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In medical imaging, outliers can contain hypo/hyper-intensities, minor deformations, or completely altered anatomy. To detect these irregularities it is helpful to learn the features present in both normal and abnormal images. However this…

Computer Vision and Pattern Recognition · Computer Science 2024-03-15 Jeremy Tan , Benjamin Hou , James Batten , Huaqi Qiu , Bernhard Kainz

Although neural networks have proven very successful in a number of medical image analysis applications, their use remains difficult when targeting subtle tasks such as the identification of barely visible brain lesions, especially given…

Image and Video Processing · Electrical Eng. & Systems 2021-10-26 Verónica Muñoz-Ramírez , Nicolas Pinon , Florence Forbes , Carole Lartizen , Michel Dojat

Anomaly detection methods generally target the learning of a normal image distribution (i.e., inliers showing healthy cases) and during testing, samples relatively far from the learned distribution are classified as anomalies (i.e.,…

Computer Vision and Pattern Recognition · Computer Science 2020-06-29 Yu Tian , Gabriel Maicas , Leonardo Zorron Cheng Tao Pu , Rajvinder Singh , Johan W. Verjans , Gustavo Carneiro

Anomaly detection is the problem of recognizing abnormal inputs based on the seen examples of normal data. Despite recent advances of deep learning in recognizing image anomalies, these methods still prove incapable of handling complex…

Computer Vision and Pattern Recognition · Computer Science 2021-09-14 Nina Shvetsova , Bart Bakker , Irina Fedulova , Heinrich Schulz , Dmitry V. Dylov

Manifold models consider natural-image patches to be on a low-dimensional manifold embedded in a high dimensional state space and each patch and its similar patches to approximately lie on a linear affine subspace. Manifold models are…

Computer Vision and Pattern Recognition · Computer Science 2021-08-03 Lantao Yu , Kuida Liu , Michael T. Orchard

Anomaly detection in medical images refers to the identification of abnormal images with only normal images in the training set. Most existing methods solve this problem with a self-reconstruction framework, which tends to learn an identity…

Image and Video Processing · Electrical Eng. & Systems 2021-10-06 Kang Zhou , Jing Li , Weixin Luo , Zhengxin Li , Jianlong Yang , Huazhu Fu , Jun Cheng , Jiang Liu , Shenghua Gao

Due to the high cost of manually annotating medical images, especially for large-scale datasets, anomaly detection has been explored through training models with only normal data. Lacking prior knowledge of true anomalies is the main reason…

Image and Video Processing · Electrical Eng. & Systems 2022-03-15 Weikai Huang , Yijin Huang , Xiaoying Tang

Anomaly detection and localization in medical images is a challenging task, especially when the anomaly exhibits a change of existing structures, e.g., brain atrophy or changes in the pleural space due to pleural effusions. In this work, we…

Image and Video Processing · Electrical Eng. & Systems 2020-07-29 Julia Wolleb , Robin Sandkühler , Philippe C. Cattin

Detection of various lesions in brain MRI is clinically critical, but challenging due to the diversity of lesions and variability in imaging conditions. Current unsupervised learning methods detect anomalies mainly through reconstructing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Tao Yang , Xiuying Wang , Hao Liu , Guanzhong Gong , Lian-Ming Wu , Yu-Ping Wang , Lisheng Wang

Anomaly detection in medical imaging is a challenging task in contexts where abnormalities are not annotated. This problem can be addressed through unsupervised anomaly detection (UAD) methods, which identify features that do not match with…

Image and Video Processing · Electrical Eng. & Systems 2023-09-07 Geoffroy Oudoumanessah , Carole Lartizien , Michel Dojat , Florence Forbes

Image anomaly detection consists in detecting images or image portions that are visually different from the majority of the samples in a dataset. The task is of practical importance for various real-life applications like biomedical image…

Computer Vision and Pattern Recognition · Computer Science 2022-10-28 Axel De Nardin , Pankaj Mishra , Gian Luca Foresti , Claudio Piciarelli

The use of supervised deep learning techniques to detect pathologies in brain MRI scans can be challenging due to the diversity of brain anatomy and the need for annotated data sets. An alternative approach is to use unsupervised anomaly…

Image and Video Processing · Electrical Eng. & Systems 2023-03-08 Finn Behrendt , Debayan Bhattacharya , Julia Krüger , Roland Opfer , Alexander Schlaefer

We present a novel method for image anomaly detection, where algorithms that use samples drawn from some distribution of "normal" data, aim to detect out-of-distribution (abnormal) samples. Our approach includes a combination of encoder and…

Image and Video Processing · Electrical Eng. & Systems 2020-03-02 Nina Tuluptceva , Bart Bakker , Irina Fedulova , Anton Konushin

Because anomalous samples cannot be used for training, many anomaly detection and localization methods use pre-trained networks and non-parametric modeling to estimate encoded feature distribution. However, these methods neglect the impact…

Computer Vision and Pattern Recognition · Computer Science 2023-03-31 Jaehyeok Bae , Jae-Han Lee , Seyun Kim

The increasing digitization of medical imaging enables machine learning based improvements in detecting, visualizing and segmenting lesions, easing the workload for medical experts. However, supervised machine learning requires reliable…

Image and Video Processing · Electrical Eng. & Systems 2024-12-03 Maximilian E. Tschuchnig , Michael Gadermayr

We propose a novel unsupervised out-of-distribution detection method for medical images based on implicit fields image representations. In our approach, an auto-decoder feed-forward neural network learns the distribution of healthy images…

Image and Video Processing · Electrical Eng. & Systems 2021-06-10 Sergio Naval Marimont , Giacomo Tarroni

The scarcity of pixel-level annotation is a prevalent problem in medical image segmentation tasks. In this paper, we introduce a novel regularization strategy involving interpolation-based mixing for semi-supervised medical image…

Image and Video Processing · Electrical Eng. & Systems 2022-02-04 Hritam Basak , Rajarshi Bhattacharya , Rukhshanda Hussain , Agniv Chatterjee

Anomaly detection (AD) aims at detecting abnormal samples that deviate from the expected normal patterns. Generally, it can be trained merely on normal data, without a requirement for abnormal samples, and thereby plays an important role in…

Computer Vision and Pattern Recognition · Computer Science 2025-02-20 Yu Cai , Weiwen Zhang , Hao Chen , Kwang-Ting Cheng

Distance-based anomaly detection methods rely on compact in-distribution (ID) embeddings that are well separated from anomalies. However, conventional contrastive learning strategies often struggle to achieve this balance, either promoting…

Machine Learning · Computer Science 2026-02-02 Willian T. Lunardi , Abdulrahman Banabila , Dania Herzalla , Martin Andreoni

In recent years, anomaly detection has become an essential field in medical image analysis. Most current anomaly detection methods for medical images are based on image reconstruction. In this work, we propose a novel anomaly detection…

Computer Vision and Pattern Recognition · Computer Science 2023-01-20 Florentin Bieder , Julia Wolleb , Robin Sandkühler , Philippe C. Cattin
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