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Distinct from closed quantum systems, non-Hermitian system can have exceptional points (EPs) where both eigenvalues and eigenvectors coalesce. Recently, it has been proposed and demonstrated that EPs can enhance the performance of sensors…

Quantum Physics · Physics 2019-11-05 Mengzhen Zhang , William Sweeney , Chia Wei Hsu , Lan Yang , A. D. Stone , Liang Jiang

Single particle cryogenic electron microscopy (cryo-EM) is an imaging technique capable of recovering the high-resolution 3-D structure of biological macromolecules from many noisy and randomly oriented projection images. One notable…

Biomolecules · Quantitative Biology 2024-01-30 Andy Zhang , Oscar Mickelin , Joe Kileel , Eric J. Verbeke , Nicholas F. Marshall , Marc Aurèle Gilles , Amit Singer

In the present work, we investigate the computational efficiency afforded by higher-order finite-element discretization of the saddle-point formulation of orbital-free density functional theory. We first investigate the robustness of viable…

Computational Physics · Physics 2015-05-30 Phani Motamarri , Mrinal Iyer , Jaroslaw Knap , Vikram Gavini

The three-dimensional structure of proteins plays a crucial role in determining their function. Protein structure prediction methods, like AlphaFold, offer rapid access to a protein structure. However, large protein complexes cannot be…

Biomolecules · Quantitative Biology 2025-03-05 Gabriel Ducrocq , Lukas Grunewald , Sebastian Westenhoff , Fredrik Lindsten

Gravitational waves from core-collapse supernovae offer a unique probe of the equation of state (EOS) of dense nuclear matter. For rapidly rotating stars, previous machine-learning studies demonstrated promising EOS classification accuracy.…

The route to reliable quantum nanoelectronic devices hinges on precise control of the electrostatic environment. For this reason, accurate methods for electrostatic simulations are essential in the design process. The most widespread…

Mesoscale and Nanoscale Physics · Physics 2023-02-28 Waldemar Svejstrup , Andrea Maiani , Kevin Van Hoogdalem , Karsten Flensberg

Single-particle cryo-electron microscopy (cryo-EM) has become one of the mainstream structural biology techniques because of its ability to determine high-resolution structures of dynamic bio-molecules. However, cryo-EM data acquisition…

Machine Learning · Computer Science 2022-04-18 Quanfu Fan , Yilai Li , Yuguang Yao , John Cohn , Sijia Liu , Seychelle M. Vos , Michael A. Cianfrocco

We compute the distribution of the partition functions for a class of one-dimensional Random Energy Models (REM) with logarithmically correlated random potential, above and at the glass transition temperature. The random potential sequences…

Disordered Systems and Neural Networks · Physics 2010-01-18 Yan V Fyodorov , Pierre Le Doussal , Alberto Rosso

Holographic MIMO (HMIMO) is being increasingly recognized as a key enabling technology for 6G wireless systems through the deployment of an extremely large number of antennas within a compact space to fully exploit the potentials of the…

Signal Processing · Electrical Eng. & Systems 2024-06-18 Wentao Yu , Hengtao He , Xianghao Yu , Shenghui Song , Jun Zhang , Ross Murch , Khaled B. Letaief

First-order methods for stochastic optimization have undeniable relevance, in part due to their pivotal role in machine learning. Variance reduction for these algorithms has become an important research topic. In contrast to common…

Machine Learning · Computer Science 2021-09-08 Manuel Madeira , Renato Negrinho , João Xavier , Pedro M. Q. Aguiar

We propose a new method for feature learning and function estimation in supervised learning via regularised empirical risk minimisation. Our approach considers functions as expectations of Sobolev functions over all possible one-dimensional…

Machine Learning · Statistics 2025-05-01 Bertille Follain , Francis Bach

Coherent ensembles of $N$ qubits present an advantage in quantum phase estimation over separable mixtures, but coherence decay due to classical phase diffusion reduces overall precision. In some contexts, the strength of diffusion may be…

Quantum Physics · Physics 2013-07-02 Sergey I. Knysh , Gabriel A. Durkin

Motivated by the need for efficient estimation of conditional expectations, we consider a least-squares function approximation problem with heavily polluted data. Existing methods that are effective in the small-noise regime are suboptimal…

Machine Learning · Statistics 2026-05-26 Ben Adcock , Bernhard Hientzsch , Akil Narayan , Yiming Xu

This study explores the performance of the random Gaussian smoothing Zeroth-Order ExtraGradient (ZO-EG) scheme considering \Af{deterministic} min-max optimisation problems with possibly NonConvex-NonConcave (NC-NC) objective functions. We…

Optimization and Control · Mathematics 2025-09-30 Amir Ali Farzin , Yuen Man Pun , Philipp Braun , Antoine Lesage-landry , Youssef Diouane , Iman Shames

It is well known that a suggestive connection links Schr\"odinger's equation (SE) and the information-optimizing principle based on Fisher's information measure (FIM). It has been shown that this entails the existence of a Legendre…

Quantum Physics · Physics 2015-05-28 S. P. Flego , A. Plastino , A. R. Plastino

Low-energy electron microscopy (LEEM) taken as intensity-voltage (I-V) curves provides hyperspectral images of surfaces, which can be used to identify the surface type, but are difficult to analyze. Here, we demonstrate the use of an…

Materials Science · Physics 2023-03-30 Francesco Masia , Wolfgang Langbein , Simon Fischer , Jon-Olaf Krisponeit , Jens Falta

The problem of estimating an unknown phase $ \varphi $ using two-level probes in the presence of unital phase-covariant noise and using finite resources is investigated. We introduce a simple model in which the phase-imprinting operation on…

Quantum Physics · Physics 2016-10-05 Rosanna Nichols , Thomas R. Bromley , Luis A. Correa , Gerardo Adesso

Cryo-electron microscopy (cryo-EM) has revolutionized structural biology by enabling near-atomic-level visualization of biomolecular assemblies. However, the exponential growth in cryo-EM data throughput and complexity, coupled with diverse…

Quantitative Methods · Quantitative Biology 2026-02-25 Weining Fu , Kai Shu , Kui Xu , Qiangfeng Cliff Zhang

Measuring the lifetime of fluorescent emitters by time-correlated single photon counting (TCSPC) is a routine procedure in many research areas spanning from nanophotonics to biology. The precision of such measurement depends on the number…

Instrumentation and Detectors · Physics 2019-07-18 Dorian Bouchet , Valentina Krachmalnicoff , Ignacio Izeddin

Differential privacy has become a cornerstone in the development of privacy-preserving learning algorithms. This work addresses optimizing differentially private kernel learning within the empirical risk minimization (ERM) framework. We…

Machine Learning · Statistics 2026-04-30 Bonwoo Lee , Cheolwoo Park , Jeongyoun Ahn