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We perform a finite sample analysis of the detection levels for sparse principal components of a high-dimensional covariance matrix. Our minimax optimal test is based on a sparse eigenvalue statistic. Alas, computing this test is known to…

Statistics Theory · Mathematics 2014-01-30 Quentin Berthet , Philippe Rigollet

Given a sample covariance matrix, we examine the problem of maximizing the variance explained by a linear combination of the input variables while constraining the number of nonzero coefficients in this combination. This is known as sparse…

Artificial Intelligence · Computer Science 2011-11-10 Alexandre d'Aspremont , Francis Bach , Laurent El Ghaoui

Selecting the most relevant features and samples out of a large set of candidates is a task that occurs very often in the context of automated data analysis, where it can be used to improve the computational performance, and also often the…

Chemical Physics · Physics 2020-12-23 Rose K. Cersonsky , Benjamin A. Helfrecht , Edgar A. Engel , Michele Ceriotti

We introduce a statistical physics inspired supervised machine learning algorithm for classification and regression problems. The method is based on the invariances or stability of predicted results when known data is represented as…

Machine Learning · Statistics 2018-11-19 Patrick Chao , Tahereh Mazaheri , Bo Sun , Nicholas B. Weingartner , Zohar Nussinov

An important problem in the analysis of high-dimensional omics data is to identify subsets of molecular variables that are associated with a phenotype of interest. This requires addressing the challenges of high dimensionality, strong…

Methodology · Statistics 2022-04-05 Fan Wang , Sylvia Richardson , Steven M. Hill

Sparse coding (SC) is attracting more and more attention due to its comprehensive theoretical studies and its excellent performance in many signal processing applications. However, most existing sparse coding algorithms are nonconvex and…

Machine Learning · Computer Science 2017-09-12 Xiaodong Feng , Zhiwei Tang , Sen Wu

Machine learning and statistics typically focus on building models that capture the vast majority of the data, possibly ignoring a small subset of data as "noise" or "outliers." By contrast, here we consider the problem of jointly…

Machine Learning · Computer Science 2016-08-19 Brendan Juba

Sparse principal component analysis (PCA) is an important technique for dimensionality reduction of high-dimensional data. However, most existing sparse PCA algorithms are based on non-convex optimization, which provide little guarantee on…

Methodology · Statistics 2019-11-20 Yixuan Qiu , Jing Lei , Kathryn Roeder

The performance of machine learning and pattern recognition algorithms generally depends on data representation. That is why, much of the current effort in performing machine learning algorithms goes into the design of preprocessing…

Machine Learning · Computer Science 2025-10-28 Fadi Dornaika , Ahmad Khoder , Abdelmalik Moujahid , Wassim Khoder

The sparse linear regression problem is difficult to handle with usual sparse optimization models when both predictors and measurements are either quantized or represented in low-precision, due to non-convexity. In this paper, we provide a…

Optimization and Control · Mathematics 2019-03-22 Vito Cerone , Sophie M. Fosson , Diego Regruto

Spatially resolved transcriptomics is a fast-developing set of technologies that enables the measurement of localized gene expression across spatial locations in a sample. Detecting spatially varying genes is critical for analyzing such…

Applications · Statistics 2026-04-22 Pritam Dey , Rajarshi Guhaniyogi , Yang Ni , Bani K. Mallick

Functional principal component analysis (FPCA) is a key tool in the study of functional data, driving both exploratory analyses and feature construction for use in formal modeling and testing procedures. However, existing methods for FPCA…

Methodology · Statistics 2026-03-24 Caitrin Murphy , Eric Laber , Rhonda Merwin , Brian Reich , Jake Koerner

Principal components analysis (PCA) is a classical method for the reduction of dimensionality of data in the form of n observations (or cases) of a vector with p variables. For a simple model of factor analysis type, it is proved that…

Statistics Theory · Mathematics 2009-01-29 Iain M Johnstone , Arthur Yu Lu

We examine the problem of selecting a small set of linear measurements for reconstructing high-dimensional signals. Well-established methods for optimizing such measurements include principal component analysis (PCA), independent component…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Ling-Qi Zhang , Zahra Kadkhodaie , Eero P. Simoncelli , David H. Brainard

The discovery of disease subtypes is an essential step for developing precision medicine, and disease subtyping via omics data has become a popular approach. While promising, subtypes obtained from existing approaches are not necessarily…

Quantitative Methods · Quantitative Biology 2022-03-01 Lingsong Meng , Dorina Avram , George Tseng , Zhiguang Huo

In machine learning practice it is often useful to identify relevant input features. Isolating key input elements, ranked according their respective degree of relevance, can help to elaborate on the process of decision making. Here, we…

Machine Learning · Computer Science 2025-11-24 Lorenzo Chicchi , Lorenzo Buffoni , Diego Febbe , Lorenzo Giambagli , Raffaele Marino , Duccio Fanelli

Deep neural networks have emerged as powerful tools for learning operators defined over infinite-dimensional function spaces. However, existing theories frequently encounter difficulties related to dimensionality and limited…

Machine Learning · Computer Science 2026-05-12 Jianfei Li , Shuo Huang , Han Feng , Ding-Xuan Zhou , Gitta Kutyniok

Sparse additive modeling is a class of effective methods for performing high-dimensional nonparametric regression. In this work we show how shape constraints such as convexity/concavity and their extensions, can be integrated into additive…

Machine Learning · Computer Science 2017-05-03 Junming Yin , Yaoliang Yu

This paper studies the sparse identification problem of unknown sparse parameter vectors in stochastic dynamic systems. Firstly, a novel sparse identification algorithm is proposed, which can generate sparse estimates based on least squares…

Optimization and Control · Mathematics 2024-04-02 Ziming Wang , Xinghua Zhu

The computation of the sparse principal component of a matrix is equivalent to the identification of its principal submatrix with the largest maximum eigenvalue. Finding this optimal submatrix is what renders the problem…

Information Theory · Computer Science 2013-12-23 Megasthenis Asteris , Dimitris S. Papailiopoulos , George N. Karystinos
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