with missing covariates to another GLMM without missing covariates. The standard GLMM analysis tools for…

Methodology · Statistics 2026-01-01 Thuan Nguyen , Jiangshan Zhang , Jiming Jiang

Deep generative models like VAEs and diffusion models have advanced various generation tasks by leveraging latent variables to learn data distributions and generate high-quality samples. Despite the field of explainable AI making strides in…

Machine Learning · Computer Science 2025-12-22 Mengdan Zhu , Raasikh Kanjiani , Jiahui Lu , Andrew Choi , Qirui Ye , Liang Zhao

Generalized linear mixed models (GLMMs) are used to model responses from exponential families with a combination of fixed and random effects. For variance components in GLMMs, we propose an approximate restricted likelihood ratio test that…

Methodology · Statistics 2019-06-11 Stephanie T. Chen , Luo Xiao , Ana-Maria Staicu

Generalized linear models (GLMs) -- such as logistic regression, Poisson regression, and robust regression -- provide interpretable models for diverse data types. Probabilistic approaches, particularly Bayesian ones, allow coherent…

Computation · Statistics 2018-12-19 Jonathan H. Huggins , Ryan P. Adams , Tamara Broderick

Large pre-trained vision-language models (VLMs) offer a promising approach to leveraging human language for enhancing downstream tasks. However, VLMs such as CLIP face significant limitation: its performance is highly sensitive to prompt…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Ao Li , Zongfang Liu , Xinhua Li , Jinghui Zhang , Pengwei Wang , Hu Wang

Randomized neural networks (NNs) are an interesting alternative to conventional NNs that are more used for data modeling. The random vector functional-link (RVFL) network is an established and theoretically well-grounded randomized learning…

Computation · Statistics 2018-04-24 Hien D. Nguyen , Dianhui Wang , Geoffrey J. McLachlan

We would like to learn a representation of the data which decomposes an observation into factors of variation which we can independently control. Specifically, we want to use minimal supervision to learn a latent representation that…

Machine Learning · Computer Science 2017-05-25 Diane Bouchacourt , Ryota Tomioka , Sebastian Nowozin

Multivariate time series with missing values are common in areas such as healthcare and finance, and have grown in number and complexity over the years. This raises the question whether deep learning methodologies can outperform classical…

Machine Learning · Statistics 2020-02-21 Vincent Fortuin , Dmitry Baranchuk , Gunnar Rätsch , Stephan Mandt

We propose DoE2Vec, a variational autoencoder (VAE)-based methodology to learn optimization landscape characteristics for downstream meta-learning tasks, e.g., automated selection of optimization algorithms. Principally, using large…

Optimization and Control · Mathematics 2023-04-05 Bas van Stein , Fu Xing Long , Moritz Frenzel , Peter Krause , Markus Gitterle , Thomas Bäck

The univariate generalized extreme value (GEV) distribution is the most commonly used tool for analyzing the properties of rare events. The ever greater utilization of Bayesian methods for extreme value analysis warrants detailed…

Statistics Theory · Mathematics 2023-07-03 Likun Zhang , Benjamin A. Shaby

An ordinary differential equation (ODE) model, whose regression curves are a set of solution curves for some ODEs, poses a challenge in parameter estimation. The challenge, due to the frequent absence of analytic solutions and the…

Computation · Statistics 2021-08-11 Hyunjoo Yang , Jaeyong Lee

The Laplace approximation has been one of the workhorses of Bayesian inference. It often delivers good approximations in practice despite the fact that it does not strictly take into account where the volume of posterior density lies.…

Machine Learning · Statistics 2022-03-02 Nikolaos Gianniotis