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We propose two novel loss functions, Multiplicative Loss and Confidence-Adaptive Multiplicative Loss, for semantic segmentation in medical and cellular images. Although Cross Entropy and Dice Loss are widely used, their additive combination…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Yuto Yokoi , Kazuhiro Hotta

This study introduces a novel and accurate approach to breast cancer classification using histopathology images. It systematically compares leading Convolutional Neural Network (CNN) models across varying image datasets, identifies their…

Computer Vision and Pattern Recognition · Computer Science 2024-10-07 Gary Murphy , Raghubir Singh

Medical image data are usually imbalanced across different classes. One-class classification has attracted increasing attention to address the data imbalance problem by distinguishing the samples of the minority class from the majority…

Image and Video Processing · Electrical Eng. & Systems 2022-04-15 Long Gao , Chang Liu , Dooman Arefan , Ashok Panigrahy , Shandong Wu

Breast cancer is one of the leading causes of death across the world in women. Early diagnosis of this type of cancer is critical for treatment and patient care. Computer-aided detection (CAD) systems using convolutional neural networks…

Image and Video Processing · Electrical Eng. & Systems 2019-09-27 Sara Hosseinzadeh Kassani , Peyman Hosseinzadeh Kassani , Michal J. Wesolowski , Kevin A. Schneider , Ralph Deters

Histopathological image segmentation is a laborious and time-intensive task, often requiring analysis from experienced pathologists for accurate examinations. To reduce this burden, supervised machine-learning approaches have been adopted…

Computer Vision and Pattern Recognition · Computer Science 2024-09-12 Vishnuvardhan Purma , Suhas Srinath , Seshan Srirangarajan , Aanchal Kakkar , Prathosh A. P

Digitizing pathological images into gigapixel Whole Slide Images (WSIs) has opened new avenues for Computational Pathology (CPath). As positive tissue comprises only a small fraction of gigapixel WSIs, existing Multiple Instance Learning…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Wenhao Tang , Sheng Huang , Heng Fang , Fengtao Zhou , Bo Liu , Qingshan Liu

Intelligent analysis of medical imaging plays a crucial role in assisting clinical diagnosis. However, achieving efficient and high-accuracy image classification in resource-constrained computational environments remains challenging. This…

Computer Vision and Pattern Recognition · Computer Science 2025-08-18 Jingsong Xia , Yue Yin , Xiuhan Li

The existing barely-supervised medical image segmentation (BSS) methods, adopting a registration-segmentation paradigm, aim to learn from data with very few annotations to mitigate the extreme label scarcity problem. However, this paradigm…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Junming Su , Zhiqiang Shen , Peng Cao , Jinzhu Yang , Osmar R. Zaiane

Digital whole slide images (WSIs) are generally captured at microscopic resolution and encompass extensive spatial data. Directly feeding these images to deep learning models is computationally intractable due to memory constraints, while…

Image and Video Processing · Electrical Eng. & Systems 2024-11-22 Manahil Raza , Ruqayya Awan , Raja Muhammad Saad Bashir , Talha Qaiser , Nasir M. Rajpoot

Recently, deep learning models have achieved great success in computer vision applications, relying on large-scale class-balanced datasets. However, imbalanced class distributions still limit the wide applicability of these models due to…

Computer Vision and Pattern Recognition · Computer Science 2021-08-05 Yechan Kim , Younkwan Lee , Moongu Jeon

Masked Autoencoders (MAEs) have emerged as a dominant strategy for self-supervised representation learning in natural images, where models are pre-trained to reconstruct masked patches with a pixel-wise mean squared error (MSE) between…

Image and Video Processing · Electrical Eng. & Systems 2025-07-16 Chetan Madan , Aarjav Satia , Soumen Basu , Pankaj Gupta , Usha Dutta , Chetan Arora

Visual-semantic embedding models have been recently proposed and shown to be effective for image classification and zero-shot learning, by mapping images into a continuous semantic label space. Although several approaches have been proposed…

Computer Vision and Pattern Recognition · Computer Science 2015-12-23 Zhou Ren , Hailin Jin , Zhe Lin , Chen Fang , Alan Yuille

Classifying fine-grained lesions is challenging due to minor and subtle differences in medical images. This is because learning features of fine-grained lesions with highly minor differences is very difficult in training deep neural…

Computer Vision and Pattern Recognition · Computer Science 2023-08-14 Wongi Park , Jongbin Ryu

Self-supervised learning (SSL) methods targeting scene images have seen a rapid growth recently, and they mostly rely on either a dedicated dense matching mechanism or a costly unsupervised object discovery module. This paper shows that…

Computer Vision and Pattern Recognition · Computer Science 2023-10-02 Ke Zhu , Minghao Fu , Jianxin Wu

Using only global image-class labels, weakly-supervised learning methods, such as class activation mapping, allow training CNNs to jointly classify an image, and locate regions of interest associated with the predicted class. However,…

Image and Video Processing · Electrical Eng. & Systems 2022-05-06 Soufiane Belharbi , Marco Pedersoli , Ismail Ben Ayed , Luke McCaffrey , Eric Granger

Breast cancer presents a significant healthcare challenge globally, demanding precise diagnostics and effective treatment strategies, where histopathological examination of Hematoxylin and Eosin (H&E) stained tissue sections plays a central…

Image and Video Processing · Electrical Eng. & Systems 2024-08-06 Linhao Qu , Chengsheng Zhang , Guihui Li , Haiyong Zheng , Chen Peng , Wei He

Hispathological image segmentation algorithms play a critical role in computer aided diagnosis technology. The development of weakly supervised segmentation algorithm alleviates the problem of medical image annotation that it is…

Computer Vision and Pattern Recognition · Computer Science 2022-05-19 Ziniu Qian , Kailu Li , Maode Lai , Eric I-Chao Chang , Bingzheng Wei , Yubo Fan , Yan Xu

Recent advances in whole-slide image (WSI) scanners and computational capabilities have significantly propelled the application of artificial intelligence in histopathology slide analysis. While these strides are promising, current…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Weiyi Wu , Chongyang Gao , Joseph DiPalma , Soroush Vosoughi , Saeed Hassanpour

Histopathology image classification is crucial for the accurate identification and diagnosis of various diseases but requires large and diverse datasets. Obtaining such datasets, however, is often costly and time-consuming due to the need…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Leire Benito-Del-Valle , Aitor Alvarez-Gila , Itziar Eguskiza , Cristina L. Saratxaga

Deep neural networks are increasingly applied in automated histopathology. Yet, whole-slide images (WSIs) are often acquired at gigapixel sizes, rendering them computationally infeasible to analyze entirely at high resolution. Diagnostic…

Image and Video Processing · Electrical Eng. & Systems 2026-02-10 Tarun G , Naman Malpani , Gugan Thoppe , Sridharan Devarajan