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Related papers: Preventing Covid59

200 papers

The COVID-19 pandemic has been a major challenge to humanity, with 12.7 million confirmed cases as of July 13th, 2020 [1]. In previous work, we described how Artificial Intelligence can be used to tackle the pandemic with applications at…

Computers and Society · Computer Science 2020-08-21 Alexandra Luccioni , Joseph Bullock , Katherine Hoffmann Pham , Cynthia Sin Nga Lam , Miguel Luengo-Oroz

Tremendous effort has been given to the development of diagnostic tests, preventive vaccines, and therapeutic medicines for coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Much of…

Genomics · Quantitative Biology 2020-04-30 Rui Wang , Yuta Hozumi , Changchuan Yin , Guo-Wei Wei

The world has seen in 2020 an unprecedented global outbreak of SARS-CoV-2, a new strain of coronavirus, causing the COVID-19 pandemic, and radically changing our lives and work conditions. Many scientists are working tirelessly to find a…

Information Retrieval · Computer Science 2020-05-18 Pierre Le Bras , Azimeh Gharavi , David A. Robb , Ana F. Vidal , Stefano Padilla , Mike J. Chantler

The accurate prediction of B-cell epitopes is critical for guiding vaccine development against infectious diseases, including SARS and COVID-19. This study explores the use of a deep neural network (DNN) model to predict B-cell epitopes for…

Machine Learning · Computer Science 2024-12-03 Xinyu Shi , Yixin Tao , Shih-Chi Lin

In the context of continued spread of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 and the emergence of new variants, the demand for rapid, accurate, and frequent detection is increasing. Besides, the new predominant strain,…

Antibodies are crucial proteins produced by the immune system to eliminate harmful foreign substances and have become pivotal therapeutic agents for treating human diseases. To accelerate the discovery of antibody therapeutics, there is…

Machine Learning · Computer Science 2024-10-17 Hirofumi Tsuruta , Hiroyuki Yamazaki , Ryota Maeda , Ryotaro Tamura , Akihiro Imura

Under the global health emergency caused by coronavirus disease 2019 (COVID-19), efficient and specific therapies are urgently needed. Compared with traditional small-molecular drugs, antibody therapies are relatively easy to develop and as…

Biomolecules · Quantitative Biology 2020-06-19 Jiahui Chen , Kaifu Gao , Rui Wang , Duc Duy Nguyen , Guo-Wei Wei

As the infection of 2019-nCoV coronavirus is quickly developing into a global pneumonia epidemic, careful analysis of its transmission and cellular mechanisms is sorely needed. In this report, we re-analyzed the computational approaches and…

Genomics · Quantitative Biology 2020-04-28 Chengxin Zhang , Wei Zheng , Xiaoqiang Huang , Eric W. Bell , Xiaogen Zhou , Yang Zhang

With the rapid spread of the novel coronavirus (COVID-19) across the globe and its continuous mutation, it is of pivotal importance to design a system to identify different known (and unknown) variants of SARS-CoV-2. Identifying particular…

Quantitative Methods · Quantitative Biology 2021-10-13 Sarwan Ali , Bikram Sahoo , Naimat Ullah , Alexander Zelikovskiy , Murray Patterson , Imdadullah Khan

Treating and preventing Human Immunodeficiency Virus (HIV) remains a critical global health challenge. While antiretroviral therapy provides a path toward viral suppression -- effectively eliminating an individual's transmission risk --…

Physics and Society · Physics 2026-05-21 Akseli Kangaslahti , Davin Choo , Milind Tambe , Alastair van Heerden , Cheryl Johnson

COVID-19 is a virus with high transmission rate that demands rapid identification of the infected patients to reduce the spread of the disease. The current gold-standard test, Reverse-Transcription Polymerase Chain Reaction (RT-PCR), has a…

Metagenomic datasets from pangolin tissue specimens have previously yielded SARS-related coronaviruses which show high homology in their receptor binding domain to SARS-CoV-2, suggesting a potential zoonotic source for this feature of the…

Genomics · Quantitative Biology 2022-03-02 Adrian Jones , Daoyu Zhang , Yuri Deigin , Steven C. Quay

The large-scale evolution of the SARS-CoV-2 virus has been marked by rapid turnover of genetic clades. New variants show intrinsic changes, notably increased transmissibility, as well as antigenic changes that reduce the cross-immunity…

Populations and Evolution · Quantitative Biology 2022-07-20 Matthijs Meijers , Denis Ruchnewitz , Marta Łuksza , Michael Lässig

The novelty of new human coronavirus COVID-19/SARS-CoV-2 and the lack of effective drugs and vaccines gave rise to a wide variety of strategies employed to fight this worldwide pandemic. Many of these strategies rely on the repositioning of…

Molecular Networks · Quantitative Biology 2021-06-09 Giulia Fiscon , Federica Conte , Lorenzo Farina , Paola Paci

CRISPR-Cas mediated immunity in bacteria allows bacterial populations to protect themselves against pathogens. However, it also exposes them to the dangers of auto-immunity by developing protection that targets its own genome. Using a…

Populations and Evolution · Quantitative Biology 2018-11-12 Serena Bradde , Thierry Mora , Aleksandra M. Walczak

Corona VIrus Disease abbreviated as COVID-19 is a novel virus which is initially identified in Wuhan of China in December of 2019 and now this deadly disease has spread all over the world. According to World Health Organization (WHO), a…

Machine Learning · Computer Science 2023-08-10 Mamata Das , P. J. A. Alphonse , Selvakumar K

We introduce a comprehensive screening platform for the COVID-19 (a.k.a., SARS-CoV-2) pneumonia. The proposed AI-based system works on chest x-ray (CXR) images to predict whether a patient is infected with the COVID-19 disease. Although the…

Rapid, sensitive detection of biomolecules is important for improved testing methods for viruses as well as biomarkers and environmental hormones. For example, testing for SARS-CoV-2 is essential in the fight against the COVID-19 pandemic.…

The SARS-CoV2 virus has caused a lot of tribulation to the human population. Predictive modeling that can accurately determine whether a person is infected with COVID-19 is imperative. The study proposes a novel approach that utilizes deep…

Image and Video Processing · Electrical Eng. & Systems 2021-11-23 Jash Dalvi , Aziz Bohra

The Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2), or Covid-19, burst into a pandemic in the beginning of 2020. An unprecedented worldwide effort involving academic institutions, regulatory agencies and industry is facing…

Dynamical Systems · Mathematics 2021-04-16 Cristiane M. Batistela , Diego P. F. Correa , Átila M Bueno , José R. C. Piqueira