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Metabolic heterogeneity is widely recognised as the next challenge in our understanding of non-genetic variation. A growing body of evidence suggests that metabolic heterogeneity may result from the inherent stochasticity of intracellular…

Molecular Networks · Quantitative Biology 2020-10-08 Mona K Tonn , Philipp Thomas , Mauricio Barahona , Diego A Oyarzún

We consider the problem of efficiently learning mixtures of a large number of spherical Gaussians, when the components of the mixture are well separated. In the most basic form of this problem, we are given samples from a uniform mixture of…

Data Structures and Algorithms · Computer Science 2017-11-01 Oded Regev , Aravindan Vijayaraghavan

We propose an efficient way to sample from a class of structured multivariate Gaussian distributions which routinely arise as conditional posteriors of model parameters that are assigned a conditionally Gaussian prior. The proposed…

Computation · Statistics 2016-06-28 Anirban Bhattacharya , Antik Chakraborty , Bani K. Mallick

Creating low dimensional representations of a high dimensional data set is an important component in many machine learning applications. How to cluster data using their low dimensional embedded space is still a challenging problem in…

Machine Learning · Computer Science 2023-03-27 Zahra Moslehi , Abdolreza Mirzaei , Mehran Safayani

We consider the problem of inferring the unknown parameters of a stochastic biochemical network model from a single measured time-course of the concentration of some of the involved species. Such measurements are available, e.g., from…

Molecular Networks · Quantitative Biology 2011-11-22 Christian L. Muller , Rajesh Ramaswamy , Ivo F. Sbalzarini

We describe and analyze a broad class of mixture models for real-valued multivariate data in which the probability density of observations within each component of the model is represented as an arbitrary combination of basis functions.…

Methodology · Statistics 2025-02-28 M. E. J. Newman

Generalised linear models for multi-class classification problems are one of the fundamental building blocks of modern machine learning tasks. In this manuscript, we characterise the learning of a mixture of $K$ Gaussians with generic means…

The Expectation-Maximization (EM) algorithm is a fundamental tool in unsupervised machine learning. It is often used as an efficient way to solve Maximum Likelihood (ML) estimation problems, especially for models with latent variables. It…

Quantum Physics · Physics 2020-07-08 Iordanis Kerenidis , Alessandro Luongo , Anupam Prakash

A mixture of factor analyzers is a semi-parametric density estimator that generalizes the well-known mixtures of Gaussians model by allowing each Gaussian in the mixture to be represented in a different lower-dimensional manifold. This…

Machine Learning · Statistics 2015-10-23 Heysem Kaya , Albert Ali Salah

This paper presents a new model called infinite mixtures of multivariate Gaussian processes, which can be used to learn vector-valued functions and applied to multitask learning. As an extension of the single multivariate Gaussian process,…

Machine Learning · Computer Science 2013-07-29 Shiliang Sun

We present a method using Feynman-like diagrams to calculate the statistical properties of random many-body potentials. This method provides a promising alternative to existing techniques typically applied to this class of problems, such as…

Other Condensed Matter · Physics 2015-06-23 Rupert Small , Sebastian Müller

Motivated by previous work on moment varieties for Gaussian distributions and their mixtures, we study moment varieties for two other statistically important two-parameter distributions: the inverse Gaussian and gamma distributions. In…

Algebraic Geometry · Mathematics 2024-12-04 Oskar Henriksson , Lisa Seccia , Teresa Yu

Recursive estimation of nonlinear dynamical systems is an important problem that arises in several engineering applications. Consistent and accurate propagation of uncertainties is important to ensuring good estimation performance. It is…

Systems and Control · Computer Science 2016-03-16 Dilshad Raihan Akkam Veettil , Suman Chakravorty

We consider the problem of Gaussian mixture clustering in the high-dimensional limit where the data consists of $m$ points in $n$ dimensions, $n,m \rightarrow \infty$ and $\alpha = m/n$ stays finite. Using exact but non-rigorous methods…

Machine Learning · Statistics 2017-03-24 Thibault Lesieur , Caterina De Bacco , Jess Banks , Florent Krzakala , Cris Moore , Lenka Zdeborová

This paper studies identifiability and convergence behaviors for parameters of multiple types in finite mixtures, and the effects of model fitting with extra mixing components. First, we present a general theory for strong identifiability,…

Statistics Theory · Mathematics 2015-01-13 Nhat Ho , XuanLong Nguyen

Given a finite admixture model whose components and weights are unknown, let the number of identifiable components be a function of the amount of data sampled from a known distribution on the unit simplex. We use techniques from stochastic…

Statistics Theory · Mathematics 2025-09-03 Michele Caprio , Sayan Mukherjee

This paper establishes the theoretical foundations for the asymptotic separability of Gaussian Mixture Models (GMMs) in high dimensions by extending the classical Feldman-H\'ajek theorem. We first prove that a countable mixture of Gaussian…

Statistics Theory · Mathematics 2026-01-13 Umberto Michelucci

This work is concerned with kinetic equations with velocity of constant magnitude. We propose a quadrature method of moments based on the Poisson kernel, called Poisson-EQMOM. The derived moment closure systems are well defined for all…

Computational Physics · Physics 2024-11-20 Yihong Chen , Qian Huang , Wen-An Yong , Ruixi Zhang

Estimating parameters of mixture model has wide applications ranging from classification problems to estimating of complex distributions. Most of the current literature on estimating the parameters of the mixture densities are based on…

Machine Learning · Statistics 2020-06-23 Yuantong Li , Qi Ma , Sujit K. Ghosh

Financial studies require volatility based models which provides useful insights on risks related to investments. Stochastic volatility models are one of the most popular approaches to model volatility in such studies. The asset returns…

Methodology · Statistics 2021-10-26 Soham Mukherjee