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We study a simple model of DNA evolution in a growing population of cells. Each cell contains a nucleotide sequence which randomly mutates at cell division. Cells divide according to a branching process. Following typical parameter values…

Probability · Mathematics 2020-06-05 David Cheek , Tibor Antal

Consider a population that is expanding in two-dimensional space. Suppose we collect data from a sample of individuals taken at random either from the entire population, or from near the outer boundary of the population. A quantity of…

Probability · Mathematics 2026-03-16 Shirshendu Ganguly , Jason Schweinsberg , Yubo Shuai

We consider the genealogical tree of a stationary continuous state branching process with immigration. For a sub-critical stable branching mechanism, we consider the genealogical tree of the extant population at some fixed time and prove…

Probability · Mathematics 2020-05-21 Romain Abraham , Jean-François Delmas , Hui He

We ask the question "when will natural selection on a gene in a spatially structured population cause a detectable trace in the patterns of genetic variation observed in the contemporary population?". We focus on the situation in which…

Probability · Mathematics 2016-11-17 Alison Etheridge , Nic Freeman , Sarah Penington , Daniel Straulino

We consider a stochastic individual-based population model with competition, trait-structure affecting reproduction and survival, and changing environment. The changes of traits are described by jump processes, and the dynamics can be…

Probability · Mathematics 2022-01-17 Benoît Henry , Sylvie Méléard , Viet Chi Tran

We are interested in the impact of natural selection in a prey-predator community. We introduce an individual-based model of the community that takes into account both prey and predator phenotypes. Our aim is to understand the phenotypic…

Populations and Evolution · Quantitative Biology 2015-02-19 Manon Costa , Céline Hauzy , Nicolas Loeuille , Sylvie Méléard

We review and extend results for mutation, selection, genetic drift, and migration in a one-dimensional continuous population. The population is described by a continuous limit of the stepping stone model, which leads to the stochastic…

Populations and Evolution · Quantitative Biology 2011-04-14 K. S. Korolev , Mikkel Avlund , Oskar Hallatschek , David R. Nelson

In this paper we study a class of stochastic individual-based models that describe the evolution of haploid populations where each individual is characterised by a phenotype and a genotype. The phenotype of an individual determines its…

Probability · Mathematics 2017-08-07 Martina Baar , Anton Bovier

We are interested in modelling Darwinian evolution, resulting from the interplay of phenotypic variation and natural selection through ecological interactions. Our models are rooted in the microscopic, stochastic description of a population…

Probability · Mathematics 2016-08-16 Nicolas Champagnat , Régis Ferrière , Sylvie Méléard

The goal of this paper is to provide mathematically rigorous tools for modelling the evolution of a community of interacting individuals. We model the population by a measure space where the measure determines the abundance of individual…

Probability · Mathematics 2017-05-17 Thomas Cass , Terry Lyons

In building practical applications of evolutionary computation (EC), two optimizations are essential. First, the parameters of the search method need to be tuned to the domain in order to balance exploration and exploitation effectively.…

Neural and Evolutionary Computing · Computer Science 2023-04-25 Hormoz Shahrzad , Risto Miikkulainen

Multitype branching processes are ideal for studying the population dynamics of stem cell populations undergoing mutation accumulation over the years following transplant. In such stochastic models, several quantities are of clinical…

Populations and Evolution · Quantitative Biology 2021-11-17 Timothy C Stutz , Janet S. Sinsheimer , Mary Sehl , Jason Xu

We study a universal object for the genealogy of a sample in populations with mutations: the critical birth-death process with Poissonian mutations, conditioned on its population size at a fixed time horizon. We show how this process arises…

Probability · Mathematics 2014-07-30 G. Achaz , C. Delaporte , A. Lambert

Evolution is a dynamic process. The two classical forces of evolution are mutation and selection. Assuming small mutation rates, evolution can be predicted based solely on the fitness differences between phenotypes. Predicting an…

Populations and Evolution · Quantitative Biology 2015-03-23 Benedikt Bauer , Chaitanya S. Gokhale

Existing theoretical models of evolution focus on the relative fitness advantages of different mutants in a population while the dynamic behavior of the population size is mostly left unconsidered. We here present a generic stochastic model…

Populations and Evolution · Quantitative Biology 2010-10-20 Anna Melbinger , Jonas Cremer , Erwin Frey

We study in detail a recently proposed simple discrete model for evolution on smooth landscapes. An asymptotic solution of this model for long times is constructed. We find that the dynamics of the population are governed by correlation…

Condensed Matter · Physics 2009-10-28 David A. Kessler , Herbert Levine , Douglas Ridgway , Lev Tsimring

In this paper we consider two continuous-mass population models as analogues of logistic branching random walks, one is supported on a finite trait space and the other one is supported on an infinite trait space. For the first model with…

Probability · Mathematics 2013-04-18 Anton Bovier , Shi-Dong Wang

We investigate a continuous time, probability measure-valued dynamical system that describes the process of mutation-selection balance in a context where the population is infinite, there may be infinitely many loci, and there are weak…

Populations and Evolution · Quantitative Biology 2011-09-20 Steven N. Evans , David Steinsaltz , Kenneth W. Wachter

We consider a stationary continuous model of random size population with non-neutral mutations using a continuous state branching process with non-homogeneous immigration. We assume the type (or mutation) of the immigrants is random given…

Probability · Mathematics 2013-07-26 Hongwei Bi , Jean-François Delmas

Density dependent Markov population processes in large populations of size $N$ were shown by Kurtz (1970, 1971) to be well approximated over finite time intervals by the solution of the differential equations that describe their average…

Probability · Mathematics 2014-10-15 A. D. Barbour , Kais Hamza , Haya Kaspi , Fima Klebaner