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Related papers: Convex optimization of bioprocesses

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This paper mainly focuses on solving the dynamic optimization of the planar controlled crowd motion models with obstacles which is an application of a class of optimal control problems governed by a general perturbed nonconvex sweeping…

Optimization and Control · Mathematics 2021-04-09 Tan Cao , Boris Mordukhovich , Dao Nguyen , Trang Nguyen

Biological systems perform complex multi-step processes in a reproducible way despite underlying stochasticity. The standard explanation is micromanagement by molecular machinery that recognizes and corrects specific errors. Here we study…

Populations and Evolution · Quantitative Biology 2026-05-14 Riccardo Ravasio , Kabir Husain , Constantine G. Evans , Rob Phillips , Marco Ribezzi-Crivellari , Jack W. Szostak , Arvind Murugan

In this paper, we introduce methods from convex optimization to solve the multimarginal transport type problems arise in the context of density functional theory. Convex relaxations are used to provide outer approximation to the set of…

Optimization and Control · Mathematics 2018-08-15 Yuehaw Khoo , Lexing Ying

We propose an accelerated meta-algorithm, which allows to obtain accelerated methods for convex unconstrained minimization in different settings. As an application of the general scheme we propose nearly optimal methods for minimizing…

Convex optimization problems arising in applications often have favorable objective functions and complicated constraints, thereby precluding first-order methods from being immediately applicable. We describe an approach that exchanges the…

Optimization and Control · Mathematics 2016-02-05 Aleksandr Y. Aravkin , James V. Burke , Dmitriy Drusvyatskiy , Michael P. Friedlander , Scott Roy

We characterize the solution of a broad class of convex optimization problems that address the reconstruction of a function from a finite number of linear measurements. The underlying hypothesis is that the solution is decomposable as a…

Optimization and Control · Mathematics 2021-07-26 Michael Unser , Shayan Aziznejad

This paper introduces several new algorithms for consensus over the special orthogonal group. By relying on a convex relaxation of the space of rotation matrices, consensus over rotation elements is reduced to solving a convex problem with…

Optimization and Control · Mathematics 2014-10-08 Nikolai Matni , Matanya B. Horowitz

Fluence map optimization for intensity-modulated radiation therapy planning can be formulated as a large-scale inverse problem with competing objectives and constraints associated with the tumors and organs-at-risk. Unfortunately,…

Optimization and Control · Mathematics 2022-02-17 Kelsey Maass , Minsun Kim , Aleksandr Aravkin

Recently, the centroidal momentum dynamics has received substantial attention to plan dynamically consistent motions for robots with arms and legs in multi-contact scenarios. However, it is also non convex which renders any optimization…

Robotics · Computer Science 2018-02-27 Brahayam Ponton , Alexander Herzog , Andrea Del Prete , Stefan Schaal , Ludovic Righetti

This paper develops a general framework for solving a variety of convex cone problems that frequently arise in signal processing, machine learning, statistics, and other fields. The approach works as follows: first, determine a conic…

Optimization and Control · Mathematics 2011-12-20 Stephen R. Becker , Emmanuel J. Candès , Michael Grant

Various biological system models have been proposed in systems biology, which are based on the complex biological reactions kinetic of various components. These models are not practical because we lack of kinetic information. In this paper,…

Quantitative Methods · Quantitative Biology 2011-02-19 Weidong Huang , Chundu Wu , Bingjia Xiao , Weidong Xia

The hydrogen production curve of the electrolyzer describes the non-linear and non-convex relationship between its power consumption and hydrogen production. An accurate representation of this curve is essential for the optimal scheduling…

Optimization and Control · Mathematics 2023-09-14 Enrica Raheli , Yannick Werner , Jalal Kazempour

Any process in which competing solutions replicate with errors and numbers of their copies depend on their respective fitnesses is the evolutionary optimization process. As during carcinogenesis mutated genomes replicate according to their…

Populations and Evolution · Quantitative Biology 2009-12-15 B. Brutovsky , D. Horvath

We discuss the relaxation kinetics of a one-dimensional dimer adsorption model as recently proposed for the binding of biological dimers like kinesin on microtubules. The non-equilibrium dynamics shows several regimes: irreversible…

Soft Condensed Matter · Physics 2007-05-23 Andrej Vilfan , Erwin Frey , Franz Schwabl

We propose a zero-order optimization method for sequential min-max problems based on two populations of interacting particles. The systems are coupled so that one population aims to solve the inner maximization problem, while the other aims…

Optimization and Control · Mathematics 2024-07-25 Giacomo Borghi , Hui Huang , Jinniao Qiu

We present a model for continuous cell culture coupling intra-cellular metabolism to extracellular variables describing the state of the bioreactor, taking into account the growth capacity of the cell and the impact of toxic byproduct…

Molecular Networks · Quantitative Biology 2017-11-21 Jorge Fernandez-de-Cossio-Diaz , Kalet León , Roberto Mulet

We propose a kinetic relaxation-model to describe a generation-recombination reaction of two species. The decay to equilibrium is studied by two recent methods for proving hypocoercivity of the linearized equations. Exponential decay of…

Analysis of PDEs · Mathematics 2015-03-20 Lukas Neumann , Christian Schmeiser

Variations of physical and chemical characteristics of biomass lead to an uneven flow of biomass in a biorefinery, which reduces equipment utilization and increases operational costs. Uncertainty of biomass supply and high processing costs…

Optimization and Control · Mathematics 2021-01-11 Berkay Gulcan , Sandra D. Eksioglu , Yongjia Song , Mohammad Roni , Qiushi Chen

A general class of nonconvex optimization problems is considered, where the penalty is the composition of a linear operator with a nonsmooth nonconvex mapping, which is concave on the positive real line. The necessary optimality condition…

Optimization and Control · Mathematics 2018-04-23 Daria Ghilli , Karl Kunisch

Robust Markov decision processes (MDPs) are used for applications of dynamic optimization in uncertain environments and have been studied extensively. Many of the main properties and algorithms of MDPs, such as value iteration and policy…

Optimization and Control · Mathematics 2023-12-14 Julien Grand-Clément , Marek Petrik