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Medical image synthesis remains challenging due to misalignment noise during training. Existing methods have attempted to address this challenge by incorporating a registration-guided module. However, these methods tend to overlook the…

Computer Vision and Pattern Recognition · Computer Science 2024-07-11 Chuanpu Li , Zeli Chen , Yiwen Zhang , Liming Zhong , Wei Yang

Regularization is a fundamental technique to prevent over-fitting and to improve generalization performances by constraining a model's complexity. Current Deep Networks heavily rely on regularizers such as Data-Augmentation (DA) or…

Machine Learning · Computer Science 2022-04-12 Randall Balestriero , Leon Bottou , Yann LeCun

Batch normalization (BN) is a ubiquitous technique for training deep neural networks that accelerates their convergence to reach higher accuracy. However, we demonstrate that BN comes with a fundamental drawback: it incentivizes the model…

Machine Learning · Computer Science 2022-07-05 Saeid Asgari Taghanaki , Ali Gholami , Fereshte Khani , Kristy Choi , Linh Tran , Ran Zhang , Aliasghar Khani

Image registration is an inherently ill-posed problem that lacks the constraints needed for a unique mapping between voxels of the two images being registered. As such, one must regularize the registration to achieve physically meaningful…

Numerical Analysis · Mathematics 2025-02-03 Keyur D. Shah , James A. Shackleford , Nagarajan Kandasamy , Gregory C. Sharp

Presently the most successful approaches to semi-supervised learning are based on consistency regularization, whereby a model is trained to be robust to small perturbations of its inputs and parameters. To understand consistency…

Machine Learning · Computer Science 2019-02-22 Ben Athiwaratkun , Marc Finzi , Pavel Izmailov , Andrew Gordon Wilson

Regularization, whether explicit in terms of a penalty in the loss or implicit in the choice of algorithm, is a cornerstone of modern machine learning. Indeed, controlling the complexity of the model class is particularly important when…

Machine Learning · Statistics 2024-10-22 Matteo Vilucchio , Nikolaos Tsilivis , Bruno Loureiro , Julia Kempe

Adversarial training (AT) has proven to be one of the most effective ways to defend Deep Neural Networks (DNNs) against adversarial attacks. However, the phenomenon of robust overfitting, i.e., the robustness will drop sharply at a certain…

Machine Learning · Computer Science 2022-05-25 Shudong Zhang , Haichang Gao , Tianwei Zhang , Yunyi Zhou , Zihui Wu

Data augmentation has been proven to be an effective technique for developing machine learning models that are robust to known classes of distributional shifts (e.g., rotations of images), and alignment regularization is a technique often…

Machine Learning · Computer Science 2022-06-07 Haohan Wang , Zeyi Huang , Xindi Wu , Eric P. Xing

It's well-known that inverse problems are ill-posed and to solve them meaningfully one has to employ regularization methods. Traditionally, popular regularization methods have been the penalized Variational approaches. In recent years, the…

Machine Learning · Computer Science 2022-02-17 Abinash Nayak

Training materials through periodic drive allows to endow materials and structures with complex elastic functions. As a result of the driving, the system explores the high dimensional space of structures, ultimately converging to a…

Soft Condensed Matter · Physics 2023-08-10 Himangsu Bhaumik , Daniel Hexner

In representation learning (RL), how to make the learned representations easy to interpret and less overfitted to training data are two important but challenging issues. To address these problems, we study a new type of regulariza- tion…

Machine Learning · Computer Science 2017-11-28 Pengtao Xie , Hongbao Zhang , Eric P. Xing

Deep learning methods for unsupervised registration often rely on objectives that assume a uniform noise level across the spatial domain (e.g. mean-squared error loss), but noise distributions are often heteroscedastic and input-dependent…

Image and Video Processing · Electrical Eng. & Systems 2024-07-19 Xiaoran Zhang , Daniel H. Pak , Shawn S. Ahn , Xiaoxiao Li , Chenyu You , Lawrence H. Staib , Albert J. Sinusas , Alex Wong , James S. Duncan

Reinforcement learning (RL) is recognized as lacking generalization and robustness under environmental perturbations, which excessively restricts its application for real-world robotics. Prior work claimed that adding regularization to the…

Machine Learning · Computer Science 2023-12-06 Yuan Zhang , Jianhong Wang , Joschka Boedecker

The effectiveness of neural network models largely relies on learning meaningful latent patterns from data, where self-supervised learning of informative representations can enhance model performance and generalisability. However,…

Machine Learning · Computer Science 2025-10-28 Yiru Jiao , Sander van Cranenburgh , Simeon Calvert , Hans van Lint

Regularization techniques are widely employed in optimization-based approaches for solving ill-posed inverse problems in data analysis and scientific computing. These methods are based on augmenting the objective with a penalty function,…

Optimization and Control · Mathematics 2021-06-08 Yong Sheng Soh , Venkat Chandrasekaran

Image registration is a key technique in medical image analysis to estimate deformations between image pairs. A good deformation model is important for high-quality estimates. However, most existing approaches use ad-hoc deformation models…

Computer Vision and Pattern Recognition · Computer Science 2019-04-23 Marc Niethammer , Roland Kwitt , Francois-Xavier Vialard

The successful training of deep neural networks requires addressing challenges such as overfitting, numerical instabilities leading to divergence, and increasing variance in the residual stream. A common solution is to apply regularization…

Machine Learning · Computer Science 2025-11-20 Jörg K. H. Franke , Urs Spiegelhalter , Marianna Nezhurina , Jenia Jitsev , Frank Hutter , Michael Hefenbrock

Low-complexity non-smooth convex regularizers are routinely used to impose some structure (such as sparsity or low-rank) on the coefficients for linear predictors in supervised learning. Model consistency consists then in selecting the…

Optimization and Control · Mathematics 2019-01-17 Jalal Fadili , Guillaume Garrigos , Jérome Malick , Gabriel Peyré

This study presents the development of a spatially adaptive weighting strategy for Total Variation regularization, aimed at addressing under-determined linear inverse problems. The method leverages the rapid computation of an accurate…

Numerical Analysis · Mathematics 2025-01-20 Elena Morotti , Davide Evangelista , Andrea Sebastiani , Elena Loli Piccolomini

Uncertainty quantification is vital for decision-making and risk assessment in machine learning. Mean-variance regression models, which predict both a mean and residual noise for each data point, provide a simple approach to uncertainty…

Machine Learning · Statistics 2025-12-01 Eliot Wong-Toi , Alex Boyd , Vincent Fortuin , Stephan Mandt