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The rich longitudinal individual level data available from electronic health records (EHRs) can be used to examine treatment effect heterogeneity. However, estimating treatment effects using EHR data poses several challenges, including…

Patient similarity assessment, which identifies patients similar to a given patient, can help improve medical care. The assessment can be performed using Electronic Medical Records (EMRs). Patient similarity measurement requires converting…

Information Retrieval · Computer Science 2022-09-20 Hoda Memarzadeh , Nasser Ghadiri , Matthias Samwald , Maryam Lotfi Shahreza

This paper uses rule search techniques for the early identification of emergency homeless shelter clients who are at risk of becoming long term or chronic shelter users. Using a data set from a major North American shelter containing 12…

Computers and Society · Computer Science 2023-04-27 Caleb John , Geoffrey G. Messier

There is strong interest among payers to identify emerging healthcare cost drivers to support early intervention. However, many challenges arise in analyzing large, high dimensional, and noisy healthcare data. In this paper, we propose a…

Applications · Statistics 2019-07-22 Ta-Hsin Li , Huijing Jiang , Kevin Tran , Gigi Yuen-Reed , Bob Kelley , Thomas Halvorson

Due to the popularity of smartphones and wearable devices nowadays, mobile health (mHealth) technologies are promising to bring positive and wide impacts on people's health. State-of-the-art decision-making methods for mHealth rely on some…

Machine Learning · Computer Science 2017-08-15 Feiyun Zhu , Jun Guo , Zheng Xu , Peng Liao , Junzhou Huang

It is not clear how to target patients who are most likely to benefit from digital care management programs ex-ante, a shortcoming of current risk score based approaches. This study focuses on defining impactability by identifying those…

Quantitative Methods · Quantitative Biology 2019-05-16 Heather Mattie , Patrick Reidy , Patrik Bachtiger , Emily Lindemer , Mohammad Jouni , Trishan Panch

The healthcare sector has experienced a rapid accumulation of digital data recently, especially in the form of electronic health records (EHRs). EHRs constitute a precious resource that IS researchers could utilize for clinical applications…

Machine Learning · Computer Science 2024-11-06 Thiti Suttaket , L Vivek Harsha Vardhan , Stanley Kok

The estimation of heterogeneous treatment effects (HTEs) has attracted considerable interest in many disciplines, most prominently in medicine and economics. Contemporary research has so far primarily focused on continuous and binary…

Methodology · Statistics 2022-10-07 Susanne Dandl , Andreas Bender , Torsten Hothorn

Low attendance levels in medical appointments have been associated with poor health outcomes and efficiency problems for service providers. To address this problem, healthcare managers could aim at improving attendance levels or minimizing…

Machine Learning · Computer Science 2020-12-11 David Barrera Ferro , Sally Brailsford , Cristián Bravo , Honora Smith

Individual-level effectiveness and healthcare resource use (HRU) data are routinely collected in trial-based economic evaluations. While effectiveness is often expressed in terms of utility scores derived from some health-related quality of…

Methodology · Statistics 2024-07-31 Andrea Gabrio

Exhaustive subgroup treatment effect plots are constructed by displaying all subgroup treatment effects of interest against subgroup sample size, providing a useful overview of the observed treatment effect heterogeneity in a clinical…

Methodology · Statistics 2026-02-09 Björn Bornkamp , Jiarui Lu , Frank Bretz

Patient-level health economic data collected alongside clinical trials are an important component of the process of technology appraisal, with a view to informing resource allocation decisions. For end of life treatments, such as cancer…

Applications · Statistics 2020-11-24 Andrea Gabrio

Analyzing data from multiple sources offers valuable opportunities to improve the estimation efficiency of causal estimands. However, this analysis also poses many challenges due to population heterogeneity and data privacy constraints.…

Methodology · Statistics 2025-10-23 Rong Zhao , Jason Falvey , Xu Shi , Vernon M. Chinchilli , Chixiang Chen

Systemic lupus erythematosus (SLE) is a complex heterogeneous disease with many manifestational facets. We propose a data-driven approach to discover probabilistic independent sources from multimodal imperfect EHR data. These sources…

In this paper, we propose a new approach to causal inference with panel data. Instead of using panel data to adjust for differences in the distribution of unobserved heterogeneity between the treated and comparison groups, we instead use…

Econometrics · Economics 2025-12-01 Brantly Callaway , Derek Dyal , Pedro H. C. Sant'Anna , Emmanuel S. Tsyawo

Predicting health risks from electronic health records (EHR) is a topic of recent interest. Deep learning models have achieved success by modeling temporal and feature interaction. However, these methods learn insufficient representations…

Machine Learning · Computer Science 2023-12-19 Zhihao Yu , Chaohe Zhang , Yasha Wang , Wen Tang , Jiangtao Wang , Liantao Ma

Population aging is a global challenge, leading to increased demand for health care and social services for the elderly. Home Health Care (HHC) is a vital solution to serve this segment of the population. Given the increasing demand for…

In causal inference, estimating heterogeneous treatment effects (HTE) is critical for identifying how different subgroups respond to interventions, with broad applications in fields such as precision medicine and personalized advertising.…

Machine Learning · Computer Science 2024-07-02 Jiehui Zhou , Linxiao Yang , Xingyu Liu , Xinyue Gu , Liang Sun , Wei Chen

We consider the problem of allocating multiple heterogeneous resources geographically and over time to meet demands that require some subset of the available resource types simultaneously at a specified time, location, and duration. The…

Optimization and Control · Mathematics 2022-06-15 Arden Baxter , Pinar Keskinocak , Mohit Singh

Heart rate prediction is vital for personalized health monitoring and fitness, while it frequently faces a critical challenge in real-world deployment: data heterogeneity. We classify it in two key dimensions: source heterogeneity from…

Machine Learning · Computer Science 2026-02-25 Zhengdong Huang , Zicheng Xie , Wentao Tian , Jingyu Liu , Lunhong Dong , Peng Yang