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Introduction: Artificial intelligence (AI) is exhibiting tremendous potential to reduce the massive costs and long timescales of drug discovery. There are however important challenges currently limiting the impact and scope of AI models.…
This study explores the integration of contextual explanations into AI-powered loan decision systems to enhance trust and usability. While traditional AI systems rely heavily on algorithmic transparency and technical accuracy, they often…
While context compression can mitigate the growing inference costs of Large Language Models (LLMs) by shortening contexts, existing methods that specify a target compression ratio or length suffer from unpredictable performance degradation,…
The increasing deployment of artificial intelligence (AI) in clinical settings challenges foundational assumptions underlying traditional frameworks of medical evidence. Classical statistical approaches, centered on randomized controlled…
Explainability is key to enhancing artificial intelligence's trustworthiness in medicine. However, several issues remain concerning the actual benefit of explainable models for clinical decision-making. Firstly, there is a lack of consensus…
The significant advances in autonomous systems together with an immensely wider application domain have increased the need for trustable intelligent systems. Explainable artificial intelligence is gaining considerable attention among…
Many clinical deep learning algorithms are population-based and difficult to interpret. Such properties limit their clinical utility as population-based findings may not generalize to individual patients and physicians are reluctant to…
Disease prediction holds considerable significance in modern healthcare, because of its crucial role in facilitating early intervention and implementing effective prevention measures. However, most recent disease prediction approaches…
With the increasing use of generative Artificial Intelligence (AI) methods to support science workflows, we are interested in the use of discourse-level information to find supporting evidence for AI generated scientific claims. A first…
The use of machine learning and AI on electronic health records (EHRs) holds substantial potential for clinical insight. However, this approach faces challenges due to data heterogeneity, sparsity, temporal misalignment, and limited labeled…
This study investigated the performance, explainability, and robustness of deployed artificial intelligence (AI) models in predicting mortality during the COVID-19 pandemic and beyond. The first study of its kind, we found that Bayesian…
Clinical reasoning refers to the cognitive process that physicians employ in evaluating and managing patients. This process typically involves suggesting necessary examinations, diagnosing patients' diseases, and deciding on appropriate…
Probabilities of causation (PoC) are valuable concepts for explainable artificial intelligence and practical decision-making. PoC are originally defined for scalar binary variables. In this paper, we extend the concept of PoC to continuous…
This paper reports a case study on how explainability requirements were elicited during the development of an AI system for predicting cerebral palsy (CP) risk in infants. Over 18 months, we followed a development team and hospital…
The recent enthusiasm for artificial intelligence (AI) is due principally to advances in deep learning. Deep learning methods are remarkably accurate, but also opaque, which limits their potential use in safety-critical applications. To…
Artificial intelligence (AI) will pave the way to a new era in medicine. However, currently available AI systems do not interact with a patient, e.g., for anamnesis, and thus are only used by the physicians for predictions in diagnosis or…
AI systems have been widely adopted across various domains in the real world. However, in high-value, sensitive, or safety-critical applications such as self-management for personalized health or food recommendation with a specific purpose…
Predictive modelling is important for health data analysis and data-driven clinical decision-making. However, predictive studies are challenging to design optimally by hand when tens or even hundreds of features require selection,…
In medical imaging, particularly in early disease detection and prognosis tasks, discerning the rationale behind an AI model's predictions is crucial for evaluating the reliability of its decisions. Conventional explanation methods face…
Explainable Artificial Intelligence (AI) focuses on helping humans understand the working of AI systems or their decisions and has been a cornerstone of AI for decades. Recent research in explainability has focused on explaining the…